ALT / Altimmune, Inc. - تصريحات هيئة الأوراق المالية والبورصات، التقرير السنوي، بيان الوكيل

شركة ألتيمون
US ˙ NasdaqGM ˙ US02155H2004

الإحصائيات الأساسية
LEI 549300EOYCQ8SW3NVE64
CIK 1326190
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Altimmune, Inc.
SEC Filings (Chronological Order)
توفر هذه الصفحة قائمة كاملة ومرتبة ترتيبًا زمنيًا لتصريحات هيئة الأوراق المالية والبورصات، باستثناء تصريحات الملكية التي نقدمها في مكان آخر.
August 15, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.  )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 1

August 15, 2025 ARS

ARS

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 or ☐ ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-32587 ALTIMMUNE,

August 12, 2025 EX-99.1

Altimmune Announces Second Quarter 2025 Financial Results and Business Update Positive data from the IMPACT Phase 2b trial reinforces the potential for pemvidutide to be a highly differentiated MASH therapy Pemvidutide is the first product candidate

Exhibit 99.1 Altimmune Announces Second Quarter 2025 Financial Results and Business Update Positive data from the IMPACT Phase 2b trial reinforces the potential for pemvidutide to be a highly differentiated MASH therapy Pemvidutide is the first product candidate to achieve statistically significant MASH resolution and weight loss at 24 weeks New data from the IMPACT trial demonstrates potentially

August 12, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001

August 12, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2025 ALTIMMUNE, INC. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2025 ALTIMMUNE, INC.

June 26, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 2025 ALTIMMUNE, INC. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 2025 ALTIMMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File Numb

June 26, 2025 EX-99.2

1.2 mg weekly* 1.8 mg weekly* Placebo weekly Week 48 NITs Weight Loss Week 24 Liver Biopsy NITs Weight Loss Screening/Randomization IMPACT Phase 2b MASH Trial Key Eligibility Criteria • MASH (F2/F3) • LFC† ≥ 8% • BMI ≥ 27.0 kg/m2 † liver fat content

Exhibit 99.2 IMPACT Phase 2b MASH Trial - Topline Results Pemvidutide: Designed to be the Treatment of Choice for Liver and Cardiometabolic Diseases J u n e 2 6 , 2 0 2 5 Company Confidential Forward-looking statements Safe-Harbor Statement This presentation has been prepared by Altimmune, Inc. ("we," "us," "our," "Altimmune" or the "Company") and includes certain “forward-looking statements” with

June 26, 2025 EX-99.1

Altimmune Announces Positive Topline Results from the IMPACT Phase 2b Trial of Pemvidutide in the Treatment of MASH First product candidate to demonstrate significant MASH effects and weight loss at 24 weeks Trial met its primary endpoint with statis

Exhibit 99.1 Altimmune Announces Positive Topline Results from the IMPACT Phase 2b Trial of Pemvidutide in the Treatment of MASH First product candidate to demonstrate significant MASH effects and weight loss at 24 weeks Trial met its primary endpoint with statistically significant MASH resolution without worsening of fibrosis in up to 59.1% of participants in an ITT analysis Fibrosis improvement

May 13, 2025 EX-99.2

Altimmune Secures Up to $100 Million in Credit Facility from Hercules Capital Term loan adds balance sheet strength and provides financial flexibility to support continued development of pemvidutide

Exhibit 99.2 Altimmune Secures Up to $100 Million in Credit Facility from Hercules Capital Term loan adds balance sheet strength and provides financial flexibility to support continued development of pemvidutide GAITHERSBURG, MD – May 13, 2025 – Altimmune, Inc. (Nasdaq: ALT), a late clinical-stage biopharmaceutical company developing novel peptide-based therapeutics for liver and cardiometabolic d

May 13, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 13, 2025 ALTIMMUNE, INC. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 13, 2025 ALTIMMUNE, INC.

May 13, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 00

May 13, 2025 EX-99.1

Altimmune Announces First Quarter 2025 Financial Results and Business Update Top-line data from IMPACT Phase 2b trial of pemvidutide in metabolic dysfunction-associated steatohepatitis (MASH) expected in Q2 2025 Phase 2 trials in Alcohol Use Disorder

Exhibit 99.1 Altimmune Announces First Quarter 2025 Financial Results and Business Update Top-line data from IMPACT Phase 2b trial of pemvidutide in metabolic dysfunction-associated steatohepatitis (MASH) expected in Q2 2025 Phase 2 trials in Alcohol Use Disorder (AUD) and Alcohol Liver Disease (ALD), expected to initiate in Q2 and Q3 2025, respectively Cash, cash equivalents and short-term invest

May 13, 2025 EX-10.3

Loan and Security Agreement, dated May 13, 2025, by and between Altimmune, Inc. and Hercules Capital, Inc.

Exhibit 10.3 CERTAIN INFORMATION IN THIS DOCUMENT, MARKED BY [***], HAS BEEN EXCLUDED PURSUANT TO REGULATION S-K, ITEM 601(b)(10)(iv). SUCH EXCLUDED INFORMATION IS NOT MATERIAL AND IS THE TYPE THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL. LOAN AND SECURITY AGREEMENT THIS LOAN AND SECURITY AGREEMENT is made and dated as of May 13, 2025 and is entered into by and among Altimmune, Inc., a De

March 13, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 13, 2025 ALTIMMUNE, INC. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 13, 2025 ALTIMMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File Num

March 11, 2025 CORRESP

Altimmune, Inc. 910 Clopper Road, Suite 201S Gaithersburg, Maryland 20878

Altimmune, Inc. 910 Clopper Road, Suite 201S Gaithersburg, Maryland 20878 March 11, 2025 Via EDGAR United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Re: Altimmune, Inc.: Registration Statement on Form S-3, filed February 27, 2025 (File No. 333- 285355) Ladies and Gentlemen: Pursuant to Rule 461 under t

February 27, 2025 S-8

As filed with the Securities and Exchange Commission on February 27, 2025

As filed with the Securities and Exchange Commission on February 27, 2025 Registration No.

February 27, 2025 S-3

As filed with the Securities and Exchange Commission on February 27, 2025

Table of Contents As filed with the Securities and Exchange Commission on February 27, 2025 Registration No.

February 27, 2025 EX-10.15

Consulting Agreement, dated February 6, 2025, by and between Altimmune, Inc. and Catherine Sohn

Exhibit 10.15 ALTIMMUNE, INC. CONSULTING AGREEMENT This Consulting Agreement (the “Agreement”) is hereby made and entered into as of January 15, 2025 (the “Effective Date”), by and between Altimmune, Inc. and its Affiliates, a Delaware corporation (“Altimmune”), having a place of business at 910 Clopper Road, Suite 201- S, Gaithersburg, Maryland 20878 and Catherine Sohn (“Consultant”). 1.Engagemen

February 27, 2025 EX-4.1

Description of Registrant’s Securities

Exhibit 4.1 Description of the Registrant’s Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934, as amended The summary of the general terms and provisions of the registered securities of Altimmune, Inc. (“Altimmune” “we,” or “our”) set forth below does not purport to be complete and is subject to and qualified in its entirety by reference to our Amended and Restate

February 27, 2025 EX-1.2

Equity Distribution Agreement, dated as of February 27, 2025 among the Registrant and Leerink Partners LLC, Piper Sandler & Co. and Stifel, Nicolaus & Company, Incorporated

Exhibit 1.2 ALTIMMUNE, INC. EQUITY DISTRIBUTION AGREEMENT February 27, 2025 LEERINK PARTNERS LLC 1301 Avenue of the Americas, 5th Floor New York, New York 10019 PIPER SANDLER & CO. 1251 Avenue of the Americas, 39th Floor New York, New York 10020 STIFEL, NICOLAUS & COMPANY, INCORPORATED 787 7th Avenue, 11th Floor New York, New York 10019 Ladies and Gentlemen: As further set forth in this agreement

February 27, 2025 EX-10.7

Altimmune, Inc. Non-Employee Director Compensation Policy

Exhibit 10.7 ALTIMMUNE, INC. NON-EMPLOYEE DIRECTOR COMPENSATION POLICY The purpose of this Director Compensation Policy of Altimmune, Inc. (the “Company”), is to provide a total compensation package that enables the Company to attract and retain, on a long-term basis, high-caliber directors who are not employees or officers of the Company or its subsidiaries. In furtherance of the purpose stated a

February 27, 2025 10-K

2024 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-32

February 27, 2025 EX-21

SIGNIFICANT SUBSIDIARIES

Exhibit 21 SIGNIFICANT SUBSIDIARIES List of Subsidiaries Jurisdiction of Incorporation or Organization Altimmune, LLC (1) Delaware Altimmune UK, Limited (1) United Kingdom Spitfire Pharma, LLC (1) Delaware Altimmune AU Pty, Limited (1) Australia (1) Wholly owned subsidiary of the Company

February 27, 2025 EX-FILING FEES

Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Altimmune, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered (1) Proposed Maximum Offering Price Per Unit (2) Maximum Aggregate Offering Price Fee Rate (5) Amount of Registration

February 27, 2025 EX-99.1

Altimmune Announces Fourth Quarter and Full Year 2024 Financial Results and Provides a Business Update Top-line data from Phase 2b IMPACT trial of pemvidutide in metabolic dysfunction-associated steatohepatitis (MASH) to be reported in Q2 2025 Invest

Exhibit 99.1 Altimmune Announces Fourth Quarter and Full Year 2024 Financial Results and Provides a Business Update Top-line data from Phase 2b IMPACT trial of pemvidutide in metabolic dysfunction-associated steatohepatitis (MASH) to be reported in Q2 2025 Investigational New Drug (IND) applications in two additional indications have received FDA clearance, with Phase 2 trials to commence mid-2025

February 27, 2025 EX-19

Insider Trading Policies and Procedures

Exhibit 19 ALTIMMUNE, INC. AMENDED AND RESTATED INSIDER TRADING POLICY Altimmune, Inc. (the “Company”) has adopted the following amended and restated policy and procedures for securities trading by Company directors and employees (our “Insider Trading Policy”). Our Insider Trading Policy is intended to prevent the misuse of material nonpublic information, insider trading in securities, and the sev

February 27, 2025 EX-5.5

Consent of Goodwin Procter LLP (included in Exhibit 5.1)

Exhibit 5.1 Goodwin Procter llp 100 Northern Avenue Boston, MA 02210 goodwinlaw.com +1 617 570 1000 February 27, 2025 Altimmune, Inc. 910 Clopper Road Suite 201S, Gaithersburg, MD 20878 Re: Securities Being Registered under Registration Statement on Form S-3 We have acted as counsel to you in connection with your filing of a Registration Statement on Form S-3 (as amended or supplemented, the “Regi

February 27, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 24, 2025 ALTIMMUNE, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 24, 2025 ALTIMMUNE, INC.

