| الأسهم المعلقة | 97,986,634 shares |
| أسهم المطلعين | ٢٬١٣٥٬٩٠٣ shares |
| ملكية المطلعين | ٢٫١٨ % |
| إجمالي المطلعين | 41 |
درجات مزاج المطلعين
تكشف نقاط مزاج المطلعين عن الشركات التي تم شراؤها من قبل المطلعين على الشركات.
إنه نتيجة لنموذج كمي متطور ومتعدد العوامل يحدد الشركات التي تتمتع بأعلى مستويات التراكم الداخلي. يستخدم نموذج التسجيل مزيجًا من صافي عدد المطلعين الذين اشتروا 90 يومًا السابقة، وإجمالي الأسهم المشتراة كنسبة مئوية من التعويم، وإجمالي الأسهم المملوكة من قبل المطلعين. ويتراوح الرقم من 0 إلى 100، وتشير الأرقام الأعلى إلى مستوى أعلى من التراكم لأقرانه، و50 هو المتوسط.
تكرار التحديث: يومياً
راجع أفضل اختيارات المطلعين، والتي توفر قائمة بالشركات التي تتمتع بأعلى تراكم من المطلعين.
درجة مزاج المسؤولين
تكشف درجة مزاج المسؤولين عن الشركات التي يتم شراؤها من قبل مسؤولي الشركات.
بحكم التعريف، فإن مسؤولي الشركة هم من المطلعين على الشركة، ولكن على عكس بعض المطلعين الآخرين (10% من المساهمين وأعضاء مجلس الإدارة)، يعمل المسؤولون في الشركة على أساس يومي، ويستخدمون أموالهم الخاصة عند التداول. (10% من المساهمين وأعضاء مجلس الإدارة غالبًا ما يكونون مديري صناديق يديرون أموال الآخرين.) وعلى هذا النحو، تكون الصفقات الداخلية التي يقوم بها المسؤولون أكثر أهمية ويجب التعامل معها بشكل مناسب.
مثل درجة مزاج المطلعين، فإن درجة مزاج الموظف هي نتيجة لنموذج كمي متطور ومتعدد العوامل يحدد الشركات التي تتمتع بأعلى مستويات تراكم الموظفين.
تكرار التحديث: يومياً
راجع أفضل خيارات المطلعين، والتي توفر قائمة بالشركات التي تتمتع بأعلى المزاجات الداخلية.
المقاييس الرئيسية من الداخل
توضح هذه البطاقة كيفية تصنيف الشركة وفقًا لمختلف المقاييس الداخلية. يوضح الترتيب المئوي كيفية مقارنة هذه الشركة بالشركات الأخرى في الأسواق الأمريكية. تشير التصنيفات الأعلى إلى أوضاع أفضل.
على سبيل المثال، من المقبول عمومًا أن الشراء من الداخل يعد مؤشرًا إيجابيًا، وبالتالي فإن الشركات التي لديها المزيد من الشراء من الداخل ستحتل مرتبة أعلى من الشركات التي لديها قدر أقل من الشراء من الداخل (أو حتى البيع من الداخل).
نسبة الأسهم العائمة المشتراة من قبل المطلعين (المرتبة)
0.000 %( )
622 out of 11244النسبة المئوية للأسهم العائمة المشتراة من قبل المطلعين هي إجمالي عدد الأسهم المشتراة من قبل المطلعين مطروحًا منه إجمالي عدد الأسهم المباعة من قبل المطلعين في آخر 90 يومًا، مقسومًا على إجمالي الأسهم العائمة ومضروبًا في 100.
الرسم البياني للتداول من الداخل
aTyr Pharma, Inc. يتم عرض الصفقات الداخلية في الرسم البياني التالي. المطلعون هم مسؤولين أو مدراء أو مستثمرين مهمون في الشركة. بشكل عام، من غير القانوني بشكل عام أن يقوم المطلعون بإجراء عمليات تداول في شركاتهم بناءً على معلومات مادية وغير عامة. وهذا لا يعني أنه من غير القانوني بالنسبة لهم إجراء أي صفقات تجارية في شركاتهم الخاصة. ومع ذلك، يجب عليهم الإبلاغ عن جميع الصفقات إلى هيئة الأوراق المالية والبورصات عبر النموذج 4.
قائمة المطلعين ومقاييس الربحية
يعرض هذا الجدول قائمة المطلعين المعروفين، ويتم إنشاؤه تلقائيًا من التصريحات التي تم الكشف عنها إلى هيئة الأوراق المالية والبورصات. بالإضافة إلى الأسماء، وأحدث منصب، والمدير، أو المسؤول، أو تعيين المالك بنسبة 10%، فإننا نقدم أحدث الممتلكات التي تم الكشف عنها. بالإضافة إلى ذلك، عندما يكون ذلك ممكنًا، فإننا نقدم الأداء التجاري التاريخي للمطلعين على بواطن الأمور. الأداء التجاري التاريخي هو المتوسط المرجح لأداء معاملات الشراء الفعلية في السوق المفتوحة التي أجراها المطلعون من الداخل. لمزيد من المعلومات حول كيفية حساب ذلك، شاهد هذا البرنامج التعليمي عبر الإنترنت على يوتيوب.
See our leaderboard of most profitable insider traders.
| مطلع | متوسط الربح (%) | الأسهم مملوكة |
التقسيم المعدل |
|---|---|---|---|
|
Srinivas Akkaraju
10% Owner -
|
١٬٨٦٦٬١٢٦ | ١٣٣٬٢٩٥ | |
|
Alta Partners VIII, L.P.
10% Owner -
|
١٬٧٧٨٬٠٦٤ | ١٢٧٬٠٠٥ | |
| Ashraf Amanullah See Remarks - [O] | ٢٦٬٢٦٤ | ١٬٨٧٦ | |
| Ashlock Melissa A. See Remarks - [O] | ١٣٦٬٣٢٨ | ٩٬٧٣٨ | |
|
James C Blair
Director, 10% Owner -
[D]
|
٢٠٬٠٠٠ | ١٢٩٬١٣٠ | |
| Kelly Blackburn See Remarks - [O] | ٥٥٨ | ٤٠ | |
| Stan Blackburn - | ٢٣٬٩٠٨ | ١٬٧٠٨ | |
| John T Blake Senior Vice President, Finance - [O] | ١٬٩٣٢ | ١٣٨ | |
| Jill Marie Broadfoot Chief Financial Officer - [O] | ٣١٬٧٦٣ | ٣١٬٧٦٣ | |
|
Chp Ii Lp
10% Owner -
|
١٬٧٥٨٬١٥٨ | ١٢٥٬٥٨٣ | |
| John K Clarke Director - [D] | ١٩٬٧٩٧ | ١٩٬٧٩٧ | |
| Frederic Chereau COO & President - [O] | ٢٥٬٧٣٤ | ١٬٨٣٨ | |
| Chrzanowski Holly D. See Remarks - [O] | ٣٬٧٧٠ | ٢٦٩ |
| مطلع | متوسط الربح (%) | الأسهم مملوكة |
التقسيم المعدل |
|---|---|---|---|
| Timothy P Coughlin Director - [D] | ٥٦٬٠٠٠ | ٥٦٬٠٠٠ | |
| Andrew Cubitt | ٢٥٬٠٠٠ | ||
|
Associates Domain
10% Owner -
|
١٨٬٨٥٨ | ١٬٣٤٧ | |
|
DP VIII Associates, L.P.
10% Owner -
|
١٣٬٤١٤ | ٩٥٨ | |
|
Domain Partners VIII, L.P.
10% Owner -
|
١٬٨٠٧٬٨٢٠ | ١٢٩٬١٣٠ | |
|
EcoR1 Capital Fund Qualified, L.P.
10% Owner -
|
٠ | ٠ | |
| Kathryn E Falberg Director - [D] | ٢٥٬١٤٤ | ١٬٧٩٦ | |
|
James E Flynn
10% Owner -
|
٢٥٥٬٧٦٤ | ١٨٬٢٦٩ | |
| Mark Alan Goldberg | ٢٠٬٠٠٠ | ||
| Marcy Graham | ١٢٬٠٢٣ | ||
| Jane A Gross Director - [D] | ٩٬٧٥٠ | ٩٬٧٥٠ | |
| Hatfield Jeffrey S. | ١٬٤٢٨ | ||
|
Kamdar Kim P.
10% Owner -
|
١٨٬٨٥٨ | ١٬٣٤٧ | |
| David John King | ١٥٠٬٠٠٠ |
| مطلع | متوسط الربح (%) | الأسهم مملوكة |
التقسيم المعدل |
|---|---|---|---|
| Nancy Krueger General Counsel - [O] | ٢٦٬٥٥٥ | ٢٦٬٥٥٥ | |
| Svetlana Lucas Director - [D] | ٦٬٠٠٠ | ٦٬٠٠٠ | |
| John Mendlein Director - [D] | ٦١٥٬٣٨٢ | ٤٣٬٩٥٦ | |
| Grove Matsuoka See Remarks - [O] | ١٢٬٤١٢ | ٨٨٧ | |
| McKew John C. | ٤٠٬٠٠٠ | ||
| Amir Nashat Director - [D] | ١٧٬٦٣٨ | ١٬٢٦٠ | |
|
Polaris Venture Management Co. V, L.L.C.
10% Owner -
|
١٧٬٦٣٨ | ١٬٢٦٠ | |
| Fred Ramsdell | ٥٬٣٩٣ | ||
| Ravindran Sanuj K. | ٤٠٬٠٠٠ | ||
| Paul Schimmel Director - [D] | ١٬١٠١٬٠٥٦ | ١٬١٠١٬٠٥٦ | |
| Sanjay Shukla President and CEO, Director - [D] [O] | ١٤٦٬٩٢٣ | ١٤٦٬٩٢٣ | |
|
Sofinnova Venture Partners IX, L.P.
10% Owner -
|
١٬٨٦٦٬١٢٦ | ١٣٣٬٢٩٥ | |
| Weiner David M. Chief Medical Officer - [O] | ١٠٬٠٥٦ | ٧١٨ | |
| Sara Zaknoen Director - [D] | ٦٬٠٠٠ | ٦٬٠٠٠ |
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تتبع سجلات المشتريات الداخلية - تحليل الأرباح على المدى القصير
في هذا القسم، نقوم بتحليل ربحية كل عملية شراء داخلية غير مخطط لها في السوق المفتوحة تم إجراؤها في ATYR / aTyr Pharma, Inc.. يساعد هذا التحليل على فهم ما إذا كان المطلعون على بواطن الأمور يحققون عوائد غير طبيعية باستمرار، ويستحق المتابعة. هذا التحليل لمدة سنة واحدة بعد كل تجارة، و النتائج نظرية .
يوضح الجدول التالي أحدث عمليات الشراء في السوق المفتوحة والتي لم تكن جزءًا من خطة التداول التلقائية.
