SGIOF / Shionogi & Co., Ltd. - تصريحات هيئة الأوراق المالية والبورصات، التقرير السنوي، بيان الوكيل

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM F-6 REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts SHIONOGI & CO., LTD. (Exac

Registration No. 333-266935 As filed with the Securities and Exchange Commission October 2, 2024. SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts SHIONOGI & CO., LTD. (Exact name of Issuer of deposited securities as sp

Certification under Rule 466

Exhibit (e) Certification under Rule 466 The depositary, Deutsche Bank Trust Company Americas, represents and certifies the following: (1) That it previously had filed a registration statement on Form F-6 (Hochtief AG, 333-228091), which the U.

Deutsche Bank Trust Company Americas American Depositary Receipt American Depositary Shares Representing Shares of Common Stock of Shionogi & Co., Ltd. (Incorporated under the laws of Japan)

Exhibit (a) SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

AMERICAN DEPOSITARY RECEIPT

Exhibit (a) NUMBER AMERICAN DEPOSITARY SHARES CUSIP # Each American Depositary Share represents one-half (1/2) of one share of common stock of the Company SUBSCRIPTION RIGHTS: Under Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6/A POST-EFFECTIVE AMENDMENT NO. 2 TO REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 FOR DEPOSITARY SHARES EVIDENCED BY AMERICAN DEPOSITARY RECEIPTS SHIONOGI & CO., LTD. (Exact name

As filed with the Securities and Exchange Commission on October 1, 2024 Registration No.

Rule 466 Certification

Exhibit (e) Rule 466 Certification The depositary, Citibank, N.A., represents and certifies the following: 1. That it previously had filed a registration statement on Form F-6 (Registration No. 333-227277), which the U.S. Securities and Exchange Commission declared effective, with terms of deposit identical to the terms of deposit of this Post-Effective Amendment No. 2 to Form F-6 Registration Sta

Certification under Rule 466

Certification under Rule 466 The depositary, JPMorgan Chase Bank, N.A., represents and certifies the following: (1) That it previously had filed a registration statement on Form F-6 (Eisai Co., Ltd., 333-269160) that the Commission declared effective, with terms of deposit identical to the terms of deposit of this registration statement. (2) That its ability to designate the date and time of effec

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM F-6 REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Shionogi & Co., Ltd. (Exac

333-235099 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Shionogi & Co., Ltd. (Exact name of Issuer of deposited securities as specified in its charter) Japan (Jurisdiction of Incorporation or organization of Issuer)

JPMorgan Chase Bank, N.A. American Depositary Receipt American Depositary Shares Representing Shares of Common Stock of Shionogi & Co., Ltd. (the "Issuer") (Incorporated under the laws of Japan)

SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

As filed with the Securities and Exchange Commission on September 18, 2024 Registration No. 333-154899 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST EFFECTIVE AMENDMENT NO. 2 TO THE FORM F-6 REGISTRATION STATEMENT THE SECURITIES ACT

As filed with the Securities and Exchange Commission on September 18, 2024 Registration No.

THE BANK OF NEW YORK MELLON FORM OF AMERICAN DEPOSITARY RECEIPT STATEMENT OF TERMS AND CONDITIONS WITH RESPECT TO AMERICAN DEPOSITARY SHARES COMMON STOCK OF SHIONOGI & CO., LTD. (THE “COMPANY”) (INCORPORATED UNDER THE LAWS OF JAPAN)

Note: The following Form of Receipt and Statement of Terms and Conditions amends the ratio of ADSs to Shares to 2 ADSs to 1 Share and also amends and updates the terms and conditions of the American Depositary Shares in various other respects.

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts SHIONOGI & CO., LTD. (Exact name of issuer of deposited secu

Registration No. 333- As filed with the Securities and Exchange Commission August 17, 2022 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts SHIONOGI & CO., LTD. (Exact name of issuer of deposited securities as specified in its charter) Japan (Jurisdicti

The Chrysler Building

Exhibit (d) The Chrysler Building 405 Lexington Avenue, NY, NY 10174-1299 Tel: 212.

Deutsche Bank Trust Company Americas American Depositary Receipt American Depositary Shares Representing Shares of Common Stock of Shionogi & Co., Ltd. (Incorporated under the laws of Japan)

SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

Certification under Rule 466

Exhibit (e) Certification under Rule 466 The depositary, Deutsche Bank Trust Company Americas, represents and certifies the following: (1) That it previously had filed a registration statement on Form F-6 (Hochtief AG, 333-228091), which the U.