February 27, 2025 EX-4.5

Form of Subordinated Indenture between Registrant and one or more trustees to be named

Exhibit 4.5 ALTIMMUNE INC., Issuer AND [TRUSTEE], Trustee INDENTURE Dated as of [ ], 2025 Subordinated Debt Securities TABLE OF CONTENTS! ARTICLE 1 DEFINITIONS Section 1.01 Definitions of Terms ARTICLE 2 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.01 Designation and Terms of Securities 4 Section 2.02 Form of Securities and Trustee's Certificate 6 Secti

February 27, 2025 EX-FILING FEES

Filing Fee Table

EXHIBIT 107.1 Calculation of Filing Fee Table Form S-8 (Form Type) Altimmune, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1 - Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Share(2) Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Common stock, $0.0001 par

February 27, 2025 EX-4.4

Form of Senior Indenture between Registrant and one or more trustees to be named

Exhibit 4.4 Altimmune Inc. Issuer AND [TRUSTEE], Trustee INDENTURE Dated as of [ ], 2025 Senior Debt Securities TABLE OF CONTENTS! ARTICLE 1 DEFINITIONS Section 1.01 Definitions of Terms ARTICLE 2 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.0I Designation and Terms of Securities 4 Section 2.02 Form of Securities and Trustee's Certificate 6 Section 2.03

February 25, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 24, 2025 ALTIMMUNE, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 24, 2025 ALTIMMUNE, INC.

February 25, 2025 EX-99.1

Seasoned Biopharmaceutical Industry Executives Teri Lawver and Jerry Durso Appointed to Altimmune Board of Directors Ms. Lawver, former Chief Commercial Officer of Dexcom and Global Vice President at Johnson & Johnson responsible for billion-dollar I

Exhibit 99.1 Seasoned Biopharmaceutical Industry Executives Teri Lawver and Jerry Durso Appointed to Altimmune Board of Directors Ms. Lawver, former Chief Commercial Officer of Dexcom and Global Vice President at Johnson & Johnson responsible for billion-dollar Immunology and Cardiovascular & Metabolism Portfolios over her 20-year career Mr. Durso led biopharmaceutical company focused on liver dis

December 11, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 15, 2024 ALTIMMUNE, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 15, 2024 ALTIMMUNE, INC.

November 14, 2024 EX-99.I

to Schedule 13G

EX-99.I Exhibit I to Schedule 13G Ameriprise Financial, Inc., a Delaware Corporation, is a parent holding company. The classification and identity of the relevant subsidiaries is as follows: Non-US Institution – TAM UK International Holdings Limited, a private limited company incorporated in England and Wales, is a holding company and parent entity to Threadneedle Holdings Limited. Non-US Institut

November 14, 2024 EX-99.III

to Schedule 13G Powers of Attorney LIMITED POWER OF ATTORNEY

EX-99.III Exhibit III to Schedule 13G Powers of Attorney LIMITED POWER OF ATTORNEY KNOW ALL MEN BY THESE PRESENTS, which are intended to constitute a Limited Power of Attorney, that TAM UK International Holdings Limited, a company incorporated under the laws of England and Wales under registered number 12728685, with its principal place of business at Cannon Place, 78 Cannon Street, London, EC4N 6

November 14, 2024 SC 13G/A

ALT / Altimmune, Inc. / AMERIPRISE FINANCIAL INC - SC 13G/A Passive Investment

SC 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Amendment #1 Under the Securities and Exchange Act of 1934 Altimmune, Inc (Name of Issuer) Common Stock (Title of Class of Securities) 02155H200 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is fi

November 14, 2024 EX-99.II

to Schedule 13G Joint Filing Agreement

EX-99.II Exhibit II to Schedule 13G Joint Filing Agreement The undersigned persons agree and consent to the joint filing on their behalf of this Schedule 13G dated November 14, 2024 in connection with their beneficial ownership of Altimmune, Inc. Each of TAM UK International Holdings Limited, Threadneedle Holdings Limited, TAM UK Holdings Limited, Threadneedle Asset Management Holdings Limited, TC

November 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 ALTIMMUNE, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 ALTIMMUNE, INC.

November 12, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numbe

November 12, 2024 EX-99.1

Altimmune Appoints Life Sciences Industry Veteran Greg Weaver as Chief Financial Officer

Exhibit 99.1 Altimmune Appoints Life Sciences Industry Veteran Greg Weaver as Chief Financial Officer GAITHERSBURG, MD – November 11, 2024 – Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced the appointment of Greg Weaver as Chief Financial Officer (CFO), effective immediately. Mr. Weaver will lead the Company’s finance and accounting functions, including S

November 12, 2024 EX-10.1

Employment Agreement, dated November 6, 2024, by and between Altimmune, Inc. and Gregory Weaver (incorporated by reference to Exhibit 10.1 to the Registrant’s Form 8-K filed on November 12, 2024)

Exhibit 10.1 EMPLOYMENT AGREEMENT This EMPLOYMENT AGREEMENT (“Agreement”) is made and entered into as of November 6, 2024, by and between Greg Weaver (“Executive”) and Altimmune, Inc., a Delaware corporation (“Altimmune”). WHEREAS, the Board of Directors of Altimmune (the “Board”) desires to employ Executive, and Executive desires to be employed by Altimmune pursuant to the terms and conditions se

November 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 11, 2024 ALTIMMUNE, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 11, 2024 ALTIMMUNE, INC.

November 12, 2024 EX-99.1

Altimmune Announces Third Quarter 2024 Financial Results and Provides a Business Update Enrollment completed in Phase 2b IMPACT trial of pemvidutide in metabolic dysfunction-associated steatohepatitis (MASH); top-line efficacy data expected in Q2 202

Exhibit 99.1 Altimmune Announces Third Quarter 2024 Financial Results and Provides a Business Update Enrollment completed in Phase 2b IMPACT trial of pemvidutide in metabolic dysfunction-associated steatohepatitis (MASH); top-line efficacy data expected in Q2 2025 Successful completion of the obesity End-of-Phase 2 meeting with the FDA Company plans to submit Investigational New Drug (IND) applica

October 17, 2024 SC 13G/A

ALT / Altimmune, Inc. / STATE STREET CORP Passive Investment

SC 13G/A 1 AltimmuneInc.htm SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* ALTIMMUNE INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 02155H200 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule pursuant to which

October 16, 2024 SC 13G/A

ALT / Altimmune, Inc. / MILLENNIUM MANAGEMENT LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (AMENDMENT NO. 1) ALTIMMUNE, INC. (Name of Issuer) COMMON STOCK, PAR VALUE $0.0001 PER SHARE (Title of Class of Securities) 02155H200 (CUSIP Number) SEPTEMBER 30, 2024 (Date of event which requires filing of this statement) Check the appropriate box to designate the rule p

September 26, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 26, 2024 ALTIMMUNE, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 26, 2024 ALTIMMUNE, INC.

August 15, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 13, 2024 ALTIMMUNE, INC. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 13, 2024 ALTIMMUNE, INC.

August 15, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.  )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 1

August 8, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2024 ALTIMMUNE, INC. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2024 ALTIMMUNE, INC.

August 8, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001

August 8, 2024 EX-99.1

Altimmune Announces Second Quarter 2024 Financial Results and Provides a Business Update Recent presentations at major medical meetings provide further support for the differentiated profile of pemvidutide in obesity and metabolic dysfunction-associa

Exhibit 99.1 Altimmune Announces Second Quarter 2024 Financial Results and Provides a Business Update Recent presentations at major medical meetings provide further support for the differentiated profile of pemvidutide in obesity and metabolic dysfunction-associated steatohepatitis (MASH) Enrollment progressing in Phase 2b IMPACT trial of pemvidutide in MASH with topline data expected in Q1 2025 C

June 26, 2024 EX-99.1

Altimmune Mourns Passing of Chief Financial Officer, Richard Eisenstadt

Exhibit 99.1 Altimmune Mourns Passing of Chief Financial Officer, Richard Eisenstadt GAITHERSBURG, MD – June 26, 2024 – Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced that Richard Eisenstadt, the Company’s Chief Financial Officer, passed away unexpectedly on Monday, June 24, 2024. “We are all shocked and saddened by Rich’s passing. On behalf of everyone

June 26, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 25, 2024 ALTIMMUNE, INC. (Exac

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 25, 2024 ALTIMMUNE, INC.

May 9, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 00

May 9, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 9, 2024 ALTIMMUNE, INC. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 9, 2024 ALTIMMUNE, INC.

May 9, 2024 EX-99.1

Altimmune Announces First Quarter 2024 Financial Results and Provides a Business Update Enrollment ongoing in IMPACT Phase 2b trial of pemvidutide in Metabolic Dysfunction-Associated Steatohepatitis (MASH), with top line results expected in Q1 2025 C

Exhibit 99.1 Altimmune Announces First Quarter 2024 Financial Results and Provides a Business Update Enrollment ongoing in IMPACT Phase 2b trial of pemvidutide in Metabolic Dysfunction-Associated Steatohepatitis (MASH), with top line results expected in Q1 2025 Cash, cash equivalents and short-term investments of $182.1 million at March 31, 2024 Webcast to be held today, May 9, 2024, at 8:30 am ET

March 27, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-32

March 27, 2024 EX-97

Policy Relating to Recovery of Erroneously Awarded Compensation

Exhibit 97 ALTIMMUNE, INC. COMPENSATION RECOVERY POLICY Adopted as of September 28, 2023 Altimmune, Inc., a Delaware corporation (the “Company”), has adopted a Compensation Recovery Policy (this “Policy”) as described below. 1.Overview The Policy sets forth the circumstances and procedures under which the Company shall recover Erroneously Awarded Compensation from Covered Persons (as defined below

March 27, 2024 EX-4.2

Description of Registrant’s Securities

Exhibit 4.2 Description of the Registrant’s Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934, as amended The summary of the general terms and provisions of the registered securities of Altimmune, Inc. (“Altimmune” “we,” or “our”) set forth below does not purport to be complete and is subject to and qualified in its entirety by reference to our Amended and Restate

March 27, 2024 EX-99.1

Altimmune Announces Positive Lean Mass Preservation Data for Pemvidutide and Reports Fourth Quarter and Full Year 2023 Financial Results Body composition study showed lean mass preservation, with only 25.5% of weight loss derived from lean mass Enrol

Exhibit 99.1 Altimmune Announces Positive Lean Mass Preservation Data for Pemvidutide and Reports Fourth Quarter and Full Year 2023 Financial Results Body composition study showed lean mass preservation, with only 25.5% of weight loss derived from lean mass Enrollment ongoing in IMPACT Phase 2b trial of pemvidutide in Metabolic Dysfunction-Associated Steatohepatitis (MASH), with topline 24-week da

March 27, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 27, 2024 ALTIMMUNE, INC. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 27, 2024 ALTIMMUNE, INC.