السعر المعدل هو السعر المعدل حسب التقسيم. المشاركات المعدلة هي المشاركات المعدلة حسب التقسيم.
تتبع سجلات المبيعات الداخلية - تحليل الخسائر على المدى القصير
في هذا القسم، نقوم بتحليل تجنب الخسارة على المدى القصير لكل عملية بيع داخلية غير مخطط لها في السوق المفتوحة تم إجراؤها في ATYR / aTyr Pharma, Inc.. قد يشير النمط الثابت لتجنب الخسارة إلى أن معاملات البيع المستقبلية قد تتنبأ بانخفاض الأسعار. هذا التحليل لمدة سنة واحدة بعد كل تجارة، و النتائج نظرية .
يوضح الجدول التالي أحدث مبيعات السوق المفتوحة التي لم تكن جزءًا من خطة التداول التلقائية.
السعر المعدل هو السعر المعدل حسب التقسيم. المشاركات المعدلة هي المشاركات المعدلة حسب التقسيم.
تاريخ المعاملات
انقر على أيقونة الرابط للاطلاع على سجل المعاملات الكامل. ستظهر علامة X في العمود 10b-5 للمعاملات المُبلّغ عنها ضمن خطة التداول الآلي 10b5-1.
| تاريخ الملف |
تاريخ التبادل |
النموذج | المطلع | المؤشر | التغيير في القيمة | الرمز | مباشر | سعر التمرين |
سعر الوحدة |
الوحدة المتغيرة |
القيمة المتغيرة (1 ألف) |
الخيارات المتبقية |
الأسهم المتبقية |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-03-17 | 2025-03-17 | 4 | Gross Jane A | ATYR | Common Stock | D | ٤٫٠٠٠٠ | ٣٬٧٥٠ | ١٥ | ٩٬٧٥٠ | ||||
| 2025-02-04 | 2025-02-03 | 4 | Shukla Sanjay | ATYR | Common Stock | D | ١٠٬٣٧٥ | ١٤٦٬٩٢٣ | ||||||
| 2025-02-04 | 2025-02-04 | 4 | Broadfoot Jill Marie | ATYR | Common Stock | D | ٣٫٧٨٠٠ | ١٬٢٥٤ | ٥ | ٣١٬٧٦٣ | ||||
| 2025-02-04 | 2025-02-03 | 4 | Broadfoot Jill Marie | ATYR | Common Stock | D | ٣٬٧٥٠ | ٣٣٬٠١٧ | ||||||
| 2025-02-04 | 2025-02-04 | 4 | Krueger Nancy | ATYR | Common Stock | D | ٣٫٧٨٠٠ | ٨٩٩ | ٣ | ٢٦٬٥٥٥ | ||||
| 2025-02-04 | 2025-02-03 | 4 | Krueger Nancy | ATYR | Common Stock | D | ٢٬٦٨٧ | ٢٧٬٤٥٤ | ||||||
| 2024-07-24 | 2024-07-24 | 4 | SCHIMMEL PAUL | ATYR | Common Stock | I | ١٫٩٣١٩ | ٥٢٬٣٠٠ | ١٠١ | ٤١٣٬٠٢٣ | ||||
| 2024-07-24 | 2024-07-23 | 4 | SCHIMMEL PAUL | ATYR | Common Stock | I | ١٫٨١٦٣ | ٦٬٦٤٨ | ١٢ | ٣٦٠٬٧٢٣ | ||||
| 2024-07-24 | 2024-07-22 | 4 | SCHIMMEL PAUL | ATYR | Common Stock | I | ١٫٧٤١٧ | ٤١٬٠٥٢ | ٧٢ | ٣٥٤٬٠٧٥ | ||||
| 2024-06-06 | 2024-06-05 | 4 | Krueger Nancy | ATYR | Common Stock | D | ١٫٨٥٥٢ | ٥٬٠٠٠ | ٩ | ٢٢٬٢٦٧ | ||||
| 2024-06-03 | 2024-05-30 | 4 | Coughlin Timothy P | LIFE | Common Stock | I | ١٫٧٥٠٠ | ٥٠٬٠٠٠ | ٨٨ | ٥٦٬٠٠٠ | ||||
| 2024-06-03 | 2024-05-31 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | ١٫٧٩٠٠ | ٥٬٠٠٠ | ٩ | ٢٧٬٩٦٠ | ||||
| 2024-06-03 | 2024-05-31 | 4 | Shukla Sanjay | LIFE | Common Stock | D | ١٫٨٠٧٠ | ٢٠٬٠٠٠ | ٣٦ | ١٣٦٬٥٤٨ | ||||
| 2024-02-06 | 2024-02-05 | 4 | Shukla Sanjay | LIFE | Common stock | D | ١٠٬٣٧٥ | ١١٦٬٥٤٨ | ||||||
| 2024-02-06 | 2024-02-06 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | ١٫٦٩٠٠ | ١٬٥٩٠ | ٣ | ٢٠٬٨٢١ | ||||
| 2024-02-06 | 2024-02-05 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | ٣٬٧٥٠ | ٢٢٬٤١١ | ||||||
| 2024-02-06 | 2024-02-05 | 4 | Krueger Nancy | LIFE | Common stock | D | ٢٬٦٨٨ | ١٤٬٧٦٧ | ||||||
| 2023-12-12 | 2023-12-12 | 4 | Shukla Sanjay | LIFE | Common Stock | D | ١٫١٧٨٠ | ١٢٬٠٠٠ | ١٤ | ١٠٦٬١٧٣ | ||||
| 2023-12-12 | 2023-12-11 | 4 | Shukla Sanjay | LIFE | Common Stock | D | ١٫١٧٠٠ | ٣٬٠٠٠ | ٤ | ٩٤٬١٧٣ | ||||
| 2023-11-13 | 2023-11-13 | 4 | Shukla Sanjay | LIFE | Common Stock | D | ١٫١١١٠ | ١٣٬٥٧٨ | ١٥ | ٩١٬١٧٣ | ||||
| 2023-11-13 | 2023-11-10 | 4 | Shukla Sanjay | LIFE | Common Stock | D | ١٫١٣٨٠ | ١٬٤٢٢ | ٢ | ٧٧٬٥٩٥ | ||||
| 2023-08-01 | 2023-07-28 | 4 | Shukla Sanjay | LIFE | Common Stock | D | ٢٫٠١٤٩ | ١٥٬٠٠٠ | ٣٠ | ٧٦٬١٧٣ | ||||
| 2023-05-19 | 2023-05-17 | 4 | Coughlin Timothy P | LIFE | Common Stock | I | ٦٬٠٠٠ | ٦٬٠٠٠ | ||||||
| 2023-05-19 | 2023-05-17 | 4 | Coughlin Timothy P | LIFE | Common Stock | D | ٦٬٠٠٠ | ٠ | ||||||
| 2023-05-11 | 2023-05-10 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٢٫٢٥٠٠ | ٢٠٠٬٠٠٠ | ٤٥٠ | ٣١٣٬٠٢٣ | ||||
| 2023-04-28 | 2023-04-26 | 4 | CLARKE JOHN K | LIFE | Common Stock | D | ٦٬٠٠٠ | ١٩٬٧٩٧ | ||||||
| 2023-04-28 | 2023-04-26 | 4 | Coughlin Timothy P | LIFE | Common stock | D | ٦٬٠٠٠ | ٦٬٠٠٠ | ||||||
| 2023-04-28 | 2023-04-26 | 4 | Lucas Svetlana | LIFE | Common stock | D | ٦٬٠٠٠ | ٦٬٠٠٠ | ||||||
| 2023-04-28 | 2023-04-26 | 4 | SCHIMMEL PAUL | LIFE | Common stock | D | ٦٬٠٠٠ | ٨٬٨٩٠ | ||||||
| 2023-04-28 | 2023-04-26 | 4 | Zaknoen Sara | LIFE | Common stock | D | ٦٬٠٠٠ | ٦٬٠٠٠ | ||||||
| 2023-04-28 | 2023-04-26 | 4 | Gross Jane A | LIFE | Common stock | D | ٦٬٠٠٠ | ٦٬٠٠٠ | ||||||
| 2023-02-06 | 2023-02-03 | 4 | Krueger Nancy | LIFE | Common stock | D | ٢٬٦٨٨ | ٧٬٠٧٩ | ||||||
| 2023-02-06 | 2023-02-06 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | ٢٫٣٦٠٠ | ١٬٥٦٦ | ٤ | ١٥٬٤٦٠ | ||||
| 2023-02-06 | 2023-02-03 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | ٣٬٧٥٠ | ١٧٬٠٢٦ | ||||||
| 2023-02-06 | 2023-02-03 | 4 | Shukla Sanjay | LIFE | Common stock | D | ١٠٬٣٧٥ | ٦١٬١٧٣ | ||||||
| 2022-11-21 | 2022-11-21 | 4 | Shukla Sanjay | LIFE | Common Stock | D | ٢٫١٤٠٥ | ١٠٬٠٠٠ | ٢١ | ٥٠٬٧٩٨ | ||||
| 2022-07-06 | 2022-07-01 | 4 | Shukla Sanjay | LIFE | Common Stock | D | ٢٫٨٧٧٦ | ١٥٬٠٠٠ | ٤٣ | ٤٠٬٧٩٨ | ||||
| 2022-05-26 | 2022-05-24 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | ٢٫٨١ | ٨٨٬٠٩٧ | ٨٨٬٠٩٧ | |||||
| 2022-05-26 | 2022-05-24 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | ٢٫٨١ | ٧٥٬٣٤٧ | ٧٥٬٣٤٧ | |||||
| 2022-05-26 | 2022-05-24 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٢٫٨١ | ٥١٦٬٢٨٠ | ٥١٦٬٢٨٠ | |||||
| 2022-04-28 | 2022-04-26 | 4 | CLARKE JOHN K | LIFE | Restricted Stock Units | D | ٦٬٠٠٠ | ٦٬٠٠٠ | ||||||
| 2022-04-28 | 2022-04-26 | 4 | SCHIMMEL PAUL | LIFE | Restricted Stock Units | D | ٦٬٠٠٠ | ٦٬٠٠٠ | ||||||
| 2022-04-28 | 2022-04-26 | 4 | Coughlin Timothy P | LIFE | Restricted Stock Units | D | ٦٬٠٠٠ | ٦٬٠٠٠ | ||||||
| 2022-04-28 | 2022-04-26 | 4 | Zaknoen Sara | LIFE | Restricted Stock Units | D | ٦٬٠٠٠ | ٦٬٠٠٠ | ||||||
| 2022-04-28 | 2022-04-26 | 4 | Gross Jane A | LIFE | Restricted Stock Units | D | ٦٬٠٠٠ | ٦٬٠٠٠ | ||||||
| 2022-04-28 | 2022-04-26 | 4 | Lucas Svetlana | LIFE | Restricted Stock Units | D | ٦٬٠٠٠ | ٦٬٠٠٠ | ||||||
| 2022-02-07 | 2022-02-03 | 4 | Broadfoot Jill Marie | LIFE | Restricted Stock Units | D | ١٥٬٠٠٠ | ١٥٬٠٠٠ | ||||||
| 2022-02-07 | 2022-02-03 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | ٥٫٥٢ | ٣٠٬٠٠٠ | ٣٠٬٠٠٠ | |||||
| 2022-02-07 | 2022-02-03 | 4 | Krueger Nancy | LIFE | Restricted Stock Units | D | ١٠٬٧٥٠ | ١٠٬٧٥٠ | ||||||
| 2022-02-07 | 2022-02-03 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | ٥٫٥٢ | ٢١٬٥٠٠ | ٢١٬٥٠٠ | |||||
| 2022-02-07 | 2022-02-03 | 4 | Shukla Sanjay | LIFE | Restricted Stock Units | D | ٤١٬٥٠٠ | ٤١٬٥٠٠ | ||||||
| 2022-02-07 | 2022-02-03 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٥٫٥٢ | ٨٣٬٠٠٠ | ٨٣٬٠٠٠ | |||||
| 2022-01-18 | 2022-01-13 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | ٦٫٧٥٠٠ | ١٬٩٢٣ | ١٣ | ١٢٬١١٢ | ||||
| 2022-01-10 | 2022-01-07 | 4 | Shukla Sanjay | LIFE | Common Stock | D | ٦٫٧٦١٣ | ٥٬٠٠٠ | ٣٤ | ٢٥٬٧٩٨ | ||||
| 2021-11-15 | 2021-11-15 | 4 | Shukla Sanjay | LIFE | Common Stock | D | ٨٫٥٧٥٠ | ٢٬٥٠٠ | ٢١ | ٢٠٬٧٩٨ | ||||
| 2021-09-22 | 2021-09-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٢٥٠٬٠٠٠ | ٦٧٩٬١٤٣ | ||||||
| 2021-09-22 | 2021-09-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | ٢٥٠٬٠٠٠ | ٢٬٨٩٠ | ||||||
| 2021-09-22 | 2021-09-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | ٨٫٠٠٠٠ | ٢٥٠٬٠٠٠ | ٢٬٠٠٠ | ٢٥٢٬٨٩٠ | ||||
| 2021-05-25 | 2021-05-21 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | ٤٫٣٤٠٠ | ٢٬٥٠٠ | ١١ | ١٠٨٬٠٨٣ | ||||