ENTA / Enanta Pharmaceuticals, Inc. / SHIONOGI & CO LTD - SC 13G/A Passive Investment

SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Enanta Pharmaceuticals, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 29251M106 (CUSIP Number) December 31, 2019 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant

DMLRY / Daimler AG F-6EF - -

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Shionogi & Co., Ltd. (Exact name of Issuer of deposited securities as specified in its charter) Japan (Jurisdiction of Incorporation or organization of Issuer) JPMorgan Chase Bank, N.A. (Exact name of dep

Certification under Rule 466

Certification under Rule 466 The depositary, JPMorgan Chase Bank, N.A., represents and certifies the following: (1) That it previously had filed a registration statement on Form F-6 (Softbank Mobile Service Corp., 333-229175) that the Commission declared effective, with terms of deposit identical to the terms of deposit of this registration statement. (2) That its ability to designate the date and

Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, Suite 2405 New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 October 15, 2019

Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, Suite 2405 New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 October 15, 2019 JPMorgan Chase Bank, N.

JPMorgan Chase Bank, N.A. American Depositary Receipt American Depositary Shares Representing Shares of Common Stock of Shionogi & Co., Ltd. (Incorporated under the laws of Japan)

SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

AUKUF / AMS AG F-6 POS

F-6 POS 1 tv515645f6pos.htm F-6 POS Number: 333-225888 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Shionogi & Co., Ltd. (Exact name of Issuer of deposited securities as specified in its charter) Japan (Jurisdiction

Deutsche Bank Trust Company Americas American Depositary Receipt American Depositary Shares For Shares of Common Stock of Shionogi & Co., Ltd. (Incorporated under the laws of Japan)

Exhibit (a) SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

Certification under Rule 466

Exhibit (e) Certification under Rule 466 The depositary, Deutsche Bank Trust Company Americas, represents and certifies the following: (1) That it previously had filed a registration statement on Form F-6 (Hochtief AG, 333-228091), which the U.

THLEY / THALES F-6 POS

As filed with the Securities and Exchange Commission on February 21, 2019 Registration No.

AMERICAN DEPOSITARY RECEIPT

EX-99.(A) 2 e618249ex99-a.htm Exhibit (a) NUMBER AMERICAN DEPOSITARY SHARES CUSIP # Each American Depositary Share represents one-fourth (1/4) of one share of common stock of the Company SUBSCRIPTION RIGHTS: Under Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current m

Rule 466 Certification

Exhibit (e) Rule 466 Certification The depositary, Citibank, N.A., represents and certifies the following: 1. That it previously had filed a registration statement on Form F-6 (Registration No. 333-202848), which the U.S. Securities and Exchange Commission declared effective, with terms of deposit identical to the terms of deposit of this Post-Effective Amendment No. 1 to Form F-6 Registration Sta

Certification under Rule 466

Certification under Rule 466 The depositary, JPMorgan Chase Bank, N.A., represents and certifies the following: (1) That it previously had filed a registration statement on Form F-6 (Softbank Mobile Service Corp., 333-229175) that the Commission declared effective, with terms of deposit identical to the terms of deposit of this registration statement. (2) That its ability to designate the date and

DMLRY / Daimler AG F-6 POS

F-6 POS 1 e618246f6pos-shionogi.htm 333-210908 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 POST-EFFECTIVE AMENDMENT NO. 1 TO FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Shionogi & Co., Ltd. (Exact name of Issuer of deposited securities as specified in its charter) Japan (Jurisdiction of Inco

JPMorgan Chase Bank, N.A. American Depositary Receipt American Depositary Shares Representing Shares of Common Stock of Shionogi & Co., Ltd. (Incorporated under the laws of Japan)

SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

LZRFY / Localiza Rent A Car SA F-6 POST EFFECTIVE AMENDMENT NO. 1 TO THE FORM F-6

As filed with the Securities and Exchange Commission on February 15, 2019 Registration No.

THE BANK OF NEW YORK MELLON FORM OF AMERICAN DEPOSITARY RECEIPT STATEMENT OF TERMS AND CONDITIONS WITH RESPECT TO AMERICAN DEPOSITARY SHARES SHARES OF COMMON STOCK, OF SHIONOGI & CO., LTD. (THE “COMPANY”) (INCORPORATED UNDER THE LAWS OF JAPAN)

EX-1 2 shionogireceipt.htm FORM OF RECEIPT AMERICAN DEPOSITARY SHARES (One (1) American Depositary Share represents One Fourth (1/4) of One Share) THE BANK OF NEW YORK MELLON FORM OF AMERICAN DEPOSITARY RECEIPT AND STATEMENT OF TERMS AND CONDITIONS WITH RESPECT TO AMERICAN DEPOSITARY SHARES REPRESENTING SHARES OF COMMON STOCK, OF SHIONOGI & CO., LTD. (THE “COMPANY”) (INCORPORATED UNDER THE LAWS OF

Certification under Rule 466

Certification under Rule 466 The depositary, Deutsche Bank Trust Company Americas, represents and certifies the following: (1) That it previously had filed a registration statement on Form F-6 (Sumitomo Metal Mining Co.

Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, Suite 2405 New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 June 26, 2018

Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, Suite 2405 New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 June 26, 2018 Deutsche Bank Trust Company Americas, as Depositary 60 Wall Street New York, New York 10005 American Depositary Shares evidenced by American Depositary Receipts for deposited shares of the foreign private issuer whose name appears on t

AUKUF / AMS AG F-6EF

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Shionogi & Co., Ltd. (Exact name of Issuer of deposited securities as specified in its charter) Japan (Jurisdiction of Incorporation or organization of Issuer) DEUTSCHE BANK TRUST COMPANY AMERICAS (Exact

THE RELEASE OF THE SHARES OF STOCK OF THE ISSUER (AS HEREINAFTER DEFINED) UNDERLYING THE ADSs REPRESENTED BY THIS ADR MAY BE LIMITED TO A UNIT OF SUCH NUMBER OF SHARES OF STOCK AS THE ARTICLES OF INCORPORATION MAY FROM TIME TO TIME DESIGNATE AS A "UN

EX-99.(A) 2 e618135ex99-a.htm SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security. In the absence of registration under United States Securities Act of 1933 of such rights the Depositary intends to endea

Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, Suite 2405 New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 April 18, 2016

Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, Suite 2405 New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 April 18, 2016 JPMorgan Chase Bank, N.

THE RELEASE OF THE SHARES OF STOCK OF THE ISSUER (AS HEREINAFTER DEFINED) UNDERLYING THE ADSs REPRESENTED BY THIS ADR MAY BE LIMITED TO A UNIT OF SUCH NUMBER OF SHARES OF STOCK AS THE ARTICLES OF INCORPORATION MAY FROM TIME TO TIME DESIGNATE AS A "UN

EX-99.(A) 2 e614959ex99-a.htm SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security. In the absence of registration under United States Securities Act of 1933 of such rights the Depositary intends to endea

Shionogi F

F-6EF 1 e614959f6ef-shionogi.htm SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts Shionogi & Co., Ltd. (Exact name of Issuer of deposited securities as specified in its charter) Japan (Jurisdiction of Incorporation or organization of Issuer) JPMorgan Ch

Certification under Rule 466

EX-99.(E) 4 e614959ex99-e.htm Certification under Rule 466 The depositary, JPMorgan Chase Bank, N.A., represents and certifies the following: (1) That it previously had filed a registration statement on Form F-6 (The Shizuoka Bank Ltd, 333-209985) that the Commission declared effective, with terms of deposit identical to the terms of deposit of this registration statement. (2) That its ability to

EGLT / Egalet Corporation / SHIONOGI & CO LTD - SCHEDULE 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13D/A (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULE 13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(a) UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 2)* EGALET CORPORATION (Name of Issuer) Common Stock, par value $0.001 per Share (Title of Class of Securities) 2

Rule 466 Certification

Exhibit (e) Rule 466 Certification The depositary, Citibank, N.A., represents and certifies the following: 1. That it previously had filed a registration statement on Form F-6 (Registration No. 333-202848), which the U.S. Securities and Exchange Commission declared effective, with terms of deposit identical to the terms of deposit of this Form F-6 Registration Statement (except for the name of the

As filed with the Securities and Exchange Commission on August 4, 2015 Registration No. 333-_____

As filed with the Securities and Exchange Commission on August 4, 2015 Registration No.

AMERICAN DEPOSITARY SHARES

EX-99.(A) 2 e613963ex99-a.htm Exhibit (a) NUMBER AMERICAN DEPOSITARY SHARES CUSIP # Each American Depositary Share represents two (2) shares of common stock of the Company SUBSCRIPTION RIGHTS: Under Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of

LETTERHEAD OF PATTERSON BELKNAP WEBB & TYLER LLP

Exhibit (d) LETTERHEAD OF PATTERSON BELKNAP WEBB & TYLER LLP August 4, 2015 Citibank, N.

EGLT / Egalet Corporation / SHIONOGI & CO LTD - FORM SC 13D/A Activist Investment

SC 13D/A 1 dp47799sc13da.htm FORM SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13D/A (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULE 13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(a) UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1)* EGALET CORPORATION (Name of Issuer) Common Stock, par value $0.001

JOINT FILING AGREEMENT

EX-99.4 3 dp43961ex04.htm EXHIBIT 4 EXHIBIT 4 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a statement on Schedule 13D (including amendments thereto) with respect to the common stock of Egalet Corporation, par value $0.001 per share, and further agree tha