March 27, 2024 EX-21

SIGNIFICANT SUBSIDIARIES

Exhibit 21 SIGNIFICANT SUBSIDIARIES List of Subsidiaries Jurisdiction of Incorporation or Organization Altimmune, LLC (1) Delaware Altimmune UK, Limited (1) United Kingdom Spitfire Pharma, LLC (1) Delaware Altimmune AU Pty, Limited (1) Australia (1) Wholly owned subsidiary of the Company

March 27, 2024 S-8

As filed with the Securities and Exchange Commission on March 27, 2024

As filed with the Securities and Exchange Commission on March 27, 2024 Registration No.

March 27, 2024 EX-FILING FEES

Filing Fee Table

EXHIBIT 107.1 Calculation of Filing Fee Table Form S-8 (Form Type) Altimmune, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1 - Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Share(2) Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Common stock, $0.0001 par

March 5, 2024 SC 13G

ALT / Altimmune, Inc. / MILLENNIUM MANAGEMENT LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 ALTIMMUNE, INC. (Name of Issuer) COMMON STOCK, PAR VALUE $0.0001 PER SHARE (Title of Class of Securities) 02155H200 (CUSIP Number) FEBRUARY 26, 2024 (Date of event which requires filing of this statement) Check the appropriate box to designate the rule pursuant to which th

February 14, 2024 SC 13G

ALT / Altimmune, Inc. / AMERIPRISE FINANCIAL INC - SC 13G Passive Investment

SC 13G SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities and Exchange Act of 1934 Altimmune, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: This Sched

February 14, 2024 SC 13G/A

ALT / Altimmune, Inc. / TEACHERS ADVISORS, LLC Passive Investment

CUSIP No. 02155H200 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Altimmune, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this S

February 14, 2024 SC 13G/A

ALT / Altimmune, Inc. / Avidity Partners Management LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

February 14, 2024 EX-99.III

to Schedule 13G Powers of Attorney LIMITED POWER OF ATTORNEY

EX-99.III 4 d774900dex99iii.htm EX-99.III Exhibit III to Schedule 13G Powers of Attorney LIMITED POWER OF ATTORNEY KNOW ALL MEN BY THESE PRESENTS, which are intended to constitute a Limited Power of Attorney, that TAM UK International Holdings Limited, a company incorporated under the laws of England and Wales under registered number 12728685, with its principal place of business at Cannon Place,

February 14, 2024 SC 13G/A

ALT / Altimmune, Inc. / Nuveen Asset Management, LLC Passive Investment

CUSIP No. 02155H200 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Altimmune, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this S

February 14, 2024 SC 13G/A

ALT / Altimmune, Inc. / TIAA CREF INVESTMENT MANAGEMENT LLC Passive Investment

SC 13G/A 1 c108110sc13ga.htm CUSIP No. 02155H200 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Altimmune, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the

February 14, 2024 EX-99.II

to Schedule 13G Joint Filing Agreement

EX-99.II 3 d774900dex99ii.htm EX-99.II Exhibit II to Schedule 13G Joint Filing Agreement The undersigned persons agree and consent to the joint filing on their behalf of this Schedule 13G dated February 14, 2024 in connection with their beneficial ownership of Altimmune, Inc. Each of TAM UK International Holdings Limited, Threadneedle Holdings Limited, TAM UK Holdings Limited, Threadneedle Asset M

February 14, 2024 SC 13G/A

ALT / Altimmune, Inc. / TANG CAPITAL PARTNERS LP - AMENDMENT NO. 2 Passive Investment

Securities and Exchange Commission Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No.

February 14, 2024 EX-99.I

to Schedule 13G

EX-99.I Exhibit I to Schedule 13G Ameriprise Financial, Inc., a Delaware Corporation, is a parent holding company. The classification and identity of the relevant subsidiaries is as follows: Non-US Institution – TAM UK International Holdings Limited, a private limited company incorporated in England and Wales, is a holding company and parent entity to Threadneedle Holdings Limited. Non-US Institut

February 13, 2024 SC 13G/A

ALT / Altimmune, Inc. / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 1)* Name of issuer: Altimmune Inc Title of Class of Securities: Common Stock CUSIP Number: 02155H200 Date of Event Which Requires Filing of this Statement: December 29, 2023 Check the appropriate box to designate the rule pursuant to which this Schedule is filed: ☒ Rule

November 30, 2023 EX-99.1

Altimmune Announces Positive Topline Results from MOMENTUM 48-Week Phase 2 Obesity Trial of Pemvidutide

Exhibit 99.1 Altimmune Announces Positive Topline Results from MOMENTUM 48-Week Phase 2 Obesity Trial of Pemvidutide ● Achieved mean weight loss of 15.6% on 2.4 mg dose of pemvidutide at Week 48, with weight loss continuing at the end of treatment ● Over 30% of subjects achieved 20% or more weight loss on 2.4 mg dose at 48 weeks ● Robust reductions in BMI and serum lipids and improvements in blood

November 30, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 30, 2023 ALTIMMUNE, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 30, 2023 ALTIMMUNE, INC.

November 30, 2023 EX-99.2

MOMENTUM Trial • Phase 2, 48-week trial of pemvidutide, a balanced (1:1) GLP-1/glucagon dual receptor agonist, in 391 subjects with overweight or obesity • Randomized 1:1:1:1 to 1 of 4 treatment arms, stratified by gender and baseline BMI, with stand

Exhibit 99.2 MOMENTUM—Pemvidutide Phase 2 Obesity Trial Topline Week 48 Results NASDAQ: ALT 30 November 2023 Forward-looking statements Safe-Harbor Statement This presentation has been prepared by Altimmune, Inc. ("we," "us," "our," "Altimmune" or the "Company") and includes certain “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, including,

November 7, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numbe

November 7, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 7, 2023 ALTIMMUNE, INC.

November 7, 2023 EX-99.1

Altimmune Announces Third Quarter 2023 Financial Results and Provides a Business Update Top-line 48-week results from the MOMENTUM Phase 2 obesity trial expected Q4 2023 Pemvidutide granted Fast Track designation for the treatment of non-alcoholic st

Exhibit 99.1 Altimmune Announces Third Quarter 2023 Financial Results and Provides a Business Update Top-line 48-week results from the MOMENTUM Phase 2 obesity trial expected Q4 2023 Pemvidutide granted Fast Track designation for the treatment of non-alcoholic steatohepatitis (NASH) Top-line results from the Phase 2 trial of HepTcellTM in chronic hepatitis B (CHB) expected Q1 2024 Webcast to be he

September 28, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 28, 2023 ALTIMMUNE, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 28, 2023 ALTIMMUNE, INC.

August 16, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.  )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 1

August 10, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001

August 10, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 10, 2023 ALTIMMUNE, INC. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 10, 2023 ALTIMMUNE, INC.

August 10, 2023 EX-99.1

Altimmune Announces Second Quarter 2023 Financial Results and Provides a Business Update Top-line 48-week results from the MOMENTUM Phase 2 obesity trial expected Q4 2023 Commenced enrollment in IMPACT Phase 2b trial of pemvidutide in non-alcoholic s

Exhibit 99.1 Altimmune Announces Second Quarter 2023 Financial Results and Provides a Business Update Top-line 48-week results from the MOMENTUM Phase 2 obesity trial expected Q4 2023 Commenced enrollment in IMPACT Phase 2b trial of pemvidutide in non-alcoholic steatohepatitis (NASH) Top-line results from the Phase 2 trial of HepTcellTM in chronic hepatitis B (CHB) expected Q1 2024 Webcast to be h

May 11, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2023 ALTIMMUNE, INC. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2023 ALTIMMUNE, INC.

May 11, 2023 EX-99.1

Altimmune Announces First Quarter 2023 Financial Results and Provides a Business Update Initiation of the IMPACT Phase 2b trial of pemvidutide in non-alcoholic steatohepatitis (NASH) expected mid-2023 Top-line 48-week results from the MOMENTUM Phase

Exhibit 99.1 Altimmune Announces First Quarter 2023 Financial Results and Provides a Business Update Initiation of the IMPACT Phase 2b trial of pemvidutide in non-alcoholic steatohepatitis (NASH) expected mid-2023 Top-line 48-week results from the MOMENTUM Phase 2 obesity trial expected Q4 2023 Top-line results from the Phase 2 trial of HepTcellTM in chronic hepatitis B (CHB) expected Q1 2024 Webc

May 11, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 00

April 12, 2023 SC 13G/A

ALT / Altimmune Inc / TIAA CREF INVESTMENT MANAGEMENT LLC Passive Investment

CUSIP No. 02155H200 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. 2)* ALTIMMUNE INC. (Name of Issuer) Common Stock (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to

March 27, 2023 EX-99.1

Altimmune Appoints Former GSK Executive Catherine Angell Sohn, Pharm.D. to its Board of Directors

Exhibit 99.1 Altimmune Appoints Former GSK Executive Catherine Angell Sohn, Pharm.D. to its Board of Directors GAITHERSBURG, Maryland, March 27, 2023 - Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced the appointment of Catherine Angell Sohn, Pharm.D. to its Board of Directors. “We are delighted to welcome Catherine to our Board of Directors”, said Vipin K

March 27, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 23, 2023 ALTIMMUNE, INC. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 23, 2023 ALTIMMUNE, INC.

March 21, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 21, 2023 ALTIMMUNE, INC. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 21, 2023 ALTIMMUNE, INC.