| 2021-05-25 | 2021-05-21 | 4 | Krueger Nancy | LIFE | Employee Stock Option (Right to buy) | D | ٤٫٤٥ | ٥٩٬٠٠٠ | ٥٩٬٠٠٠ | |||||
| 2021-05-25 | 2021-05-21 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (Right to buy) | D | ٤٫٤٥ | ٢٠٧٬٠٠٠ | ٢٠٧٬٠٠٠ | |||||
| 2021-05-25 | 2021-05-21 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (Right to buy) | D | ٤٫٤٥ | ٥٤٬٠٠٠ | ٥٤٬٠٠٠ | |||||
| 2021-05-25 | 2021-05-21 | 4 | Zaknoen Sara | LIFE | Stock Option (right to buy) | D | ٤٫٤٥ | ٢٬٢٨٥ | ٢٬٢٨٥ | |||||
| 2021-05-20 | 2021-05-18 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٣٫٩٨٠٠ | ٥٠٬٠٠٠ | ١٩٩ | ١١٣٬٠٢٣ | ||||
| 2021-05-20 | 2021-05-18 | 4 | Shukla Sanjay | LIFE | Common Stock | D | ٤٫٠١٠٠ | ١٠٬٠٠٠ | ٤٠ | ١٨٬٢٩٨ | ||||
| 2021-04-29 | 2021-04-28 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | ٤٫٢١ | ١٬٤٢٨ | ١٬٤٢٨ | |||||
| 2021-04-29 | 2021-04-28 | 4 | Lucas Svetlana | LIFE | Stock Option (right to buy) | D | ٤٫٢١ | ١٬٤٢٨ | ١٬٤٢٨ | |||||
| 2021-04-29 | 2021-04-28 | 4 | Gross Jane A | LIFE | Stock Option (right to buy) | D | ٤٫٢١ | ١٬٤٢٨ | ١٬٤٢٨ | |||||
| 2021-04-29 | 2021-04-28 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | ٤٫٢١ | ١٬٤٢٨ | ١٬٤٢٨ | |||||
| 2021-04-29 | 2021-04-28 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | ٤٫٢١ | ١٬٤٢٨ | ١٬٤٢٨ | |||||
| 2021-03-09 | 2021-02-04 | 4/A | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٤٫٥٢ | ١١٢٬٤٦٩ | ١١٢٬٤٦٩ | |||||
| 2021-03-09 | 2020-05-26 | 4/A | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٤٫٠٦ | ٧٣٬١٤٢ | ٧٣٬١٤٢ | |||||
| 2021-02-09 | 2021-02-09 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | ٧٫٦٦٠٠ | ٣٩٠ | ٣ | ٩٬٨٣٣ | ||||
| 2021-02-09 | 2021-02-06 | 4 | Broadfoot Jill Marie | LIFE | Restricted Stock Unit | D | ٨٩٢ | ٠ | ||||||
| 2021-02-09 | 2021-02-06 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | ٨٩٢ | ١٠٬٢٢٣ | ||||||
| 2021-02-09 | 2021-02-09 | 4 | Shukla Sanjay | LIFE | Common stock | D | ٧٫٦٦٠٠ | ٧٧٨ | ٦ | ٨٬٢٩٨ | ||||
| 2021-02-09 | 2021-02-06 | 4 | Shukla Sanjay | LIFE | Restricted Stock Unit | D | ١٬٧٨٥ | ٠ | ||||||
| 2021-02-09 | 2021-02-06 | 4 | Shukla Sanjay | LIFE | Common stock | D | ١٬٧٨٥ | ٩٬٠٧٦ | ||||||
| 2021-02-08 | 2021-02-04 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٤٫٥٢ | ١٢٠٬٠٠٠ | ١٢٠٬٠٠٠ | |||||
| 2021-02-08 | 2021-02-04 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | ٤٫٥٢ | ٤٥٬٠٠٠ | ٤٥٬٠٠٠ | |||||
| 2021-02-08 | 2021-02-04 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | ٤٫٥٢ | ٥٠٬٠٠٠ | ٥٠٬٠٠٠ | |||||
| 2020-09-03 | 2020-09-02 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | ٤٫٠١٠٠ | ٧٬٢٦٠ | ٢٩ | ١١٠٬٥٨٣ | ||||
| 2020-09-03 | 2020-08-28 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | ٤٫٠٠٠٠ | ١٠٠ | ٠ | ١١٧٬٨٤٣ | ||||
| 2020-08-28 | 2020-08-27 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | ٤٫٠٩٠٠ | ٥٬٤٤٠ | ٢٢ | ١١٧٬٩٤٣ | ||||
| 2020-08-28 | 2020-08-26 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | ٤٫٢٩٦٠ | ٢٬٢٠٠ | ٩ | ١٢٣٬٣٨٣ | ||||
| 2020-06-23 | 2020-06-19 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | ٤٫٢٢٠٠ | ١٬٨٥٠ | ٨ | ٩٬١٥٣ | ||||
| 2020-06-23 | 2020-06-19 | 4 | Shukla Sanjay | LIFE | Common Stock | D | ٤٫٢٧٠٠ | ٦٬٠٠٠ | ٢٦ | ٧٬٢٩١ | ||||
| 2020-05-28 | 2020-05-26 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٤٫٠٦ | ٨٠٬٠٠٠ | ٠ | |||||
| 2020-05-28 | 2020-05-26 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | ٤٫٠٦ | ٣٠٬٠٠٠ | ٣٠٬٠٠٠ | |||||
| 2020-05-28 | 2020-05-26 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | ٤٫٠٦ | ٣٠٬٠٠٠ | ٣٠٬٠٠٠ | |||||
| 2020-05-28 | 2020-05-20 | 4 | Krueger Nancy | LIFE | Common Stock | D | ٣٫٦٢٠٠ | ٣٢٢ | ١ | ٢٬٧٣٥ | ||||
| 2020-05-28 | 2020-05-16 | 4 | Krueger Nancy | LIFE | Restricted Stock Unit | D | ٨٩٢ | ٠ | ||||||
| 2020-05-28 | 2020-05-16 | 4 | Krueger Nancy | LIFE | Common Stock | D | ٨٩٢ | ٣٬٠٥٧ | ||||||
| 2020-05-22 | 2020-05-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٣٫٦٣٩٠ | ٨٬٤٤٧ | ٣١ | ٤٢٩٬١٤٣ | ||||
| 2020-05-08 | 2020-05-06 | 4 | Lucas Svetlana | LIFE | Stock Option (right to buy) | D | ٣٫٦٥ | ١٬٤٢٨ | ١٬٤٢٨ | |||||
| 2020-05-08 | 2020-05-06 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | ٣٫٦٥ | ١٬٤٢٨ | ١٬٤٢٨ | |||||
| 2020-05-08 | 2020-05-06 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | ٣٫٦٥ | ١٬٤٢٨ | ١٬٤٢٨ | |||||
| 2020-05-08 | 2020-05-06 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | ٣٫٦٥ | ١٬٤٢٨ | ١٬٤٢٨ | |||||
| 2020-05-08 | 2020-05-06 | 4 | Gross Jane A | LIFE | Stock Option (right to buy) | D | ٣٫٦٥ | ١٬٤٢٨ | ١٬٤٢٨ | |||||
| 2020-05-08 | 2020-05-06 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | ٣٫٦٥ | ١٬٤٢٨ | ١٬٤٢٨ | |||||
| 2020-02-11 | 2020-02-10 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٤٫٢٥٠٠ | ٢٥٤٬٠٠٠ | ١٬٠٨٠ | ٤٣٧٬٥٩٠ | ||||
| 2020-02-07 | 2020-02-07 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | ٤٫٠٣٠٠ | ٣٧٥ | ٢ | ٧٬١٢٥ | ||||
| 2020-02-07 | 2020-02-06 | 4 | Broadfoot Jill Marie | LIFE | Restricted Stock Unit | D | ٨٩٣ | ٨٩٣ | ||||||
| 2020-02-07 | 2020-02-06 | 4 | Broadfoot Jill Marie | LIFE | Common stock | D | ٨٩٣ | ٧٬٥٠٠ | ||||||
| 2020-02-07 | 2020-02-05 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | ٤٫٣٩ | ٢٣٬٣٥٩ | ٢٣٬٣٥٩ | |||||
| 2020-02-07 | 2020-02-05 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | ٤٫٣٩ | ١٣٬٧٧٨ | ١٣٬٧٧٨ | |||||
| 2020-02-07 | 2020-02-07 | 4 | Shukla Sanjay | LIFE | Common stock | D | ٤٫٠٣٠٠ | ٧٤٥ | ٣ | ١٬٢٩١ | ||||
| 2020-02-07 | 2020-02-06 | 4 | Shukla Sanjay | LIFE | Restricted Stock Unit | D | ١٬٧٨٦ | ١٬٧٨٦ | ||||||
| 2020-02-07 | 2020-02-06 | 4 | Shukla Sanjay | LIFE | Common stock | D | ١٬٧٨٦ | ٢٬٠٣٦ | ||||||
| 2020-02-07 | 2020-02-05 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٤٫٣٩ | ٣٩٬٣٢٧ | ٣٩٬٣٢٧ | |||||
| 2019-07-02 | 2019-06-28 | 4 | Gross Jane A | LIFE | Stock Option (right to buy) | D | ٥٫١٣ | ٢٬٢٨٥ | ٢٬٢٨٥ | |||||
| 2019-07-02 | 2019-06-28 | 4 | Lucas Svetlana | LIFE | Stock Option (right to buy) | D | ٥٫١٣ | ٢٬٢٨٥ | ٢٬٢٨٥ | |||||
| 2019-05-20 | 2019-05-17 | 4 | Krueger Nancy | LIFE | Common Stock | D | ٠٫٤٥٠١ | ٤٬٦٥١ | ٢ | ٢٥٬٣٤٨ | ||||
| 2019-05-20 | 2019-05-16 | 4 | Krueger Nancy | LIFE | Restricted Stock Units | D | ٠٫٠٠ | ١٢٬٥٠٠ | ١٢٬٥٠٠ | |||||
| 2019-05-20 | 2019-05-16 | 4 | Krueger Nancy | LIFE | Common Stock | D | ١٢٬٥٠٠ | ٢٩٬٩٩٩ | ||||||
| 2019-05-10 | 2019-05-08 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | ٠٫٥٨ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2019-05-10 | 2019-05-08 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | ٠٫٥٨ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2019-05-10 | 2019-05-08 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | ٠٫٥٨ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2019-05-10 | 2019-05-08 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | ٠٫٥٨ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2019-05-10 | 2019-05-08 | 4 | MENDLEIN JOHN | LIFE | Stock Option (right to buy) | D | ٠٫٥٨ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2019-05-10 | 2019-05-08 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | ٠٫٥٨ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2019-04-16 | 2019-04-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٠٫٥٤١٠ | ١٬٨٤٨٬٤٢٨ | ١٬٠٠٠ | ٢٬٥٧٠٬٢٤٢ | ||||
| 2019-02-08 | 3 | Krueger Nancy | LIFE | Common Stock | D | ٢٩٬٩٩٨ | ||||||||
| 2019-02-08 | 3 | Krueger Nancy | LIFE | Common Stock | D | ٢٩٬٩٩٨ | ||||||||
| 2019-02-08 | 3 | Krueger Nancy | LIFE | Common Stock | D | ٢٩٬٩٩٨ | ||||||||