EGLT / Egalet Corporation / SHIONOGI & CO LTD - FORM SC 13D Activist Investment

SC 13D 1 dp43961sc13d.htm FORM SC 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 EGALET CORPORATION (Name of Issuer) Common Stock, par value $0.001 per Share (Title of Class of Securities) 28226B104 (CUSIP Number) Shinya Matsuzawa Corporate Officer, Vice President Legal Affairs Department Shionogi & Co., Ltd. 1-8,

lock-up agreement

EXHIBIT 3 lock-up agreement Egalet Corporation 101 Lindenwood Drive Suite 225 Malvern, PA 19355 Stifel, Nicolaus & Company, Incorporated JMP Securities LLC c/o Stifel, Nicolaus & Company, Incorporated 787 7th Avenue, 11th Floor New York, New York 10019 Ladies and Gentlemen: The undersigned refers to the proposed Underwriting Agreement (the “Underwriting Agreement”) among Egalet Corporation, a Delaware corporation (the “Company”), and the several underwriters named therein (the “Underwriters”).

ENTA / Enanta Pharmaceuticals, Inc. / SHIONOGI & CO LTD - SC 13G Passive Investment

SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Enanta Pharmaceuticals, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 29251M106 (CUSIP Number) March 26, 2013 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to wh

As filed with the Securities and Exchange Commission on October 31, 2008 Registration No. 333- SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 For Depositary Shares Evidenced by Ame

F-6EF 1 shionogiunsponsoredformf6.htm FORM F-6 As filed with the Securities and Exchange Commission on October 31, 2008 Registration No. 333- SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT under THE SECURITIES ACT OF 1933 For Depositary Shares Evidenced by American Depositary Receipts of SHIONOGI & CO., LTD. (Exact name of issuer of deposited securities a

EMMET, MARVIN & MARTIN, LLP COUNSELLORS AT LAW 120 Broadway New York, New York 10271 (212) 238-3000 (212) 653-1760 Fax: (212) 238-3100 Fax: (212) 653-1730

EX-4 3 shionogiunsponsoredopinionex.htm OPINION OF COUNSEL EXHIBIT 4 Writer’s Direct Dial EMMET, MARVIN & MARTIN, LLP COUNSELLORS AT LAW 120 Broadway New York, New York 10271 (212) 238-3000 (212) 653-1760 Fax: (212) 238-3100 Fax: (212) 653-1730 http://www.emmetmarvin.com 177 MADISON AVENUE MORRISTOWN, NEW JERSEY 07960 (973) 538-5600 FAX: (973) 538-6448 1351 WASHINGTON BOULEVARD STAMFORD, CONNECTIC

THE BANK OF NEW YORK MELLON AMERICAN DEPOSITARY RECEIPT FOR COMMON STOCK, NO PAR VALUE, OF SHIONOGI & CO., LTD. (INCORPORATED UNDER THE LAWS OF JAPAN)

EX-1 2 shionogireceipt.htm FORM OF RECEIPT AMERICAN DEPOSITARY SHARES (One (1) American Depositary Share represents Two (2) Shares) THE BANK OF NEW YORK MELLON AMERICAN DEPOSITARY RECEIPT FOR COMMON STOCK, NO PAR VALUE, OF SHIONOGI & CO., LTD. (INCORPORATED UNDER THE LAWS OF JAPAN) The Bank of New York Mellon, as depositary (hereinafter called the “Depositary”), hereby certifies (i) that there hav

Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, 44th Floor New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 October 6, 2008

Exhibit 99(d) Ziegler, Ziegler & Associates LLP Counselors at Law 570 Lexington Avenue, 44th Floor New York, New York 10022 (212) 319-7600 Telecopier (212) 319-7605 October 6, 2008 Deutsche Bank Trust Company Americas, as Depositary 60 Wall Street New York, New York 10005 American Depositary Shares evidenced by American Depositary Receipts for deposited shares of the foreign private issuer whose n

Certification under Rule 466

Exhibit 99(e) Certification under Rule 466 The depositary, Deutsche Bank Trust Company Americas, represents and certifies the following: (1) That it previously had filed a registration statement on Form F-6 (Premier Farnell plc 333-153746) that the Commission declared effective, with terms of deposit identical to the terms of deposit of this registration statement.

Number

Exhibit 99(a) SUBSCRIPTION RIGHTS: Under current Japanese practice offerings of rights to subscribe to additional underlying securities are sometimes made, and in varying amounts, with a subscription price sometimes below the current market price of the security.

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts SHIONOGI & CO., LTD. (Exact name of Issuer of deposited secu

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT Under THE SECURITIES ACT OF 1933 For American Depositary Shares Evidenced by American Depositary Receipts SHIONOGI & CO., LTD. (Exact name of Issuer of deposited securities as specified in its charter) Japan (Jurisdiction of Incorporation or organization of Issuer) DEUTSCHE BANK TRUST COMPANY AMERICAS (Exact