March 21, 2023 EX-99.2

MOMENTUM Trial Design • Phase 2, 48-week trial of pemvidutide in approx 320 subjects with overweight or obesity • Randomized 1:1:1:1 to 1 of 4 treatment arms, stratified by sex and baseline BMI, with standard lifestyle interventions • No or rapid (4

Exhibit 99.2 MOMENTUM—Pemvidutide Phase 2 Obesity Trial Week 24 Interim Analysis NASDAQ: ALT M. Scott Harris, MD, Chief Medical Officer Louis Aronne, MD, Principal Investigator Sanford I. Weill Professor of Metabolic Research Professor of Clinical Medicine, Weill Cornell Medicine 21 March 2023 Forward-looking statements Safe-Harbor Statement This presentation has been prepared by Altimmune, Inc. (

March 21, 2023 EX-99.1

Altimmune Announces Positive Results from Week 24 Interim Analysis of Pemvidutide MOMENTUM Phase 2 Obesity Trial and 12-Week Phase 1b Type 2 Diabetes Safety Trial

Exhibit 99.1 Altimmune Announces Positive Results from Week 24 Interim Analysis of Pemvidutide MOMENTUM Phase 2 Obesity Trial and 12-Week Phase 1b Type 2 Diabetes Safety Trial MOMENTUM Phase 2 Obesity Trial (Week 24 Interim Analysis of 160 Subjects) ● Mean weight loss of 10.7% (placebo-adjusted 9.7%) at 2.4 mg dose at Week 24 ● Mean weight loss of 11.9% (placebo-adjusted 11.1%) in subjects weighin

February 28, 2023 EX-4.4

Form of Senior Indenture between Registrant and one or more trustees to be named

Exhibit 4.4 Altimmune Inc. Issuer AND [TRUSTEE], Trustee INDENTURE Dated as of [ ], 2023 Senior Debt Securities TABLE OF CONTENTS! ARTICLE 1 DEFINITIONS Section 1.01 Definitions of Terms ARTICLE 2 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.0I Designation and Terms of Securities 4 Section 2.02 Form of Securities and Trustee's Certificate 6 Section 2.03

February 28, 2023 EX-4.5

Form of Subordinated Indenture between Registrant and one or more trustees to be named

Exhibit 4.5 ALTIMMUNE INC., Issuer AND [TRUSTEE], Trustee INDENTURE Dated as of [ ], 2023 Subordinated Debt Securities TABLE OF CONTENTS! ARTICLE 1 DEFINITIONS Section 1.01 Definitions of Terms ARTICLE 2 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.01 Designation and Terms of Securities 4 Section 2.02 Form of Securities and Trustee's Certificate 6 Secti

February 28, 2023 EX-10.30

Employment Agreement, dated January 1, 2023, by and between Altimmune, Inc. and Raymond M. Jordt (incorporated by reference to Exhibit 10.30 to the Registrant’s Form 10-K filed on February 28, 2023)

Exhibit 10.30 EMPLOYMENT AGREEMENT This EMPLOYMENT AGREEMENT (“Agreement”) is made and entered into as of January 1, 2023, by and between Raymond Jordt (“Jordt”) and Altimmune, Inc., a Delaware corporation (“Altimmune” or the “Company”). WHEREAS, the Board of Directors of Altimmune (the “Board”) desires to employ Jordt, and Jordt desires to be employed by Altimmune pursuant to the terms and condit

February 28, 2023 EX-4.10

Description of Registrant’s Securities

Exhibit 4.10 Description of the Registrant’s Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934, as amended The summary of the general terms and provisions of the registered securities of Altimmune, Inc. (“Altimmune” “we,” or “our”) set forth below does not purport to be complete and is subject to and qualified in its entirety by reference to our Amended and Restat

February 28, 2023 EX-99.1

Altimmune Announces Fourth Quarter and Full Year 2022 Financial Results and Provides a Business Update Interim 24-week readout from MOMENTUM Phase 2 obesity trial expected March 2023 Initiation of Phase 2b non-alcoholic steatohepatitis (NASH) trial e

Exhibit 99.1 Altimmune Announces Fourth Quarter and Full Year 2022 Financial Results and Provides a Business Update Interim 24-week readout from MOMENTUM Phase 2 obesity trial expected March 2023 Initiation of Phase 2b non-alcoholic steatohepatitis (NASH) trial expected mid-2023 Webcast to be held today, February 28, 2023, at 8:30 am ET GAITHERSBURG, Maryland - February 28, 2023 - Altimmune, Inc.

February 28, 2023 S-3ASR

As filed with the Securities and Exchange Commission on February 28, 2023

Table of Contents As filed with the Securities and Exchange Commission on February 28, 2023 Registration No.

February 28, 2023 S-8

As filed with the Securities and Exchange Commission on February 28, 2023

As filed with the Securities and Exchange Commission on February 28, 2023 Registration No.

February 28, 2023 EX-21

SIGNIFICANT SUBSIDIARIES

Exhibit 21 SIGNIFICANT SUBSIDIARIES List of Subsidiaries Jurisdiction of Incorporation or Organization Altimmune, LLC (1) Delaware Altimmune UK, Limited (1) United Kingdom Spitfire Pharma, LLC (1) Delaware Altimmune AU Pty, Limited (1) Australia (1) Wholly owned subsidiary of the Company

February 28, 2023 EX-FILING FEES

Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Altimmune, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate (5) Amount of Registration Fee (5)

February 28, 2023 EX-FILING FEES

Filing Fee Table

EXHIBIT 107.1 Calculation of Filing Fee Table Form S-8 (Form Type) Altimmune, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1 - Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Share(2) Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Common stock, $0.0001 par

February 28, 2023 EX-10.7

Altimmune, Inc. Non-Employee Director Compensation Policy

Exhibit 10.7 ALTIMMUNE, INC. NON-EMPLOYEE DIRECTOR COMPENSATION POLICY The purpose of this Director Compensation Policy of Altimmune, Inc. (the “Company”), is to provide a total compensation package that enables the Company to attract and retain, on a long-term basis, high-caliber directors who are not employees or officers of the Company or its subsidiaries. In furtherance of the purpose stated a

February 28, 2023 EX-1.2

Equity Distribution Agreement, dated as of February 28, 2023 among the Registrant and Evercore Group L.L.C., JMP Securities LLC and B. Riley Securities, Inc. (incorporated by reference to Exhibit 1.2 to the Registrant’s Form S-3ASR filed on February 28, 2023)

Exhibit 1.2 ALTIMMUNE, INC. EQUITY DISTRIBUTION AGREEMENT February 28, 2023 EVERCORE GROUP L.L.C. 55 East 52nd Street New York, New York 10055 JMP SECURITIES LLC 600 Montgomery Street, Suite 1100 San Francisco, California 94111 B. RILEY SECURITIES, INC. 299 Park Avenue, 21st Floor New York, New York 10171 Ladies and Gentlemen: As further set forth in this agreement (this “Agreement”), Altimmune, I

February 28, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 28, 2023 ALTIMMUNE, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 28, 2023 ALTIMMUNE, INC.

February 28, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-32

February 14, 2023 SC 13G/A

ALT / Altimmune Inc / Avidity Partners Management LP Passive Investment

SC 13G/A 1 d912790213g-a.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Altimmune Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate b

February 14, 2023 SC 13G/A

ALT / Altimmune Inc / TIAA CREF INVESTMENT MANAGEMENT LLC Passive Investment

SC 13G/A 1 c105522sc13ga.htm CUSIP No. 02155H200 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. 1)* ALTIMMUNE INC. (Name of Issuer) Common Stock (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to d

February 14, 2023 SC 13G/A

ALT / Altimmune Inc / Cormorant Asset Management, LP Passive Investment

SC 13G/A 1 schedule13g.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Altimmune, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2022 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pur

February 14, 2023 SC 13G/A

ALT / Altimmune Inc / TANG CAPITAL PARTNERS LP - AMENDMENT NO. 1 Passive Investment

SC 13G/A 1 alt28230sc13ga1.htm AMENDMENT NO. 1 Securities and Exchange Commission Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Altimmune, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of This Statement) Check the approp

February 9, 2023 SC 13G

ALT / Altimmune Inc / VANGUARD GROUP INC - SCHEDULE 13G Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 Name of issuer: Altimmune Inc. Title of Class of Securities: Common Stock CUSIP Number: 02155H200 Date of Event Which Requires Filing of this Statement: December 30, 2022 Check the appropriate box to designate the rule pursuant to which this Schedule is filed: ☒ Rule 13d-1(b) ☐ Rule 13d

December 20, 2022 EX-99.1

Altimmune Announces Positive Topline Results from 24-Week (12-Week Extension) Trial of Pemvidutide in Subjects with Non-Alcoholic Fatty Liver Disease (NAFLD)

Exhibit 99.1 Altimmune Announces Positive Topline Results from 24-Week (12-Week Extension) Trial of Pemvidutide in Subjects with Non-Alcoholic Fatty Liver Disease (NAFLD) ? ? Greater than 75% relative reduction in liver fat content achieved at the 1.8 mg and 2.4 mg doses at 24 weeks ? Significant reductions in serum alanine aminotransferase (ALT) and corrected T1 (cT1) observed, both established m

December 20, 2022 EX-99.2

Pemvidutide NAFLD Extension Trial Design • 83 subjects who completed the 12 - week Phase 1b NAFLD trial were invited to participate, to receive a total of 24 weeks of treatment • 12 - week extension trial of pemvidutide in subjects with non - alcohol

Exhibit 99.2 A 24 - Week (12 - Week Extension) Trial of Pemvidutide in Subjects with Non - alcoholic Fatty Liver Disease (NAFLD) NASDAQ: ALT Stephen Harrison, MD, Lead Investigator 20 December 2022 Forward - looking statements Safe - Harbor Statement This presentation has been prepared by Altimmune, Inc .. ("we," "us," "our," "Altimmune" or the "Company") and includes certain ?forward - looking st

December 20, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 20, 2022 ALTIMMUNE, INC.

November 10, 2022 EX-99.1

Altimmune Announces Third Quarter 2022 Financial Results and Provides a Business Update Topline 24-week data from Phase 1b trial in subjects with non-alcoholic fatty liver disease (NAFLD) expected mid-December 2022 Interim 24-week readout from MOMENT

Exhibit 99.1 Altimmune Announces Third Quarter 2022 Financial Results and Provides a Business Update Topline 24-week data from Phase 1b trial in subjects with non-alcoholic fatty liver disease (NAFLD) expected mid-December 2022 Interim 24-week readout from MOMENTUM Phase 2 obesity trial expected Q1 2023 GAITHERSBURG, Maryland - November 10, 2022 - Altimmune, Inc. (Nasdaq: ALT), a clinical-stage bi

November 10, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2022 ALTIMMUNE, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2022 ALTIMMUNE, INC.

November 10, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

September 29, 2022 8-K

Submission of Matters to a Vote of Security Holders

? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 29, 2022 ALTIMMUNE, INC.

September 14, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 14, 2022 ALTIMMUNE, INC.

September 14, 2022 EX-99.2

Forward - looking statements Safe - Harbor Statement This presentation has been prepared by Altimmune , Inc . ("we," "us," "our," " Altimmune " or the "Company") and includes certain “forward - looking statements” within the meaning of the Private Se

Exhibit 99.2 12 - Week, Phase 1b Study of Pemvidutide in Overweight and Obese Subjects with Non - Alcoholic Fatty Liver Disease (NAFLD) ? Topline Results NASDAQ: ALT Stephen Harrison, MD, Lead Investigator 14 September 2022 Forward - looking statements Safe - Harbor Statement This presentation has been prepared by Altimmune , Inc .. ("we," "us," "our," " Altimmune " or the "Company") and includes

September 14, 2022 EX-99.1

Altimmune Announces Significant Reductions in Liver Fat Content and Body Weight in 12-Week Phase 1b Clinical Trial of Pemvidutide in Subjects with NAFLD

Exhibit 99.1 Altimmune Announces Significant Reductions in Liver Fat Content and Body Weight in 12-Week Phase 1b Clinical Trial of Pemvidutide in Subjects with NAFLD ? ? All 3 pemvidutide dosing groups (1.2 mg, 1.8 mg, 2.4 mg) achieved the primary endpoint of relative and absolute reductions in liver fat, with a 68.5% relative reduction in liver fat content in subjects receiving 1.8 mg dose at 12

August 16, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.  )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 1

August 11, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 11, 2022 ALTIMMUNE, INC.