| 2019-02-08 | 2019-02-06 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | ٠٫٥٢ | ١٢٥٬٠٠٠ | ١٢٥٬٠٠٠ | |||||
| 2019-02-08 | 2019-02-06 | 4 | Broadfoot Jill Marie | LIFE | Restricted Stock Unit | D | ٢٥٬٠٠٠ | ٢٥٬٠٠٠ | ||||||
| 2019-02-08 | 2019-02-06 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | ٠٫٥٢ | ٥٠٬٠٠٠ | ٥٠٬٠٠٠ | |||||
| 2019-02-08 | 2019-02-06 | 4 | Shukla Sanjay | LIFE | Restricted Stock Unit | D | ٥٠٬٠٠٠ | ٥٠٬٠٠٠ | ||||||
| 2019-02-08 | 2019-02-06 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٠٫٥٢ | ٢٠٠٬٠٠٠ | ٢٠٠٬٠٠٠ | |||||
| 2018-12-26 | 2018-12-21 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | ٠٫٤٢٣٦ | ١٩٥٬٠٠٠ | ٨٣ | ٦١٥٬٣٨٢ | ||||
| 2018-12-26 | 2018-12-20 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | ٠٫٤١٢٩ | ٥٠٬٠٠٠ | ٢١ | ٤٢٠٬٣٨٢ | ||||
| 2018-11-28 | 2018-11-26 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٠٫٥٤٢٠ | ١٤٧٬٢٢٥ | ٨٠ | ٨٨٢٬٣٠٢ | ||||
| 2018-09-21 | 2018-09-20 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | ٠٫٨٣٥٢ | ٣٨٬٠٠٠ | ٣٢ | ٩٠٬٠٠٠ | ||||
| 2018-09-21 | 2018-09-19 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | ٠٫٨١٢٢ | ٢٦٬٠٠٠ | ٢١ | ٥٢٬٠٠٠ | ||||
| 2018-09-18 | 2018-09-14 | 4 | Broadfoot Jill Marie | LIFE | Common Stock | D | ٠٫٧٣٢٩ | ٢٦٬٠٠٠ | ١٩ | ٢٦٬٠٠٠ | ||||
| 2018-09-05 | 2018-09-04 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٠٫٧٥٧١ | ٢٠٬٧٤٩ | ١٦ | ٧٣٥٬٠٧٧ | ||||
| 2018-09-05 | 2018-08-31 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٠٫٧١٦٠ | ٢٢٬٠٠٠ | ١٦ | ٧١٤٬٣٢٨ | ||||
| 2018-08-31 | 2018-08-30 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٠٫٧٥٥٩ | ٨٩٬٢٧٥ | ٦٧ | ٦٩٢٬٣٢٨ | ||||
| 2018-08-31 | 2018-08-29 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٠٫٧١٩٩ | ٧٥٬١٣٦ | ٥٤ | ٦٠٣٬٠٥٣ | ||||
| 2018-08-01 | 2018-07-30 | 4 | Broadfoot Jill Marie | LIFE | Employee Stock Option (right to buy) | D | ٠٫٨٢ | ٢٠٠٬٠٠٠ | ٢٠٠٬٠٠٠ | |||||
| 2018-06-07 | 2018-05-31 | 4 | Amanullah Ashraf | LIFE | Restricted Stock Units | D | ٠٫٠٠ | ٣٬٣٣٣ | ٣٬٣٣٣ | |||||
| 2018-06-07 | 2018-05-31 | 4 | Amanullah Ashraf | LIFE | Common Stock | D | ٣٬٣٣٣ | ٢٦٬٢٦٤ | ||||||
| 2018-05-21 | 2018-05-18 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٠٫٩٩٦٣ | ١٥٠٬٠٠٠ | ١٤٩ | ٥٢٧٬٩١٧ | ||||
| 2018-05-17 | 2018-05-15 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | ١٫٣٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2018-05-17 | 2018-05-15 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | ١٫٣٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2018-05-17 | 2018-05-15 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | ١٫٣٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2018-05-17 | 2018-05-15 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | ١٫٣٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2018-05-17 | 2018-05-15 | 4 | MENDLEIN JOHN | LIFE | Stock Option (right to buy) | D | ١٫٣٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2018-05-17 | 2018-05-15 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | ١٫٣٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2018-05-17 | 2018-05-15 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | ١٫٣٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2018-05-16 | 2018-05-16 | 4 | EcoR1 Capital Fund Qualified, L.P. | LIFE | Common Stock | D | ٠٫٨١١١ | ٢٬٧٣٣٬٢٣١ | ٢٬٢١٧ | ٠ | ||||
| 2018-05-16 | 2018-05-15 | 4 | EcoR1 Capital Fund Qualified, L.P. | LIFE | Common Stock | D | ١٫٤٢٦٨ | ١٢١٬٢٩٤ | ١٧٣ | ٢٬٧٣٣٬٢٣١ | ||||
| 2018-05-16 | 2018-05-14 | 4 | EcoR1 Capital Fund Qualified, L.P. | LIFE | Common Stock | D | ١٫٧١٦٧ | ٣٥٤٬٧٩١ | ٦٠٩ | ٢٬٨٥٤٬٥٢٥ | ||||
| 2018-05-02 | 3 | Blackburn Stan By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 2001 | LIFE | Common Stock | I | ٢٣٬٩٠٨ | ||||||||
| 2018-05-02 | 3 | Blackburn Stan By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 2001 | LIFE | Common Stock | I | ٢٣٬٩٠٨ | ||||||||
| 2018-05-02 | 3 | Blackburn Stan By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 2001 | LIFE | Common Stock | I | ٢٣٬٩٠٨ | ||||||||
| 2018-02-08 | 2018-02-06 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٣٫٣٠ | ٣٠٠٬٠٠٠ | ٣٠٠٬٠٠٠ | |||||
| 2018-02-08 | 2018-02-08 | 4 | Amanullah Ashraf | LIFE | Common Stock | D | ٣٫٤٠٠٠ | ١٬٤٠٢ | ٥ | ١٬٩٣٢ | ||||
| 2018-02-08 | 2018-02-07 | 4 | Amanullah Ashraf | LIFE | Restricted Stock Units | D | ٠٫٠٠ | ٣٬٣٣٤ | ٦٬٦٦٦ | |||||
| 2018-02-08 | 2018-02-07 | 4 | Amanullah Ashraf | LIFE | Common Stock | D | ٣٬٣٣٤ | ٣٬٣٣٤ | ||||||
| 2018-02-08 | 2018-02-06 | 4 | Amanullah Ashraf | LIFE | Employee Stock Option (right to buy) | D | ٣٫٣٠ | ١٠٠٬٠٠٠ | ١٠٠٬٠٠٠ | |||||
| 2018-02-08 | 2018-02-08 | 4 | Blake John T | LIFE | Common Stock | D | ٣٫٤٠٠٠ | ١٬٤٠٢ | ٥ | ١٬٩٣٢ | ||||
| 2018-02-08 | 2018-02-07 | 4 | Blake John T | LIFE | Restricted Stock Units | D | ٠٫٠٠ | ٣٬٣٣٤ | ٦٬٦٦٦ | |||||
| 2018-02-08 | 2018-02-07 | 4 | Blake John T | LIFE | Common Stock | D | ٣٬٣٣٤ | ٣٬٣٣٤ | ||||||
| 2018-02-08 | 2018-02-06 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | ٣٫٣٠ | ٧٥٬٠٠٠ | ٧٥٬٠٠٠ | |||||
| 2018-02-08 | 2018-02-06 | 4 | King David John | LIFE | Employee Stock Option (right to buy) | D | ٣٫٣٠ | ١٥٠٬٠٠٠ | ١٥٠٬٠٠٠ | |||||
| 2018-01-02 | 2018-01-02 | 4 | MENDLEIN JOHN | LIFE | Stock Option (right to buy) | D | ٣٫٨٠ | ٣٢٬٠٠٠ | ٣٢٬٠٠٠ | |||||
| 2017-12-14 | 2017-11-13 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | ٣٫٩٥٠٠ | ١٬٠٨٣ | ٤ | ٣٬٢٠٩٬٣١٦ | ||||
| 2017-12-14 | 2017-11-10 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | ٤٫٠٠٠٨ | ٥٬٨٦٠ | ٢٣ | ٣٬٢١٠٬٣٩٩ | ||||
| 2017-12-14 | 2017-11-09 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | ٤٫١٥٠٤ | ٥٬٨١٩ | ٢٤ | ٣٬٢١٦٬٢٥٩ | ||||
| 2017-12-14 | 2017-11-08 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | ٤٫٣٠٠٠ | ١٬٠٧٠ | ٥ | ٣٬٢٢٢٬٠٧٨ | ||||
| 2017-12-14 | 2017-11-01 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | ٤٫٨٠٠٠ | ٢٤٬٧٢٨ | ١١٩ | ٣٬٢٢٣٬١٤٨ | ||||
| 2017-12-14 | 2017-10-01 | 4 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | ٥٫٠٥٠٠ | ٤٬٨٧٩ | ٢٥ | ٣٬١٩٨٬٤٢٠ | ||||
| 2017-11-03 | 2017-11-01 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٤٫٠٠ | ٤٥٠٬٠٠٠ | ٤٥٠٬٠٠٠ | |||||
| 2017-09-07 | 3 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | ٦٬٣٨٧٬٠٨٢ | ||||||||
| 2017-09-07 | 3 | EcoR1 Capital Fund Qualified, L.P. | ATYR | Common Stock | D | ٦٬٣٨٧٬٠٨٢ | ||||||||
| 2017-09-05 | 2017-08-31 | 4 | SCHIMMEL PAUL | LIFE | Warrant to Purchase Common Stock | I | ٤٫٦٤ | ٣٥٬٣٧٦ | ٣٥٬٣٧٦ | |||||
| 2017-09-05 | 2017-08-31 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٢٫٦٥٠٠ | ٩٤٬٣٣٦ | ٢٥٠ | ٣٧٧٬٩١٧ | ||||
| 2017-09-05 | 2017-08-31 | 4 | MENDLEIN JOHN | LIFE | Warrant to Purchase Common Stock | D | ٤٫٦٤ | ١٤٬١٥١ | ١٤٬١٥١ | |||||
| 2017-09-05 | 2017-08-31 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | ٢٫٦٥٠٠ | ٣٧٬٧٣٦ | ١٠٠ | ٣٦٧٬٨٨٣ | ||||
| 2017-05-11 | 3/A | Blackburn Stan By the J. Stanhope and Karlene S. Blackburn Family Trust U.T.D. May 9, 2001 | LIFE | Common Stock | I | ١١٬٨٠٥ | ||||||||