August 11, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

August 11, 2022 EX-99.1

Altimmune Announces Second Quarter 2022 Financial Results and Provides a Business Update Topline data from 12-week Phase 1b trial in subjects with obesity/overweight and non-alcoholic fatty liver disease (NAFLD) expected mid-September 2022

Exhibit 99.1 Altimmune Announces Second Quarter 2022 Financial Results and Provides a Business Update ? Topline data from 12-week Phase 1b trial in subjects with obesity/overweight and non-alcoholic fatty liver disease (NAFLD) expected mid-September 2022 ? ? GAITHERSBURG, MD, - August 11, 2022 - Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced financial re

July 7, 2022 EX-99.1

JOINT FILING AGREEMENT

Exhibit 99.1 JOINT FILING AGREEMENT This Joint Filing Agreement, dated as of July 7, 2022, is by and among Cormorant Global Healthcare Master Fund, LP, Cormorant Global Healthcare GP, LLC, Cormorant Asset Management, LP and Bihua Chen (collectively, the ?Filers?). Each of the Filers may be required to file with the United States Securities and Exchange Commission a statement on Schedule 13D and/or

July 7, 2022 SC 13G

ALT / Altimmune Inc / Cormorant Asset Management, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Altimmune, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 02155H200 (CUSIP Number) June 27, 2022 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is

May 12, 2022 EX-99.1

Altimmune Announces First Quarter 2022 Financial Results and Provides a Corporate Update Multiple clinical trial data readouts expected in Q3 and Q4 2022

Exhibit 99.1 Altimmune Announces First Quarter 2022 Financial Results and Provides a Corporate Update ? Multiple clinical trial data readouts expected in Q3 and Q4 2022 ? ? GAITHERSBURG, MD, - May 12, 2022 - Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced financial results for the three months ended March 31, 2022 and provided a corporate update. ? ?We co

May 12, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

May 12, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 12, 2022 ALTIMMUNE, INC.

March 24, 2022 SC 13G

ALT / Altimmune Inc / TANG CAPITAL PARTNERS LP Passive Investment

Securities and Exchange Commission Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

March 24, 2022 EX-99.1

JOINT FILING AGREEMENT

Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1) promulgated under the Securities Exchange Act of 1934, the undersigned agree to the joint filing of a Statement on Schedule 13G (including any and all amendments thereto) with respect to the Common Stock, $0.0001 par value per share, of Altimmune, Inc. and further agree to the filing of this Joint Filing Agreement as an exhibi

March 15, 2022 S-8

As filed with the Securities and Exchange Commission on March 15, 2022

As filed with the Securities and Exchange Commission on March 15, 2022 Registration No.

March 15, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 ? FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to ? Commission File Number: 001-32587 ALTIMM

March 15, 2022 EX-99.1

Altimmune Reports Fourth Quarter and Full Year 2021 Financial Results and Provides a Corporate Update Data readouts from multiple clinical trials expected during the next 6 to 12 months Strong cash position of $190.3 million as of December 31, 2021

Exhibit 99.1 Altimmune Reports Fourth Quarter and Full Year 2021 Financial Results and Provides a Corporate Update ? Data readouts from multiple clinical trials expected during the next 6 to 12 months ? Strong cash position of $190.3 million as of December 31, 2021 ? ? GAITHERSBURG, MD, - March 15, 2022 - Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced fi

March 15, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 15, 2022 ALTIMMUNE, INC.

March 15, 2022 EX-4.10

Description of Registrant’s Securities

Exhibit 4.10 ? Description of the Registrant?s Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934, as amended ? The summary of the general terms and provisions of the registered securities of Altimmune, Inc. (?Altimmune? ?we,? or ?our?) set forth below does not purport to be complete and is subject to and qualified in its entirety by reference to our Amended and Re

March 15, 2022 EX-21

SIGNIFICANT SUBSIDIARIES

Exhibit 21 SIGNIFICANT SUBSIDIARIES ? List of Subsidiaries ? Jurisdiction of Incorporation or Organization Altimmune, LLC (1) ? Delaware Altimmune UK, Limited (1) ? United Kingdom Spitfire Pharma, LLC (1) ? Delaware Altimmune AU Pty, Limited (1) ? Australia (1) Wholly owned subsidiary of the Company

March 15, 2022 EX-FILING FEES

Filing Fee Table

EXHIBIT 107.1 Calculation of Filing Fee Table Form S-8 (Form Type) Altimmune, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1 - Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Share(2) Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Common stock, $0.0001 par

February 14, 2022 SC 13G/A

ALT / Altimmune Inc / SPHERA FUNDS MANAGEMENT LTD. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Amendment No. 1)* Altimmune, Inc. (Name of Issuer) Common stock, par value $0.0001 per share (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: ?

February 14, 2022 SC 13G/A

ALT / Altimmune Inc / Venrock Healthcare Capital Partners II, L.P. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G/A UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1)* Altimmune, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule pursuant to which this Sched

February 14, 2022 SC 13G/A

ALT / Altimmune Inc / BAKER BROS. ADVISORS LP - SC 13G/A Passive Investment

SCHEDULE 13G SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 Under the Securities Exchange Act of 1934 (Amendment No.

February 14, 2022 EX-99

Joint Filing Agreement

Exhibit 1 Joint Filing Agreement Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree that only one statement containing the information required by Schedule 13G need be filed with respect to the ownership by each of the undersigned of shares of Altimmune, Inc.

February 11, 2022 SC 13G

PLCE / Children's Place Inc / TIAA CREF INVESTMENT MANAGEMENT LLC Passive Investment

CUSIP No. 168905107 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO.)* ALTIMMUNE INC. (Name of Issuer) Common (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which t

February 11, 2022 SC 13G

PLCE / Children's Place Inc / TEACHERS ADVISORS, LLC Passive Investment

CUSIP No. 168905107 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO.)* ALTIMMUNE INC. (Name of Issuer) Common (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which t

January 3, 2022 SC 13G

ALT / Altimmune Inc / Avidity Partners Management LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

December 17, 2021 8-K

Termination of a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): December 17, 2021 ALTIMMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File

December 13, 2021 EX-10.1

Employment Agreement, dated December 10, 2021, by and between Altimmune, Inc. and Richard Eisenstadt (incorporated by reference to Exhibit 10.1 to the Registrant’s Form 8-K filed on December 13, 2021)

Exhibit 10.1 EMPLOYMENT AGREEMENT This EMPLOYMENT AGREEMENT (?Agreement?) is made and entered into as of December 10, 2021, by and between Richard I. Eisenstadt (?Eisenstadt?) and Altimmune, Inc., a Delaware corporation (?Altimmune?). WHEREAS, the Board of Directors of Altimmune (the ?Board?) desires to employ Eisenstadt, and Eisenstadt desires to be employed by Altimmune pursuant to the terms and

December 13, 2021 EX-99.1

Altimmune Appoints Richard Eisenstadt as Chief Financial Officer

Exhibit 99.1 Altimmune Appoints Richard Eisenstadt as Chief Financial Officer GAITHERSBURG, MD, - December 13, 2021 - Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company focused on developing treatments for obesity and liver diseases, today announced the appointment of Richard Eisenstadt as Chief Financial Officer, effective December 31, 2021. Mr. Eisenstadt succeeds Will Bro

December 13, 2021 8-K

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): December 9, 2021 ALTIMMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File N

November 9, 2021 EX-10.1

Amendment No. 8 to Contract Award issued by the Biomedical Advanced Research and Development Authority of the United States Department of Health and Human Services, dated September 17, 2021 (incorporated by reference to Exhibit 10.1 to the Registrant’s Form 10-Q filed on November 9, 2021)

Exhibit 10.1 CERTAIN INFORMATION IDENTIFIED BY BRACKETED ASTERISKS ([* * *]) HAS BEEN OMITTED FROM THIS EXHIBIT BECAUSE IT IS BOTH NOT MATERIAL AND WOULD BE COMPETITIVELY HARMFUL IF PUBLICLY DISCLOSED. AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT PAGE OF PAGES 14 2. AMENDMENT/MODIFICATION NO.5. PROJECT NO. (If applicable) P00008 6. ISSUED BY CODE 7. ADMINISTERED BY (If other than Item 6) COD

November 9, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 9, 2021 ALTIMMUNE, INC.

November 9, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

November 9, 2021 EX-99.1

Altimmune Announces Third Quarter 2021 Financial Results and Provides a Corporate Update Exploratory MRI-PDFF analysis of subjects with hepatic steatosis in recently completed Phase 1 study of pemvidutide shows reduction of liver fat to undetectable

Exhibit 99.1 Altimmune Announces Third Quarter 2021 Financial Results and Provides a Corporate Update ? Exploratory MRI-PDFF analysis of subjects with hepatic steatosis in recently completed Phase 1 study of pemvidutide shows reduction of liver fat to undetectable levels after 6 weeks of treatment ? Approximately $200 Million in cash and short-term investments to advance pipeline ? ? GAITHERSBURG,

September 28, 2021 EX-99.1

Altimmune Announces Positive Results From 12-week Phase 1 Clinical Trial of ALT-801 (Pemvidutide) in Overweight and Obese Volunteers

Exhibit 99.1 Altimmune Announces Positive Results From 12-week Phase 1 Clinical Trial of ALT-801 (Pemvidutide) in Overweight and Obese Volunteers ? Mean weight loss of 10.3% achieved in subjects receiving 1.8 mg dose ? Pemvidutide was well-tolerated without the need for dose titration ? No discontinuations due to treatment-emergent adverse events ? NASH IND has cleared FDA review; 12-week NAFLD st

September 28, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 28, 2021 ALTIMMUNE, INC.

September 24, 2021 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 23, 2021 ALTIMMUNE, INC.

August 31, 2021 EX-99

Joint Filing Agreement by and among the Reporting Persons, dated as of August 31, 2021.

Exhibit 1 Joint Filing Agreement Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree that only one statement containing the information required by Schedule 13G need be filed with respect to the ownership by each of the undersigned of shares of Altimmune, Inc.

August 31, 2021 SC 13G

ALT / Altimmune Inc / SPHERA FUNDS MANAGEMENT LTD. - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Amendment No. )* Altimmune, Inc. (Name of Issuer) Common stock, par value $0.0001 per share (Title of Class of Securities) 02155H200 (CUSIP Number) August 26, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: ? Ru

August 16, 2021 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.  )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 1

August 10, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 10, 2021 ALTIMMUNE, INC.