| 2017-05-11 | 2017-05-09 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | ٣٫١٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2017-05-11 | 2017-05-09 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | ٣٫١٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2017-05-11 | 2017-05-09 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | ٣٫١٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2017-05-11 | 2017-05-09 | 4 | Goldberg Mark Alan | LIFE | Stock Option (right to buy) | D | ٣٫١٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2017-05-11 | 2017-05-09 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | ٣٫١٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2017-05-11 | 2017-05-09 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | ٣٫١٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2017-05-11 | 2017-05-09 | 4 | AKKARAJU SRINIVAS | LIFE | Stock Option (right to buy) | D | ٣٫١٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2017-05-11 | 2017-05-09 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | ٣٫١٥ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2017-04-26 | 2017-04-24 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | ٣٫٠٠٠٠ | ١٢٤ | ٠ | ٣٢٧٬٦٤٧ | ||||
| 2017-04-20 | 2017-04-20 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | ٣٫٠٠٠٠ | ١٬٥٥٢ | ٥ | ٣٢٧٬٥٢٣ | ||||
| 2017-04-20 | 2017-04-18 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | ٣٫٠٠٠٠ | ١٬٠٠٠ | ٣ | ٣٢٥٬٩٧١ | ||||
| 2017-04-10 | 2017-04-07 | 4 | Coughlin Timothy P | LIFE | Stock Option (right to buy) | D | ٣٫٢٥ | ٣٢٬٠٠٠ | ٣٢٬٠٠٠ | |||||
| 2017-04-04 | 2017-04-03 | 4 | Hatfield Jeffrey S. | LIFE | Stock Option (right to buy) | D | ٣٫٥٠ | ٣٢٬٠٠٠ | ٣٢٬٠٠٠ | |||||
| 2017-02-09 | 2017-02-07 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٣٫٣٠ | ٦٥٬٠٠٠ | ٦٥٬٠٠٠ | |||||
| 2017-02-09 | 2017-02-07 | 4 | Ravindran Sanuj K. | LIFE | Employee Stock Option (right to buy) | D | ٣٫٣٠ | ٤٠٬٠٠٠ | ٤٠٬٠٠٠ | |||||
| 2017-02-09 | 2017-02-07 | 4 | Matsuoka Grove | LIFE | Employee Stock Option (right to buy) | D | ٣٫٣٠ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2017-02-09 | 2017-02-07 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | ٣٫٣٠ | ١٨٥٬٠٠٠ | ١٨٥٬٠٠٠ | |||||
| 2017-02-09 | 2017-02-07 | 4 | Blake John T | LIFE | Restricted Stock Unit | D | ١٠٬٠٠٠ | ١٠٬٠٠٠ | ||||||
| 2017-02-09 | 2017-02-07 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | ٣٫٣٠ | ٥٥٬٠٠٠ | ٥٥٬٠٠٠ | |||||
| 2017-02-09 | 2017-02-07 | 4 | King David John | LIFE | Employee Stock Option (right to buy) | D | ٣٫٣٠ | ٦٥٬٠٠٠ | ٦٥٬٠٠٠ | |||||
| 2017-02-09 | 2017-02-07 | 4 | Amanullah Ashraf | LIFE | Restricted Stock Unit | D | ١٠٬٠٠٠ | ١٠٬٠٠٠ | ||||||
| 2017-02-09 | 2017-02-07 | 4 | Amanullah Ashraf | LIFE | Employee Stock Option (right to buy) | D | ٣٫٣٠ | ٣٥٬٠٠٠ | ٣٥٬٠٠٠ | |||||
| 2016-12-22 | 2016-12-21 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٢٫٢٨١٨ | ١٠٬٠٠٠ | ٢٣ | ٧٢١٬٨١٤ | ||||
| 2016-12-22 | 2016-12-20 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٢٫٢٧٤٠ | ١٥٬٠٠٠ | ٣٤ | ٧١١٬٨١٤ | ||||
| 2016-12-21 | 2016-12-19 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | ٢٫١٩٨٠ | ٦٩٬٠٠٠ | ١٥٢ | ٣٢٤٬٩٧١ | ||||
| 2016-12-21 | 2016-12-20 | 4 | Amanullah Ashraf | LIFE | Common Stock | D | ٢٫٢٤٩٩ | ١١٬٠٠٠ | ٢٥ | ١١٬٠٠٠ | ||||
| 2016-12-19 | 2016-12-16 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٢٫٣٩٧٣ | ١٠٬٠٠٠ | ٢٤ | ٦٩٦٬٨١٤ | ||||
| 2016-12-19 | 2016-12-15 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٢٫٤٩٧٨ | ٤٠٬٠٠٠ | ١٠٠ | ٦٨٦٬٨١٤ | ||||
| 2016-12-19 | 2016-09-23 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ١٢٬٥٧٢ | ٦٤٦٬٨١٤ | ||||||
| 2016-12-19 | 2016-09-23 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | ١٢٬٥٧٢ | ٤٠٬٤٤٠ | ||||||
| 2016-09-22 | 2016-09-21 | 4 | King David John | LIFE | Employee Stock Option (right to buy) | D | ٣٫٢٩ | ١٤٥٬٠٠٠ | ١٤٥٬٠٠٠ | |||||
| 2016-09-15 | 2016-09-13 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | ٣٫٠٦ | ٢٥٬٠٠٠ | ٢٥٬٠٠٠ | |||||
| 2016-09-15 | 2016-09-13 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | ٣٫٠٦ | ١٩٬٠٠٠ | ١٩٬٠٠٠ | |||||
| 2016-09-15 | 2016-09-13 | 4 | Ravindran Sanuj K. | LIFE | Employee Stock Option (right to buy) | D | ٣٫٠٦ | ٤٥٬٥٠٠ | ٤٥٬٥٠٠ | |||||
| 2016-09-15 | 2016-09-13 | 4 | Amanullah Ashraf | LIFE | Employee Stock Option (right to buy) | D | ٣٫٠٦ | ٢٨٬٠٠٠ | ٢٨٬٠٠٠ | |||||
| 2016-09-15 | 2016-09-13 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٣٫٠٦ | ٢٧٬٥٠٠ | ٢٧٬٥٠٠ | |||||
| 2016-09-15 | 2016-09-13 | 4 | Matsuoka Grove | LIFE | Employee Stock Option (right to buy) | D | ٣٫٠٦ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2016-05-26 | 2016-05-24 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | ٣٫٣٣ | ١٨٬٠٠٠ | ١٨٬٠٠٠ | |||||
| 2016-05-26 | 2016-05-24 | 4 | AKKARAJU SRINIVAS | LIFE | Stock Option (right to buy) | D | ٣٫٣٣ | ١٨٬٠٠٠ | ١٨٬٠٠٠ | |||||
| 2016-05-26 | 2016-05-24 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | ٣٫٣٣ | ١٨٬٠٠٠ | ١٨٬٠٠٠ | |||||
| 2016-05-26 | 2016-05-24 | 4 | FALBERG KATHRYN E | LIFE | Stock Option (right to buy) | D | ٣٫٣٣ | ١٨٬٠٠٠ | ١٨٬٠٠٠ | |||||
| 2016-05-26 | 2016-05-24 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | ٣٫٣٣ | ١٨٬٠٠٠ | ١٨٬٠٠٠ | |||||
| 2016-05-26 | 2016-05-24 | 4 | Goldberg Mark Alan | LIFE | Stock Option (right to buy) | D | ٣٫٣٣ | ١٨٬٠٠٠ | ١٨٬٠٠٠ | |||||
| 2016-05-26 | 2016-05-24 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | ٣٫٣٣ | ١٨٬٠٠٠ | ١٨٬٠٠٠ | |||||
| 2016-05-11 | 2016-05-11 | 4 | Matsuoka Grove | LIFE | Common Stock | D | ٣٫٠٣٠٠ | ١٠٬٠٠٠ | ٣٠ | ١٢٬٤١٢ | ||||
| 2016-05-11 | 2016-05-09 | 4 | Matsuoka Grove | LIFE | Common Stock | D | ٣٫٠٨٠٠ | ٢٬٤١٢ | ٧ | ٢٬٤١٢ | ||||
| 2016-05-03 | 2016-05-03 | 4 | Matsuoka Grove | LIFE | Stock Option (right to buy) | D | ٣٫٦٧ | ١٤٥٬٠٠٠ | ١٤٥٬٠٠٠ | |||||
| 2016-04-15 | 2016-04-14 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | ٤٫١٤٣٤ | ٣٢٬٦٠٠ | ١٣٥ | ٥٣٬٠١٢ | ||||
| 2016-04-15 | 2016-04-14 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٤٫٢١٩٦ | ٣٣٬٦١٩ | ١٤٢ | ٢٨٣٬٥٨١ | ||||
| 2016-04-14 | 2016-04-13 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٣٫٨٥٠٠ | ٩٬٨٣٥ | ٣٨ | ٢٤٩٬٩٦٢ | ||||
| 2016-04-13 | 2016-04-11 | 4/A | SCHIMMEL PAUL | LIFE | Common Stock | I | ٣٫٥٩١٣ | ٢٢٬١٠٠ | ٧٩ | ٢٣٣٬٥٨١ | ||||
| 2016-04-13 | 2016-04-11 | 4/A | SCHIMMEL PAUL | LIFE | Common Stock | I | ٣٫٤٤٨١ | ٥٬٣٠٠ | ١٨ | ٢١١٬٤٨١ | ||||
| 2016-04-13 | 2016-04-11 | 4/A | SCHIMMEL PAUL | LIFE | Common Stock | D | ٣٫٥٩٢١ | ٥٬٢٥٩ | ١٩ | ١٧٬٨٣١ | ||||
| 2016-04-13 | 2016-04-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٣٫٦٩٩٩ | ٦٬٥٤٦ | ٢٤ | ٢٤٠٬١٢٧ | ||||
| 2016-04-13 | 2016-04-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | ٣٫٧٥١٢ | ٢٬٥٨١ | ١٠ | ٢٠٬٤١٢ | ||||
| 2016-04-12 | 2016-04-11 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | ٣٫٤٤٨١ | ٥٬٣٠٠ | ١٨ | ٢٢٠٬٢٣١ | ||||
| 2016-04-12 | 2016-04-11 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | ٣٫٥٩١٥ | ٢٧٬٣٥٩ | ٩٨ | ٢١٤٬٩٣١ | ||||
| 2016-04-11 | 2016-04-08 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | ٣٫٢١٩٤ | ٨٥٬٠٠٠ | ٢٧٤ | ١٨٧٬٥٧٢ | ||||
| 2016-04-08 | 2016-04-07 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | ٣٫١٨٩٦ | ٤٠٬٠٠٠ | ١٢٨ | ١٠٢٬٥٧٢ | ||||
| 2016-04-07 | 2016-04-05 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | ٣٫٥٢٠٠ | ٢٬٥٠٠ | ٩ | ٢٥٠٬٩٧١ | ||||
| 2016-04-07 | 2016-04-06 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | ٣٫٢٠٠٠ | ٢٥٬٠٠٠ | ٨٠ | ٦٢٬٥٧٢ | ||||
| 2016-04-06 | 2016-04-05 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | D | ٣٫٥٢٤٧ | ٢٥٬٠٠٠ | ٨٨ | ٣٧٬٥٧٢ | ||||
| 2016-04-06 | 2016-04-05 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | ٣٫٥٥٠٠ | ٢٬٥٠٠ | ٩ | ٢٤٨٬٤٧١ | ||||
| 2016-04-01 | 3 | Shukla Sanjay | LIFE | Common Stock | D | ٧٬٠٠٠ | ||||||||
| 2016-04-01 | 3 | Shukla Sanjay | LIFE | Common Stock | D | ٧٬٠٠٠ | ||||||||
| 2016-04-01 | 2016-03-30 | 4 | Shukla Sanjay | LIFE | Employee Stock Option (right to buy) | D | ٤٫٨٦ | ١٦٣٬٠٠٠ | ١٦٣٬٠٠٠ | |||||
| 2016-03-30 | 2016-03-28 | 4 | Blackburn Kelly | LIFE | Restricted Stock Unit | D | ٢١٬٦٠٠ | ٢١٬٦٠٠ | ||||||
| 2016-03-30 | 2016-03-28 | 4 | Cubitt Andrew | LIFE | Restricted Stock Unit | D | ١٣٬٠٠٠ | ١٣٬٠٠٠ | ||||||
| 2016-01-29 | 2016-01-27 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | ٦٫١٤ | ١٩٬٤٢٨ | ١٩٬٤٢٨ | |||||
| 2016-01-29 | 2016-01-27 | 4 | Goldberg Mark Alan | LIFE | Stock Option (right to buy) | D | ٦٫١٤ | ١٩٬٤٢٨ | ١٩٬٤٢٨ | |||||
| 2016-01-29 | 2016-01-27 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | ٦٫١٤ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2016-01-29 | 2016-01-27 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | ٦٫١٤ | ٨٬٥٠٠ | ٨٬٥٠٠ | |||||
| 2016-01-29 | 2016-01-27 | 4 | Ashlock Melissa A. | LIFE | Employee Stock Option (right to buy) | D | ٦٫١٤ | ١٨٬٢٥٠ | ١٨٬٢٥٠ | |||||
| 2016-01-29 | 2016-01-27 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | ٦٫١٤ | ٢٠٬٠٠٠ | ٢٠٬٠٠٠ | |||||
| 2016-01-29 | 2016-01-27 | 4 | Blackburn Stan | LIFE | Stock Option (right to buy) | D | ٦٫١٤ | ٤٬٢٥٠ | ٤٬٢٥٠ | |||||
| 2016-01-29 | 2016-01-27 | 4 | Blackburn Kelly | LIFE | Employee Stock Option (right to buy) | D | ٦٫١٤ | ١٨٬٢٥٠ | ١٨٬٢٥٠ | |||||
| 2016-01-29 | 2016-01-27 | 4 | Chrzanowski Holly D. | LIFE | Employee Stock Option (right to buy) | D | ٦٫١٤ | ٨٬٥٠٠ | ٨٬٥٠٠ | |||||
| 2016-01-29 | 2016-01-27 | 4 | AKKARAJU SRINIVAS | LIFE | Stock Option (right to buy) | D | ٦٫١٤ | ١٩٬٤٢٨ | ١٩٬٤٢٨ | |||||
| 2016-01-29 | 2016-01-27 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | ٦٫١٤ | ١٩٬٤٢٨ | ١٩٬٤٢٨ | |||||
| 2016-01-29 | 2016-01-27 | 4 | FALBERG KATHRYN E | LIFE | Stock Option (right to buy) | D | ٦٫١٤ | ١٩٬٤٢٨ | ١٩٬٤٢٨ | |||||
| 2016-01-29 | 2016-01-27 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | ٦٫١٤ | ١٩٬٤٢٨ | ١٩٬٤٢٨ | |||||
| 2016-01-29 | 2016-01-27 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | ٦٫١٤ | ١٣٥٬٠٠٠ | ١٣٥٬٠٠٠ | |||||
| 2016-01-29 | 2016-01-27 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | ٦٫١٤ | ١٩٬٤٢٨ | ١٩٬٤٢٨ | |||||
| 2016-01-29 | 2015-09-16 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ١١٬٩٢٥ | ٦٣٤٬٢٤٢ | ||||||
| 2016-01-29 | 2016-01-27 | 4 | McKew John C. | LIFE | Employee Stock Option (right to buy) | D | ٦٫١٤ | ٤٠٬٠٠٠ | ٤٠٬٠٠٠ | |||||
| 2016-01-06 | 2016-01-04 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | ٩٫١٣ | ١٤٨٬٧٣٢ | ١٤٨٬٧٣٢ | |||||
| 2016-01-06 | 2016-01-04 | 4 | McKew John C. | LIFE | Employee Stock Option (right to buy) | D | ٩٫١٣ | ٢٥٬٩١٣ | ٢٥٬٩١٣ | |||||
| 2016-01-06 | 2016-01-04 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | ٩٫١٣ | ١٠٬٨٣١ | ١٠٬٨٣١ | |||||
| 2016-01-06 | 2016-01-04 | 4 | Graham Marcy | LIFE | Employee Stock Option (right to buy) | D | ٩٫١٣ | ١٢٬٠٢٣ | ١٢٬٠٢٣ | |||||
| 2016-01-06 | 2016-01-04 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | ٩٫١٣ | ١٦٬٨٧٤ | ١٦٬٨٧٤ | |||||
| 2016-01-06 | 2016-01-04 | 4 | Chrzanowski Holly D. | LIFE | Employee Stock Option (right to buy) | D | ٩٫١٣ | ١٤٬٨٢٩ | ١٤٬٨٢٩ | |||||
| 2016-01-06 | 2016-01-04 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | ٩٫١٣ | ٥٬٠٣٨ | ٥٬٠٣٨ | |||||
| 2016-01-06 | 2016-01-04 | 4 | Blackburn Stan | LIFE | Employee Stock Option (right to buy) | D | ٩٫١٣ | ٥٬٧٥٤ | ٥٬٧٥٤ | |||||
| 2016-01-06 | 2016-01-04 | 4 | Blackburn Kelly | LIFE | Employee Stock Option (right to buy) | D | ٩٫١٣ | ٢٦٬٤٧٠ | ٢٦٬٤٧٠ | |||||
| 2016-01-06 | 2016-01-04 | 4 | Ashlock Melissa A. | LIFE | Employee Stock Option (right to buy) | D | ٩٫١٣ | ٢٩٬٦٥٩ | ٢٩٬٦٥٩ | |||||
| 2016-01-06 | 2016-01-04 | 4 | Ravindran Sanuj K. | LIFE | Employee Stock Option (right to buy) | D | ٩٫١٣ | ١٠٬٧٥٠ | ١٠٬٧٥٠ | |||||
| 2016-01-06 | 2016-01-04 | 4 | Ravindran Sanuj K. | LIFE | Employee Stock Option (right to buy) | D | ٩٫١٣ | ١٥٣٬٠٠٠ | ١٥٣٬٠٠٠ | |||||
| 2015-10-30 | 2015-10-28 | 4 | Blake John T | LIFE | Employee Stock Option (right to buy) | D | ١٢٫٤٩ | ٧٬٥٠٠ | ٧٬٥٠٠ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Ramsdell Fred | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٥٬٣٩٣ | ٥٬٣٩٣ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Ramsdell Fred | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ١٢٬٠٠٠ | ١٢٬٠٠٠ | |||||
| 2015-10-05 | 2015-10-01 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٦٥٬٠٧٠ | ٦٥٬٠٧٠ | |||||
| 2015-10-05 | 2015-10-01 | 4 | MENDLEIN JOHN | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٧١٬٠٠٠ | ٧١٬٠٠٠ | |||||
| 2015-10-05 | 2015-10-01 | 4 | McKew John C. | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ١١٬٣٣٧ | ١١٬٣٣٧ | |||||
| 2015-10-05 | 2015-10-01 | 4 | McKew John C. | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٢٣٬٠٠٠ | ٢٣٬٠٠٠ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٤٬٧٣٩ | ٤٬٧٣٩ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Krueger Nancy | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ١٧٬٠٠٠ | ١٧٬٠٠٠ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Graham Marcy | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٥٬٢٦٠ | ٥٬٢٦٠ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Graham Marcy | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٢٨٬٠٠٠ | ٢٨٬٠٠٠ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٧٬٣٨٢ | ٧٬٣٨٢ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Cubitt Andrew | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٢٣٬٠٠٠ | ٢٣٬٠٠٠ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Chrzanowski Holly D. | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٦٬٤٨٨ | ٦٬٤٨٨ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Chrzanowski Holly D. | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٢٤٬٠٠٠ | ٢٤٬٠٠٠ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Blackburn Stan | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٢٬٥١٨ | ٢٬٥١٨ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Blackburn Stan | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٩٬٥٠٠ | ٩٬٥٠٠ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Blackburn Kelly | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ١١٬٥٨١ | ١١٬٥٨١ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Blackburn Kelly | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٤٥٬٥٠٠ | ٤٥٬٥٠٠ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Ashlock Melissa A. | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ١٢٬٩٧٦ | ١٢٬٩٧٦ | |||||
| 2015-10-05 | 2015-10-01 | 4 | Ashlock Melissa A. | LIFE | Employee Stock Option (right to buy) | D | ١٠٫٢٤ | ٣٠٬٠٠٠ | ٣٠٬٠٠٠ | |||||
| 2015-07-10 | 2015-07-08 | 4 | Goldberg Mark Alan | LIFE | Stock Option (right to buy) | D | ١٤٫٩٦ | ٦٬٢٨٦ | ٦٬٢٨٦ | |||||
| 2015-07-10 | 2015-07-08 | 4 | SCHIMMEL PAUL | LIFE | Stock Option (right to buy) | D | ١٤٫٩٦ | ٦٬٢٨٦ | ٦٬٢٨٦ | |||||
| 2015-07-10 | 2015-07-08 | 4 | CLARKE JOHN K | LIFE | Stock Option (right to buy) | D | ١٤٫٩٦ | ٦٬٢٨٦ | ٦٬٢٨٦ | |||||
| 2015-07-10 | 2015-07-08 | 4 | Nashat Amir | LIFE | Stock Option (right to buy) | D | ١٤٫٩٦ | ٦٬٢٨٦ | ٦٬٢٨٦ | |||||
| 2015-07-10 | 2015-07-08 | 4 | BLAIR JAMES C | LIFE | Stock Option (right to buy) | D | ١٤٫٩٦ | ٦٬٢٨٦ | ٦٬٢٨٦ | |||||
| 2015-07-10 | 2015-07-08 | 4 | AKKARAJU SRINIVAS | LIFE | Stock Option (right to buy) | D | ١٤٫٩٦ | ٦٬٢٨٦ | ٦٬٢٨٦ | |||||
| 2015-07-10 | 2015-07-08 | 4 | FALBERG KATHRYN E | LIFE | Stock Option (right to buy) | D | ١٤٫٩٦ | ٦٬٢٨٦ | ٦٬٢٨٦ | |||||