August 10, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

August 10, 2021 EX-99.1

Altimmune Announces Second Quarter 2021 Financial Results and Provides a Corporate Update 12-week Data Readout from ALT-801 Phase 1 Clinical Trial Expected in September Approximately $218 Million in Cash and Short-Term Investments to Advance Obesity

Exhibit 99.1 Altimmune Announces Second Quarter 2021 Financial Results and Provides a Corporate Update ? 12-week Data Readout from ALT-801 Phase 1 Clinical Trial Expected in September ? Approximately $218 Million in Cash and Short-Term Investments to Advance Obesity and Liver Disease Pipeline ? ? GAITHERSBURG, MD, - August 10, 2021 - Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutica

August 10, 2021 EX-10.1

Amendment No. 7 to Contract Award issued by the Biomedical Advanced Research and Development Authority of the United States Department of Health and Human Services, dated June 29, 2021 (incorporated by reference to Exhibit 10.1 to the Registrant’s Form 10-Q filed on August 10, 2021)

? Exhibit 10.1 CERTAIN INFORMATION IDENTIFIED BY BRACKETED ASTERISKS ([* * *]) HAS BEEN OMITTED FROM THIS EXHIBIT BECAUSE IT IS BOTH NOT MATERIAL AND WOULD BE COMPETITIVELY HARMFUL IF PUBLICLY DISCLOSED. AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT PAGE OF PAGES 13 2. AMENDMENT/MODIFICATION NO.5. PROJECT NO. (If applicable) P00007 6. ISSUED BY CODE 7. ADMINISTERED BY (If other than Item 6) C

June 29, 2021 EX-99.1

Altimmune Announces Update on AdCOVIDTM Phase 1 Clinical Trial

Exhibit 99.1 Altimmune Announces Update on AdCOVIDTM Phase 1 Clinical Trial ? AdCOVID was well tolerated but did not stimulate an adequate immune response in healthy volunteers ? Altimmune will discontinue further development of AdCOVID and focus its resources on its ongoing obesity and liver programs ? Altimmune also provides an update on its T-COVIDTM Phase 1/2 Clinical Trial GAITHERSBURG, MD ?

June 29, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 29, 2021 Altimmune, Inc. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File Numb

June 16, 2021 EX-99.1

Altimmune Announces Positive Interim Data from ALT-801 Phase 1 Trial in Overweight and Obese Volunteers

Exhibit 99.1 Altimmune Announces Positive Interim Data from ALT-801 Phase 1 Trial in Overweight and Obese Volunteers ? Weight loss of 5.4% achieved at 6 weeks of treatment with 1.8 mg once weekly dose, surpassing the 2% pre-established treatment target ? Ascending multi-dose regimen well-tolerated without necessity for dose titration ? Trial continuing with 12-week data expected in Q3 2021 ? Compa

June 16, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 16, 2021 Altimmune, Inc. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File Numb

May 17, 2021 EX-99.2

First Quarter 2021 Results Corporate Update & Financial Results May 17, 2021 NASDAQ: ALT

EX-99.2 3 alt-ex992100.htm EX-99.2 First Quarter 2021 Results Corporate Update & Financial Results May 17, 2021 NASDAQ: ALT 2 Forward-looking statements Safe-Harbor Statement This presentation has been prepared by Altimmune, Inc. ("we," "us," "our," "Altimmune" or the "Company") and includes certain “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of

May 17, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-32587 ALTIMMUNE,

May 17, 2021 EX-10.2

Statement of Work, dated March 9, 2021, by and between Altimmune, Inc. and Lonza Houston Inc.

Exhibit 10.2 Confidential Treatment Requested ? Certain Portions of this Exhibit, Marked as [***], Have Been Omitted Pursuant to a Pending Request for Confidential Treatment and Have Been Filed Separately with the Securities and Exchange Commission Statement of Work This Statement of Work SOW A-04 (this "SOW") is effective as of March 8, 2021 (the "Effective Date") and is agreed to by Altimmune In

May 17, 2021 EX-10.1

Amendment No. 6 to Second Restated License Agreement, effective as of January 22, 2021, between Janssen Vaccines & Prevention B.V. (formerly Crucell Holland B.V.) and Altimmune, Inc. (incorporated by reference to Exhibit 10.1 to the Registrant’s Form 10-Q filed on May 17, 2021)

Exhibit 10.1 AMENDMENT NO. 6 TO SECOND RESTATED LICENSE AGREEMENT This Amendment No. 6 (?Amendment No. 6?) to the Second Restated License Agreement is made and entered into on the date of the last signature below by and between: Janssen Vaccines & Prevention B.V., a company under Dutch law with limited liability, with registered address at Archimedesweg 4, 2333 CN Leiden, The Netherlands (?Janssen

May 17, 2021 EX-99.1

Altimmune Announces First Quarter 2021 Financial Results and Provides a Corporate Update Data Readouts from Phase 1 AdCOVID™ and ALT-801 Clinical Trials Expected in June Approximately $227 Million in Cash and Short-Term Investments to Advance Pipelin

Exhibit 99.1 Altimmune Announces First Quarter 2021 Financial Results and Provides a Corporate Update Data Readouts from Phase 1 AdCOVID? and ALT-801 Clinical Trials Expected in June Approximately $227 Million in Cash and Short-Term Investments to Advance Pipeline GAITHERSBURG, MD, - May 17, 2021 - Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced financial

May 17, 2021 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 17, 2021 ALTIMMUNE, INC. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 17, 2021 ALTIMMUNE, INC.

April 1, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): April 1, 2021 Altimmune, Inc. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File Numb

April 1, 2021 EX-99.1

Altimmune Reports Data from its Phase 1b Clinical Trial of NasoShield™

EX-99.1 Exhibit 99.1 Altimmune Reports Data from its Phase 1b Clinical Trial of NasoShield™ GAITHERSBURG, MD, April 1, 2021 — Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, reported clinical data today on its NasoShield intranasal anthrax vaccine candidate. The Phase 1b trial evaluated the safety and immunogenicity of one and two-dose regimens of NasoShield in healthy v

March 12, 2021 EX-99.1

Altimmune Expands AdCOVID™ Manufacturing Collaboration with Lonza Lonza to Commission a Dedicated Suite for Clinical and Commercial Supply of Altimmune’s COVID-19 Vaccine Candidate at its Houston Facility

EX-99.1 Exhibit 99.1 Altimmune Expands AdCOVID™ Manufacturing Collaboration with Lonza Lonza to Commission a Dedicated Suite for Clinical and Commercial Supply of Altimmune’s COVID-19 Vaccine Candidate at its Houston Facility GAITHERSBURG, Maryland (USA) and Basel, Switzerland, March 12, 2021 — Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced that it has e

March 12, 2021 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): March 9, 2021 Altimmune, Inc. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File Numb

March 1, 2021 SC 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. )* Altimmune, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) (CUSIP Number) February 25,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. )* Altimmune, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 02155H200 (CUSIP Number) February 25, 2021 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule pursuant to which this Schedule

February 25, 2021 EX-10.15

Amendment No. 5 to Second Restated License Agreement, effective as of October 22, 2020, between Janssen Vaccines & Prevention B.V. (formerly Crucell Holland B.V.) and Altimmune, Inc. (incorporated by reference to Exhibit 10.15 to the Registrant’s Form 10-K filed on February 25, 2021)

Exhibit 10.15 AMENDMENT NO. 5 TO SECOND RESTATED LICENSE AGREEMENT This Amendment No. 5 (?Amendment No. 5?) to the Second Restated License Agreement is made and entered into on the date of the last signature below by and between: Janssen Vaccines & Prevention B.V., a company under Dutch law with limited liability, with registered address at Archimedesweg 4, 2333 CN Leiden, The Netherlands (?Jansse

February 25, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 25, 2021 Altimmune, Inc. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File

February 25, 2021 EX-21

SIGNIFICANT SUBSIDIARIES

Exhibit 21 SIGNIFICANT SUBSIDIARIES List of Subsidiaries Jurisdiction of Incorporation or Organization Altimmune, LLC (1) Delaware Altimmune UK, Limited (1) United Kingdom Spitfire Pharma, LLC (1) Delaware Altimmune AU Pty, Limited (1) Australia (1) Wholly owned subsidiary of the Company

February 25, 2021 EX-4.10

Description of Registrant’s Securities

Exhibit 4.10 Description of the Registrant?s Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934, as amended The summary of the general terms and provisions of the registered securities of Altimmune, Inc. (?Altimmune? ?we,? or ?our?) set forth below does not purport to be complete and is subject to and qualified in its entirety by reference to our Amended and Restat

February 25, 2021 EX-99.1

Altimmune Announces Financial Results for the Year Ended December 31, 2020 and Provides a Corporate Update Enrollment in the Phase 1 AdCOVID™ Clinical Trial has Commenced Development of AdCOVID Vectors Targeting Emerging Variants of the SARS-CoV-2 Vi

Exhibit 99.1 Altimmune Announces Financial Results for the Year Ended December 31, 2020 and Provides a Corporate Update Enrollment in the Phase 1 AdCOVID™ Clinical Trial has Commenced Development of AdCOVID Vectors Targeting Emerging Variants of the SARS-CoV-2 Virus has Begun ALT-801 is Progressing Through the Phase 1 Clinical Trial Solidly Capitalized to Advance Pipeline Candidates with $216 Mill

February 25, 2021 EX-99.2

Altimmune Commences Enrollment in Phase 1 Clinical Trial of AdCOVID™ -- a Needle-Free, Single-Dose Intranasal COVID-19 Vaccine Candidate Nasal spray may offer room temperature distribution that could reduce logistical challenges for healthcare system

Exhibit 99.2 Altimmune Commences Enrollment in Phase 1 Clinical Trial of AdCOVID? - a Needle-Free, Single-Dose Intranasal COVID-19 Vaccine Candidate Nasal spray may offer room temperature distribution that could reduce logistical challenges for healthcare systems and providers Intranasal administration targets the virus at its point of entry and in a preclinical study induced local nasal mucosal i

February 25, 2021 EX-1.1

Equity Distribution Agreement, dated February 25, 2021, by and among Altimmune, Inc. and Piper Sandler & Co., Evercore Group L.L.C. and B. Riley Securities, Inc. (incorporated by reference to Exhibit 1.1 to the Registrant’s Form 8-K filed on February 25, 2021)

Exhibit 1.1 ALTIMMUNE, INC. EQUITY DISTRIBUTION AGREEMENT February 25, 2021 PIPER SANDLER & CO. U.S. Bancorp Center 800 Nicollet Mall Minneapolis, Minnesota 55402 EVERCORE GROUP L.L.C. 55 East 52nd Street New York, New York 10055 B. RILEY SECURITIES, INC. 299 Park Avenue, 21st Floor New York, New York 10171 Ladies and Gentlemen: As further set forth in this agreement (this ?Agreement?), Altimmune,

February 25, 2021 EX-10.22

Amendment No. 6 to Contract Award issued by the Biomedical Advanced Research and Development Authority of the United States Department of Health and Human Services, dated December 23, 2020 (incorporated by reference to Exhibit 10.22 to the Registrant’s Form 10-K filed on February 25, 2021)

Exhibit 10.22 CERTAIN INFORMATION IDENTIFIED BY BRACKETED ASTERISKS ([* * *]) HAS BEEN OMITTED FROM THIS EXHIBIT BECAUSE IT IS BOTH NOT MATERIAL AND WOULD BE COMPETITIVELY HARMFUL IF PUBLICLY DISCLOSED. AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT 1. CONTRACT ID CODE PAGE OF PAGES 1 6 2. AMENDMENT/MODIFICATION NO. 3. EFFECTIVE DATE 4. REQUISITION/PURCHASE REQ. NO. 5. PROJECT NO. (If applicab

February 25, 2021 424B5

The date of this prospectus supplement is February 25, 2021.

424B5 1 d24591d424b5.htm 424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-251858 PROSPECTUS SUPPLEMENT (to Prospectus dated January 11, 2021) Up to $125,000,000 Common Stock We have entered into an equity distribution agreement, dated February 25, 2021, or the Equity Distribution Agreement, with Piper Sandler & Co., Evercore Group L.L.C., and B. Riley Securities, Inc.,

February 25, 2021 EX-10.1

Exchange Agreement between Altimmune, Inc. and Venrock Healthcare Capital Partners II, L.P., Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings II, LLC and VHCP Co-Investment Holdings III, LLC, dated February 25, 2021

Exhibit 10.1 February 25, 2021 Altimmune, Inc. 910 Clopper Road, Suite 201S Gaithersburg, Maryland 20878 Re: 3(a)(9) Exchange Agreement Ladies and Gentlemen: This letter agreement (the ?Agreement?) confirms the agreement of Altimmune, Inc., a Delaware corporation (the ?Company?), and the holders of the Common Stock listed on Schedule I attached hereto (the ?Stockholders?), pursuant to which the St

February 25, 2021 EX-4.1

Form of Pre-Funded Warrant

EX-4.1 2 alt-ex417.htm EX-4.1 Exhibit 4.1 FORM OF PRE-FUNDED WARRANT TO PURCHASE COMMON STOCK Number of Shares: [ ] (subject to adjustment) Warrant No. [ ]Original Issue Date: February 25, 2021 Altimmune, Inc., a Delaware corporation (the “Company”), hereby certifies that, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, [ ] or its registered assig

February 25, 2021 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 25, 2021 ALTIMMUNE, INC.

February 25, 2021 10-K

Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-32587 ALTIMMUNE, INC

February 16, 2021 EX-99.1

AGREEMENT

EXHIBIT 99.1 AGREEMENT In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree that this Statement on Schedule 13G relating to the Common Stock of Altimmune, Inc. is being filed with the Securities and Exchange Commission on behalf of each of them. February 16, 2021 BAKER BROS. ADVISORS LP By: Baker Bros. Advisors (GP) LLC, its genera

February 16, 2021 SC 13G/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Amendment No. 1) Under the Securities Exchange Act of 1934 Altimmune, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) (CUSIP Number) December

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Amendment No. 1) Under the Securities Exchange Act of 1934 Altimmune, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the following box to designate the rule pursuant to which the Schedu

February 16, 2021 SC 13G

SCHEDULE 13G SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 Under the Securities Exchange Act of 1934 (Amendment No. )* Altimmune, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) (CUSIP Number)

SCHEDULE 13G SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 Under the Securities Exchange Act of 1934 (Amendment No.

February 16, 2021 EX-99.1

POWER OF ATTORNEY FOR CERTAIN REGULATORY FILINGS INCLUDING CERTAIN FILINGS UNDER THE SECURITIES EXCHANGE ACT OF 1934 AND THE INVESTMENT ADVISERS ACT OF 1940

Exhibit 1 POWER OF ATTORNEY FOR CERTAIN REGULATORY FILINGS INCLUDING CERTAIN FILINGS UNDER THE SECURITIES EXCHANGE ACT OF 1934 AND THE INVESTMENT ADVISERS ACT OF 1940 I, David E.

February 16, 2021 EX-99.2

JOINT FILING AGREEMENT

Exhibit 2 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, each of the undersigned Reporting Persons hereby agrees to the joint filing, along with all other such Reporting Persons, on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Common Stock, $0.

February 16, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Altimmune, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule

February 8, 2021 SC 13G/A

Altimmune, Inc.

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 3)* Altimmune, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 02155H200 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to w

January 7, 2021 CORRESP

-

CORRESP 1 filename1.htm Altimmune, Inc. 910 Clopper Road, Suite 201S Gaithersburg, Maryland 20878 January 7, 2021 Via EDGAR Transmission United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Altimmune, Inc.: Registration Statement on Form S-3, filed December 31, 2020 (File No. 333-251858) Ladies and Gentlemen: Pursuant to Rul

December 31, 2020 S-3

- S-3

S-3 Table of Contents As filed with the Securities and Exchange Commission on December 31, 2020 Registration No.

December 31, 2020 EX-4.2

Form of indenture for subordinated debt securities and the related form of subordinated debt security

Table of Contents Exhibit 4.2 ALTIMMUNE, INC. Issuer AND [TRUSTEE], Trustee INDENTURE Dated as of [●], 202[●] Subordinated Debt Securities Table of Contents Table of Contents Page ARTICLE 1 DEFINITIONS 1 Section 1.01 Definitions of Terms. 1 ARTICLE 2 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.01 Designation and Terms of Securities. 4 Section 2.02 Form

December 31, 2020 EX-4.1

Form of indenture for senior debt securities and the related form of senior debt security

EX-4.1 Table of Contents Exhibit 4.1 ALTIMMUNE, INC. Issuer AND [TRUSTEE], Trustee INDENTURE Dated as of [●], 202[●] Senior Debt Securities Table of Contents Table of Contents Page ARTICLE 1 DEFINITIONS 1 Section 1.01 Definitions of Terms. 1 ARTICLE 2 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.01 Designation and Terms of Securities. 4 Section 2.02 For

December 23, 2020 8-K

Financial Statements and Exhibits, Other Events - 8-K

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): December 23, 2020 Altimmune, Inc. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission F

December 23, 2020 EX-99.1

Altimmune Provides an Update on its Investigational New Drug Application for a Phase 1 AdCOVID™ Clinical Trial

EX-99.1 Exhibit 99.1 Altimmune Provides an Update on its Investigational New Drug Application for a Phase 1 AdCOVID™ Clinical Trial GAITHERSBURG, MD, December 23, 2020 — Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced that the U.S. Food and Drug Administration (FDA) has issued a clinical hold on the Company’s Investigational New Drug (IND) application for

November 9, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 9, 2020 ALTIMMUNE, INC.

November 9, 2020 EX-99.1

Altimmune Announces Third Quarter 2020 Financial Results and Provides a Business Update

Exhibit 99.1 Altimmune Announces Third Quarter 2020 Financial Results and Provides a Business Update GAITHERSBURG, MD, November 9, 2020 - Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced financial results for the three and nine months ended September 30, 2020 and provided a business update. “2020 has been a transformational year for Altimmune as our pipeli

November 9, 2020 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2020 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-32587 ALTIMM

November 9, 2020 EX-10.2

Altimmune, Inc. Non-Employee Director Compensation Policy (incorporated by reference to Exhibit 10.2 to the Registrant’s Form 10-Q, filed on November 9, 2020)

Exhibit 10.2 ALTIMMUNE, INC. NON-EMPLOYEE DIRECTOR COMPENSATION POLICY The purpose of this Director Compensation Policy of Altimmune, Inc. (the ?Company?), is to provide a total compensation package that enables the Company to attract and retain, on a long-term basis, high-caliber directors who are not employees or officers of the Company or its subsidiaries. In furtherance of the purpose stated a

November 9, 2020 EX-10.1

Amendment No. 4 to Second Restated License Agreement, effective as of July 28, 2020, between Janssen Vaccines & Prevention B.V. (formerly Crucell Holland B.V.) and Altimmune, Inc. (incorporated by reference to Exhibit 10.1 to the Registrant’s Form 10-Q filed on November 9, 2020)

Exhibit 10.1 AMENDMENT NO. 4 TO SECOND RESTATED LICENSE AGREEMENT This Amendment No. 4 (?Amendment No. 4?) to the Second Restated License Agreement (?License?) is made and entered into on the date of the last signature below by and between: Janssen Vaccines & Prevention B.V., a company under Dutch law with limited liability, with registered address at Archimedesweg 4, 2333 CN Leiden, The Netherlan

October 5, 2020 EX-99.2

JOINT FILING AGREEMENT

Exhibit 2 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, each of the undersigned Reporting Persons hereby agrees to the joint filing, along with all other such Reporting Persons, on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Common Stock, $0.

October 5, 2020 EX-99.1

POWER OF ATTORNEY FOR CERTAIN REGULATORY FILINGS INCLUDING CERTAIN FILINGS UNDER THE SECURITIES EXCHANGE ACT OF 1934 AND THE INVESTMENT ADVISERS ACT OF 1940

Exhibit 1 POWER OF ATTORNEY FOR CERTAIN REGULATORY FILINGS INCLUDING CERTAIN FILINGS UNDER THE SECURITIES EXCHANGE ACT OF 1934 AND THE INVESTMENT ADVISERS ACT OF 1940 I, David E.

October 5, 2020 SC 13G

ALT / Altimmune, Inc. / D. E. SHAW & CO, L.P. - SC 13G Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Altimmune, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 02155H200 (CUSIP Number) September 25, 2020 (Date of Event Which Requires Filing of this Statement) Check the following box to designate the rule pursuant to which the Schedule is filed: ¨ Ru

September 25, 2020 8-K

Submission of Matters to a Vote of Security Holders - 8-K

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 24, 2020 ALTIMMUNE, INC.

September 24, 2020 EX-99.2

JOINT FILING AGREEMENT

Exhibit 2 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, each of the undersigned Reporting Persons hereby agrees to the joint filing, along with all other such Reporting Persons, on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Common Stock, $0.

September 24, 2020 SC 13G

ALT / Altimmune, Inc. / D. E. SHAW & CO, L.P. - SC 13G Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Altimmune, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 02155H200 (CUSIP Number) September 14, 2020 (Date of Event Which Requires Filing of this Statement) Check the following box to designate the rule pursuant to which the Schedule is filed: ¨ Ru

September 24, 2020 EX-99.1

POWER OF ATTORNEY FOR CERTAIN REGULATORY FILINGS INCLUDING CERTAIN FILINGS UNDER THE SECURITIES EXCHANGE ACT OF 1934 AND THE INVESTMENT ADVISERS ACT OF 1940

Exhibit 1 POWER OF ATTORNEY FOR CERTAIN REGULATORY FILINGS INCLUDING CERTAIN FILINGS UNDER THE SECURITIES EXCHANGE ACT OF 1934 AND THE INVESTMENT ADVISERS ACT OF 1940 I, David E.