| 2015-05-14 | 3/A | SCHIMMEL PAUL | LIFE | Common Stock | D | ١٢٬٥٧٢ | ||||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series E Redeemable Convertible Preferred Stock | I | ٤٤٦٬٨٢٧ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series D Redeemable Convertible Preferred Stock | I | ١٥٬٠٣١ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series C Redeemable Convertible Preferred Stock | I | ٥٥٨٬٥٠٨ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | ١٬٤٤٠٬٠٥٨ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series B Redeemable Convertible Preferred Stock | I | ١٬٢٠٠٬٠٠٠ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series A Redeemable Convertible Preferred Stock | I | ٥٢٥٬٠٠٠ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Series D Redeemable Convertible Preferred Stock | I | ٢٤٨٬٠٢٤ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٤٦٬١٥٢ | ٦٤٦٬١٦٧ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٤٧٠٬٠٢٠ | ٦٠٠٬٠١٥ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | SCHIMMEL PAUL | LIFE | Common Stock | I | ٣١٬١٨١ | ٣١٬١٨١ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | AKKARAJU SRINIVAS By Sofinnova Venture Partners IX, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | ١٤٬٩٦٨٬٧٢٢ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | AKKARAJU SRINIVAS By Sofinnova Venture Partners IX, L.P. | LIFE | Common Stock | I | ١٤٫٠٠٠٠ | ٣٢٠٬٠٠٠ | ٤٬٤٨٠ | ١٬٨٦٦٬١٢٦ | ||||
| 2015-05-14 | 2015-05-12 | 4 | AKKARAJU SRINIVAS By Sofinnova Venture Partners IX, L.P. | LIFE | Common Stock | I | ١٬٥٤٦٬١٢٦ | ١٬٥٤٦٬١٢٦ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | MENDLEIN JOHN | LIFE | Series D Redeemable Convertible Preferred Stock | D | ٢١٬١٢٢ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | MENDLEIN JOHN | LIFE | Series C Redeemable Convertible Preferred Stock | D | ١٧٠٬٢١٨ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | MENDLEIN JOHN | LIFE | Common Stock | D | ٢٤٬٠٥٥ | ٢٤٥٬٩٧١ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series D Redeemable Convertible Preferred Stock | I | ١٬٥٣٦٬٧٨٧ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series C Redeemable Convertible Preferred Stock | I | ٢٬١٢٧٬٦٦٠ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | ٤٬٣٢٠٬١٧٣ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series B Redeemable Convertible Preferred Stock | I | ٣٬٦٠٠٬٠٠٠ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series A Redeemable Convertible Preferred Stock | I | ٢٬٤٠٠٬٠٠٠ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Series E Redeemable Convertible Preferred Stock | D | ٨٩٣٬٦٥٥ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Common Stock | I | ١٬٧٥٨٬١٥٨ | ١٬٧٥٨٬١٥٨ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CLARKE JOHN K | LIFE | Common Stock | D | ٩٢٬٣٠٦ | ١٠٤٬٨٧٨ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | D | ٨٩٣٬٦٥٥ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | D | ١٬١٢٦٬٨٦٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | D | ٤٬٣٦١٬٧٠٣ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | D | ٤٬٣٢٠٬١٧٣ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | D | ٣٬٦٠٠٬٠٠٠ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Common Stock | D | ٩٢٬٣٠٦ | ١٬٧٧٨٬٠٦٤ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Alta Partners VIII, L.P. | LIFE | Common Stock | D | ١٬٦٨٥٬٧٥٨ | ١٬٦٨٥٬٧٥٨ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series D Redeemable Convertible Preferred Stock | D | ١٬٥٣٦٬٧٨٧ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series C Redeemable Convertible Preferred Stock | D | ٢٬١٢٧٬٦٦٠ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series B-2 Redeemable Convertible Preferred Stock | D | ٤٬٣٢٠٬١٧٣ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series B Redeemable Convertible Preferred Stock | D | ٣٬٦٠٠٬٠٠٠ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Series A Redeemable Convertible Preferred Stock | D | ٢٬٤٠٠٬٠٠٠ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | CHP II LP | LIFE | Common Stock | D | ١٬٧٥٨٬١٥٨ | ١٬٧٥٨٬١٥٨ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | ٨٬٦٢٣ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | ٥٬٩٠٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | ١٦٬٨٠٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | ٨٦٢٬٣١٨ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | ١٤٬٧٠٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | ١٠٬٠٧٤ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | ٢٨٬٦٦١ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | ١٬٤٧٠٬٥٧٧ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | ٤٢٬٠٨٧ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | ٢٨٬٨٣١ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | ٨٢٬٠٢٩ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | ٤٬٢٠٨٬٧٥٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | ٤١٬٦٨٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | ٢٨٬٥٥٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | ٨١٬٢٤٨ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | ٤٬١٦٨٬٦٨٣ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | ٣٤٬٧٣٧ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | ٢٣٬٧٩٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | ٦٧٬٧٠٤ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | ٣٬٤٧٣٬٧٦٣ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Common Stock | I | ٨٩٠ | ١٧٬٦٣٨ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Common Stock | I | ٦١٠ | ١٢٬٠٨٢ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Common Stock | I | ١٬٧٣٦ | ٣٤٬٣٧٨ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Common Stock | I | ٨٩٬٠٦٩ | ١٬٧٦٣٬٨٩٤ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Common Stock | I | ١٦٬٧٤٨ | ١٦٬٧٤٨ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Common Stock | I | ١١٬٤٧٢ | ١١٬٤٧٢ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Common Stock | I | ٣٢٬٦٤٢ | ٣٢٬٦٤٢ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Polaris Venture Management Co. V, L.L.C. By Polaris Venture Partners V, L.P. | LIFE | Common Stock | I | ١٬٦٧٤٬٨٢٥ | ١٬٦٧٤٬٨٢٥ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | ٨٬٦٢٣ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | ٥٬٩٠٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | ١٦٬٨٠٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | I | ٨٦٢٬٣١٨ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | ١٤٬٧٠٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | ١٠٬٠٧٤ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | ٢٨٬٦٦١ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series D Redeemable Convertible Preferred Stock | I | ١٬٤٧٠٬٥٧٧ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | ٤٢٬٠٨٧ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | ٢٨٬٨٣١ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | ٨٢٬٠٢٩ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series C Redeemable Convertible Preferred Stock | I | ٤٬٢٠٨٬٧٥٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | ٤١٬٦٨٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | ٢٨٬٥٥٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | ٨١٬٢٤٨ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series B-2 Redeemable Convertible Preferred Stock | I | ٤٬١٦٨٬٦٨٣ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | ٣٤٬٧٣٧ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | ٢٣٬٧٩٦ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | ٦٧٬٧٠٤ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Series B Redeemable Convertible Preferred Stock | I | ٣٬٤٧٣٬٧٦٣ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Common Stock | I | ٨٩٠ | ١٧٬٦٣٨ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Common Stock | I | ٦١٠ | ١٢٬٠٨٢ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Common Stock | I | ١٬٧٣٦ | ٣٤٬٣٧٨ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Common Stock | I | ٨٩٬٠٦٩ | ١٬٧٦٣٬٨٩٤ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir Polaris Venture Partners Special Founders' Fund V, L.P. | LIFE | Common Stock | I | ١٦٬٧٤٨ | ١٦٬٧٤٨ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Founders' Fund V, L.P. | LIFE | Common Stock | I | ١١٬٤٧٢ | ١١٬٤٧٢ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners Entrepreneurs' Fund V, L.P. | LIFE | Common Stock | I | ٣٢٬٦٤٢ | ٣٢٬٦٤٢ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Nashat Amir By Polaris Venture Partners V, L.P. | LIFE | Common Stock | I | ١٬٦٧٤٬٨٢٥ | ١٬٦٧٤٬٨٢٥ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Sofinnova Venture Partners IX, L.P. | LIFE | Series E Redeemable Convertible Preferred Stock | D | ١٤٬٩٦٨٬٧٢٢ | ٠ | ||||||