August 21, 2020 S-8

Form S-8 filed with the Securities and Exchange Commission on August 21, 2020

S-8 As filed with the Securities and Exchange Commission on August 21, 2020 Registration No.

August 21, 2020 DEF 14A

Schedule 14A

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14

August 11, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2020 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-32587 ALTIMMUNE,

August 11, 2020 EX-10.2

Amendment No. 2 to Second Restated License Agreement, effective as of September 20, 2016, between Janssen Vaccines & Prevention B.V. (formerly Crucell Holland B.V.) and Altimmune, Inc. (incorporated by reference to Exhibit 10.2 to the Registrant’s Form 10-Q filed on August 11, 2020)

Exhibit 10.2 AMENDMENT NO. 2 TO SECOND RESTATED LICENSE AGREEMENT This Amendment No. 2 to the Second Restated License Agreement (this “Amendment No. 2”) is made and effective as of September 20, 2016 by and between Crucell Holland B.V., a corporation organized under the laws of the Netherlands, having offices at Archimedesweg 4-6, 2333 CN Leiden, the Netherlands (“CRUCELL”) and Altimmune, Inc., a

August 11, 2020 EX-10.3

Amendment No. 3 to Second Restated License Agreement, effective as of April 2, 2020, between Janssen Vaccines & Prevention B.V. (formerly Crucell Holland B.V.) and Altimmune, Inc. (incorporated by reference to Exhibit 10.3 to the Registrant’s Form 10-Q filed on August 11, 2020)

Exhibit 10.3 CERTAIN INFORMATION IDENTIFIED BY BRACKETED ASTERISKS ([* * *]) HAS BEEN OMITTED FROM THIS EXHIBIT BECAUSE IT IS BOTH NOT MATERIAL AND WOULD BE COMPETITIVELY HARMFUL IF PUBLICLY DISCLOSED. AMENDMENT NO. 3 TO SECOND RESTATED LICENSE AGREEMENT This Amendment No. 3 (“Amendment No. 3”) to the Second Restated License Agreement (“License”) is made and entered into on the date of the last si

August 11, 2020 EX-99.1

Altimmune Announces Second Quarter 2020 Financial Results and Provides a Business Update

Exhibit 99.1 Altimmune Announces Second Quarter 2020 Financial Results and Provides a Business Update GAITHERSBURG, Maryland, August 11, 2020 - Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced financial results for the three and six months ended June 30, 2020 and provided a business update. “We are pleased with Altimmune’s progress during 2020 as we have l

August 11, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 11, 2020 ALTIMMUNE, INC.

July 16, 2020 EX-99.3

Altimmune Announces Closing of $132 Million Public Offering of Common Stock and Pre-Funded Warrants and Full Exercise of Underwriters’ Option

EX-99.3 Exhibit 99.3 Altimmune Announces Closing of $132 Million Public Offering of Common Stock and Pre-Funded Warrants and Full Exercise of Underwriters’ Option GAITHERSBURG, Maryland, July 16, 2020 (GLOBE NEWSWIRE) – Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced that its previously announced underwritten public offering of 4,119,564 shares of its com

July 16, 2020 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 13, 2020 Altimmune, Inc. (Exact Name of Company as Specified in Charter) Delaware 001-32587 20-2726770 (State or Other Jurisdiction of Incorporation) (Commission File Number)

July 16, 2020 EX-99.2

Altimmune Announces Pricing of a Public Offering of $115 Million of Common Stock and Pre-Funded Warrants

EX-99.2 Exhibit 99.2 Altimmune Announces Pricing of a Public Offering of $115 Million of Common Stock and Pre-Funded Warrants GAITHERSBURG, Md., July 13, 2020 (GLOBE NEWSWIRE) – Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced the pricing of its previously announced underwritten public offering of 3,369,564 shares of its common stock and, to certain invest

July 16, 2020 EX-99.1

Altimmune Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants

EX-99.1 Exhibit 99.1 Altimmune Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants GAITHERSBURG, Md., July 13, 2020 (GLOBE NEWSWIRE) – Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced that it intends to offer and sell, subject to market and other conditions, shares of its common stock in an underwritten public offering and, to certai

July 16, 2020 8-K/A

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

8-K/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 11, 2020 Altimmune, Inc. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission Fi

July 16, 2020 EX-4.1

Form of Pre-Funded Warrant

EX-4.1 Exhibit 4.1 FORM OF PRE-FUNDED WARRANT TO PURCHASE COMMON STOCK Number of Shares: [ ] (subject to adjustment) Warrant No. Original Issue Date: July [ ], 2020 Altimmune, Inc., a Delaware corporation (the “Company”), hereby certifies that, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, [ ] or its registered assigns (the “Holder”), is entitle

July 16, 2020 EX-1.1

Underwriting Agreement, dated as of July 13, 2020, among Altimmune, Inc. and Jefferies LLC, Evercore Group L.L.C. and Piper Sandler & Co., as representatives of the underwriters named therein

EX-1.1 Exhibit 1.1 EXECUTION VERSION 3,369,564 Shares of Common Stock and Pre-Funded Warrants to Purchase 1,630,436 shares of Common Stock ALTIMMUNE, INC. UNDERWRITING AGREEMENT July 13, 2020 JEFFERIES LLC EVERCORE GROUP L.L.C. PIPER SANDLER & CO. As Representatives of the several Underwriters c/o JEFFERIES LLC 520 Madison Avenue New York, New York 10022 c/o EVERCORE GROUP L.L.C. 55 East 52nd Stre

July 15, 2020 424B5

3,369,564 Shares of Common Stock Pre-Funded Warrants to Purchase 1,630,436 Shares of Common Stock

424B5 1 d30860d424b5.htm 424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-230723 PROSPECTUS SUPPLEMENT (To prospectus dated April 12, 2019) 3,369,564 Shares of Common Stock Pre-Funded Warrants to Purchase 1,630,436 Shares of Common Stock We are offering an aggregate of 3,369,564 shares of our common stock, par value $0.0001 per share, and, to certain investors in lieu

July 13, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): July 13, 2020 Altimmune, Inc. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File

July 13, 2020 424B5

Shares of Common Stock Pre-Funded Warrants to Purchase Shares of Common Stock

424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-230723 The information in this preliminary prospectus supplement is not complete and may be changed. A registration statement relating to these securities has been filed with the Securities and Exchange Commission and is effective. This preliminary prospectus supplement and the accompanying prospectus are not an offer to

July 13, 2020 EX-99.1

Altimmune and the University of Alabama at Birmingham (UAB) Announce Positive Preclinical Results for Intranasal COVID-19 Vaccine Candidate, AdCOVIDTM AdCOVID stimulated both strong serum neutralizing activity and potent mucosal immunity (IgA) in the

EX-99.1 Exhibit 99.1 Altimmune and the University of Alabama at Birmingham (UAB) Announce Positive Preclinical Results for Intranasal COVID-19 Vaccine Candidate, AdCOVIDTM AdCOVID stimulated both strong serum neutralizing activity and potent mucosal immunity (IgA) in the respiratory tract GAITHERSBURG, MD, July 13, 2020 (GLOBE NEWSWIRE) — Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmace

June 25, 2020 SC 13D

ALT / Altimmune, Inc. / Venrock Healthcare Capital Partners Ii, L.p. - SCHEDULE 13G Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. )* Altimmune, Inc. (Name of Issuer) COMMON STOCK (Title of Class of Securities) 02155H200 (CUSIP Number) Attention: General Counsel Venrock 3340 Hillview Avenue Palo Alto, California 94304 Name, Address and Telephone Number of Person Authorized to Receive No

June 1, 2020 424B5

Common Stock

424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-230723 AMENDMENT NO. 1 DATED June 1, 2020 To Prospectus Supplement dated March 27, 2020 (to Prospectus dated April 12, 2019) $50,000,000 Common Stock This Amendment No. 1 to Prospectus Supplement, or this amendment, amends our prospectus supplement dated March 27, 2020, or the prospectus supplement. This amendment should

June 1, 2020 EX-99.1

Altimmune Launches Clinical Trial of T-COVIDTM, an Investigational Intranasal Immune Modulator for the Treatment of Patients with Early COVID-19

EX-99.1 Exhibit 99.1 Altimmune Launches Clinical Trial of T-COVIDTM, an Investigational Intranasal Immune Modulator for the Treatment of Patients with Early COVID-19 • Clearance of IND application received from the U.S. FDA • Planned Phase 1/2 outpatient clinical trial will focus on patients with early SARS-CoV-2 infection • Placebo-controlled trial expected to commence in June with data readout e

June 1, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): June 1, 2020 Altimmune, Inc. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File N

June 1, 2020 SC 13G

ALT / Altimmune, Inc. / Venrock Healthcare Capital Partners Ii, L.p. - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Altimmune, Inc. (Name of Issuer) COMMON STOCK (Title of Class of Securities) 02155H200 (CUSIP Number) May 20, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is f

May 13, 2020 10-Q

Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2020 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-32587 Altimmune,

May 13, 2020 EX-99.1

Altimmune Announces First Quarter 2020 Financial Results and Provides a Business Update

Exhibit 99.1 Altimmune Announces First Quarter 2020 Financial Results and Provides a Business Update GAITHERSBURG, Maryland, May 13, 2020 - Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced financial results for the quarter ended March 31, 2020 and provided a business update. “Throughout 2020 we have put significant effort into developing our pipeline; from

May 13, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 13, 2020 ALTIMMUNE, INC.

May 12, 2020 EX-99.1

Altimmune Appoints Former Pfizer and GSK Executive Diane Jorkasky, M.D. to its Board of Directors

EX-99.1 Exhibit 99.1 Altimmune Appoints Former Pfizer and GSK Executive Diane Jorkasky, M.D. to its Board of Directors GAITHERSBURG, Maryland, May 12, 2020 — Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced the appointment of Diane Jorkasky, M.D. to its Board of Directors. With Dr. Jorkasky’s appointment, the size of the board increased to eight members. “

May 12, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): May 11, 2020 Altimmune, Inc. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File N

April 8, 2020 8-K

Entry into a Material Definitive Agreement

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 2, 2020 Altimmune, Inc. (Exact name of registrant as specified in its charter) Delaware 001-32587 20-2726770 (State or other jurisdiction of incorporation) (Commission File

Other Listings
GB:0A4C
MX:ALT1
DE:3G0 € ٣٫٠٤
Fintel data has been cited in the following publications:
Daily Mail Fox Business Business Insider Wall Street Journal The Washington Post Bloomberg Financial Times Globe and Mail
NASDAQ.com Reuters The Guardian Associated Press FactCheck.org Snopes Politifact
Federal Register The Intercept Forbes Fortune Magazine TheStreet Time Magazine Canadian Broadcasting Corporation International Business Times
Cambridge University Press Investopedia MarketWatch NY Daily News Entrepreneur Newsweek Barron's El Economista