| 2015-05-14 | 2015-05-12 | 4 | Sofinnova Venture Partners IX, L.P. | LIFE | Common Stock | D | ١٤٫٠٠٠٠ | ٣٢٠٬٠٠٠ | ٤٬٤٨٠ | ١٬٨٦٦٬١٢٦ | ||||
| 2015-05-14 | 2015-05-12 | 4 | Sofinnova Venture Partners IX, L.P. | LIFE | Common Stock | D | ١٬٥٤٦٬١٢٦ | ١٬٥٤٦٬١٢٦ | ||||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | LIFE | Series E Preferred Stock | I | ٢٬٢٣٤٬١٣٧ | ٠ | ||||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | LIFE | Series E Preferred Stock | I | ٢٬٢٣٤٬١٣٧ | ٠ | ||||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | LIFE | Common Stock | I | ١٤٫٠٠٠٠ | ٢٥٬٠٠٠ | ٣٥٠ | ٢٥٥٬٧٦٤ | ||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | LIFE | Common Stock | I | ١٤٫٠٠٠٠ | ٢٥٬٠٠٠ | ٣٥٠ | ٢٥٥٬٧٦٤ | ||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | LIFE | Common Stock | I | ٢٣٠٬٧٦٤ | ٢٣٠٬٧٦٤ | ||||||
| 2015-05-13 | 2015-05-12 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | LIFE | Common Stock | I | ٢٣٠٬٧٦٤ | ٢٣٠٬٧٦٤ | ||||||
| 2015-05-12 | 2015-05-12 | 4 | DP VIII Associates, L.P. | LIFE | Series E Preferred Stock | D | ٦٬٥٨١ | ٠ | ||||||
| 2015-05-12 | 2015-05-12 | 4 | DP VIII Associates, L.P. | LIFE | Series D Preferred Stock | D | ١١٬١٨٢ | ٠ | ||||||
| 2015-05-12 | 2015-05-12 | 4 | DP VIII Associates, L.P. | LIFE | Series C Preferred Stock | D | ٩٠٬١١٠ | ٠ | ||||||
| 2015-05-12 | 2015-05-12 | 4 | DP VIII Associates, L.P. | LIFE | Common Stock | D | ١٣٬٤١٤ | ١٣٬٤١٤ | ||||||
| 2015-05-12 | 2015-05-12 | 4 | Domain Partners VIII, L.P. | LIFE | Series E Preferred Stock | D | ٨٨٧٬٠٧٣ | ٠ | ||||||
| 2015-05-12 | 2015-05-12 | 4 | Domain Partners VIII, L.P. | LIFE | Series D Preferred Stock | D | ١٬٥٠٦٬٩٠١ | ٠ | ||||||
| 2015-05-12 | 2015-05-12 | 4 | Domain Partners VIII, L.P. | LIFE | Series C Preferred Stock | D | ١٢٬١٤٣٬٩٣٣ | ٠ | ||||||
| 2015-05-12 | 2015-05-12 | 4 | Domain Partners VIII, L.P. | LIFE | Common Stock | D | ١٬٨٠٧٬٨٢٠ | ١٬٨٠٧٬٨٢٠ | ||||||
| 2015-05-08 | 2015-05-06 | 4 | MENDLEIN JOHN | LIFE | Stock Option (right to buy) | D | ١٤٫٠٠ | ١٦٣٬٤٣٧ | ١٦٣٬٤٣٧ | |||||
| 2015-05-08 | 2015-05-06 | 4 | Ramsdell Fred | LIFE | Stock Option (right to buy) | D | ١٤٫٠٠ | ١٧٬٦٠٠ | ١٧٬٦٠٠ | |||||
| 2015-05-08 | 2015-05-06 | 4 | Chrzanowski Holly D. | LIFE | Stock Option (right to buy) | D | ١٤٫٠٠ | ١١٬٩٤٣ | ١١٬٩٤٣ | |||||
| 2015-05-08 | 2015-05-06 | 4 | McKew John C. | LIFE | Stock Option (right to buy) | D | ١٤٫٠٠ | ٢٥٬١٤٤ | ٢٥٬١٤٤ | |||||
| 2015-05-08 | 2015-05-06 | 4 | Blackburn Kelly | LIFE | Stock Option (right to buy) | D | ١٤٫٠٠ | ٣٤٬٥٧٣ | ٣٤٬٥٧٣ | |||||
| 2015-05-08 | 2015-05-06 | 4 | Blackburn Stan | LIFE | Stock Option (right to buy) | D | ١٤٫٠٠ | ٤٬٠٨٥ | ٤٬٠٨٥ | |||||
| 2015-05-08 | 2015-05-06 | 4 | Chereau Frederic | LIFE | Stock Option (right to buy) | D | ١٤٫٠٠ | ٢٢٬٠٠١ | ٢٢٬٠٠١ | |||||
| 2015-05-08 | 2015-05-06 | 4 | Graham Marcy | LIFE | Stock Option (right to buy) | D | ١٤٫٠٠ | ١٠٬٦٨٦ | ١٠٬٦٨٦ | |||||
| 2015-05-08 | 2015-05-06 | 4 | Krueger Nancy | LIFE | Stock Option (right to buy) | D | ١٤٫٠٠ | ٨٬٨٠٠ | ٨٬٨٠٠ | |||||
| 2015-05-08 | 2015-05-06 | 4 | Ashlock Melissa A. | LIFE | Stock Option (right to buy) | D | ١٤٫٠٠ | ٢٥٬١٤٤ | ٢٥٬١٤٤ | |||||
| 2015-05-08 | 2015-05-06 | 4 | Weiner David M. | LIFE | Stock Option (right to buy) | D | ١٤٫٠٠ | ٤٤٬٠٠٢ | ٤٤٬٠٠٢ | |||||
| 2015-05-08 | 2015-05-06 | 4 | Cubitt Andrew | LIFE | Stock Option (right to buy) | D | ١٤٫٠٠ | ٥٬٦٥٧ | ٥٬٦٥٧ | |||||
| 2015-05-06 | 3 | FALBERG KATHRYN E | LIFE | Common Stock | D | ٢٥٬١٤٤ | ||||||||
| 2015-05-06 | 3 | FALBERG KATHRYN E | LIFE | Common Stock | D | ٢٥٬١٤٤ | ||||||||
| 2015-05-06 | 3 | Nashat Amir | LIFE | Common Stock | D | ٢٥٬١٤٤ | ||||||||
| 2015-05-06 | 3 | Nashat Amir | LIFE | Common Stock | D | ٢٥٬١٤٤ | ||||||||
| 2015-05-06 | 3 | Ashlock Melissa A. | LIFE | Common Stock | D | ١٣٦٬٣٢٨ | ||||||||
| 2015-05-06 | 3 | Ashlock Melissa A. | LIFE | Common Stock | D | ١٣٦٬٣٢٨ | ||||||||
| 2015-05-06 | 3 | SCHIMMEL PAUL By Schimmel Revocable Trust U/A Dtd 9/6/2000 | LIFE | Common Stock | I | ٢٦٩٬٤١٩ | ||||||||
| 2015-05-06 | 3 | SCHIMMEL PAUL | LIFE | Common Stock | D | ١٤٨٬٨٥٣ | ||||||||
| 2015-05-06 | 3 | SCHIMMEL PAUL | LIFE | Common Stock | D | ١٤٨٬٨٥٣ | ||||||||
| 2015-05-06 | 3 | SCHIMMEL PAUL By Schimmel Revocable Trust U/A Dtd 9/6/2000 | LIFE | Common Stock | I | ٢٦٩٬٤١٩ | ||||||||
| 2015-05-06 | 3 | CLARKE JOHN K | LIFE | Common Stock | D | ٢٥٬١٤٤ | ||||||||
| 2015-05-06 | 3 | CLARKE JOHN K | LIFE | Common Stock | D | ٢٥٬١٤٤ | ||||||||
| 2015-05-06 | 3 | MENDLEIN JOHN | LIFE | Common Stock | D | ٤٤٣٬٨٣٢ | ||||||||
| 2015-05-06 | 3 | MENDLEIN JOHN | LIFE | Common Stock | D | ٤٤٣٬٨٣٢ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Kamdar Kim P. | LIFE | Common Stock | D | ١٨٬٨٥٨ | ||||||||
| 2015-05-06 | 3 | Chrzanowski Holly D. | LIFE | Common Stock | D | ٣٬٧٧٠ | ||||||||
| 2015-05-06 | 3 | Chrzanowski Holly D. | LIFE | Common Stock | D | ٣٬٧٧٠ | ||||||||
| 2015-05-06 | 3 | Blackburn Kelly | LIFE | Common Stock | D | ٥٥٨ | ||||||||
| 2015-05-06 | 3 | Blackburn Kelly | LIFE | Common Stock | D | ٥٥٨ | ||||||||
| 2015-05-06 | 3 | Chereau Frederic | LIFE | Common Stock | D | ٢٥٬٧٣٤ | ||||||||
| 2015-05-06 | 3 | Chereau Frederic | LIFE | Common Stock | D | ٢٥٬٧٣٤ | ||||||||
| 2015-05-06 | 3 | Blackburn Stan By the J. Stanhope Blackburn and Karlene S. Blackburn Family Trust U.T.D. May 9, 2001 | LIFE | Common Stock | I | ١٨٩٬٩٥١ | ||||||||
| 2015-05-06 | 3 | Blackburn Stan | LIFE | Common Stock | D | ٩٨٬١٩٩ | ||||||||
| 2015-05-06 | 3 | Blackburn Stan By the J. Stanhope Blackburn and Karlene S. Blackburn Family Trust U.T.D. May 9, 2001 | LIFE | Common Stock | I | ١٨٩٬٩٥١ | ||||||||
| 2015-05-06 | 3 | Blackburn Stan | LIFE | Common Stock | D | ٩٨٬١٩٩ | ||||||||
| 2015-05-06 | 3 | Weiner David M. | LIFE | Common Stock | D | ١٠٬٠٥٦ | ||||||||
| 2015-05-06 | 3 | Weiner David M. | LIFE | Common Stock | D | ١٠٬٠٥٦ |
P
السوق المفتوحة أو الشراء الخاص للأوراق المالية غير المشتقة أو المشتقة
S
السوق المفتوحة أو البيع الخاص للأوراق المالية غير المشتقة أو المشتقة
A
المنح أو المكافأة أو الاستحواذ على الأوراق المالية من الشركة (مثل الخيار)
C
تحويل المشتقات
D
بيع أو نقل الأوراق المالية مرة أخرى إلى الشركة
F
دفع سعر التمرين أو الالتزام الضريبي باستخدام جزء من الأوراق المالية المستلمة من الشركة
G
هدية الأوراق المالية من قبل أو إلى المطلعين
K
مقايضات الأسهم ومعاملات التحوط المماثلة
M
التمرين أو تحويل الأوراق المالية المشتقة المستلمة من الشركة (مثل الخيار)
V
معاملة تم الإبلاغ عنها طوعًا في النموذج 4
J
أخرى (مصحوبة بحاشية تصف المعاملة)
