JNCE / Jounce Therapeutics Inc - تصريحات هيئة الأوراق المالية والبورصات، التقرير السنوي، بيان الوكيل

شركة جونس ثيرابيوتيكس
US ˙ NASDAQ ˙ US4811161011
هذا الرمز لم يعد نشطا

الإحصائيات الأساسية
LEI 5493004MZJQIV2K8ZT61
CIK 1640455
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Jounce Therapeutics Inc
SEC Filings (Chronological Order)
توفر هذه الصفحة قائمة كاملة ومرتبة ترتيبًا زمنيًا لتصريحات هيئة الأوراق المالية والبورصات، باستثناء تصريحات الملكية التي نقدمها في مكان آخر.
February 14, 2024 SC 13G/A

JNCE / Jounce Therapeutics Inc / Deep Track Capital, LP Passive Investment

SC 13G/A 1 deeptrack-jnce123123a3.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 3)* JOUNCE THERAPEUTICS, INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 481116101 (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of this Statement) Ch

February 9, 2024 SC 13G

JNCE / Jounce Therapeutics Inc / Opaleye Management Inc. Passive Investment

SC 13G 1 formsc13g.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Jounce Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 481116101 (CUSIP Number) James Silverman, One Boston Place, 26th Floor, Boston, MA 02108 (Name, Address and Telephone Number of Person

February 2, 2024 SC 13G/A

JNCE / Jounce Therapeutics Inc / Cowen Financial Products LLC - COWEN FINANCIAL PRODUCTS LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Jounce Therapeutics Inc. (Name of Issuer) common stock (Title of Class of Securities) 481116101 (CUSIP Number) December 29, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which thi

May 15, 2023 15-12G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13 AND 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. 001-37998 Commission File Number JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in

May 5, 2023 SC 13D/A

JNCE / Jounce Therapeutics Inc / TANG CAPITAL PARTNERS LP - AMENDMENT NO. 4 Activist Investment

SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13D/A Under the securities exchange act of 1934 (amendment no.

May 4, 2023 EX-10.1

Lease Termination Agreement, by and between the Company and the Landlord, dated May 2, 2023.

Exhibit 10.1 AGREEMENT FOR TERMINATION OF LEASE AND VOLUNTARY SURRENDER OF PREMISES This Agreement for Termination of Lease and Voluntary Surrender of Premises (this “Agreement”) is made and entered into as of May 2, 2023 (the “Effective Date”), by and between ARE-770/784/790 MEMORIAL DRIVE, LLC, a Delaware limited liability company (“Landlord”), and JOUNCE THERAPEUTICS, INC., a Delaware corporati

May 4, 2023 S-8 POS

As filed with the Securities and Exchange Commission on May 4, 2023

As filed with the Securities and Exchange Commission on May 4, 2023 Registration No.

May 4, 2023 EX-3.2

Amended and Restated Bylaws of Jounce Therapeutics, Inc.

Exhibit 3.2 BYLAWS OF JOUNCE THERAPEUTICS, INC. (a Delaware corporation) (Adopted as of March 3, 2023) Article I CORPORATE OFFICES Section 1.1Registered Office. The registered office of the Corporation shall be fixed in the Certificate of Incorporation of the Corporation. Section 1.2Other Offices. The Corporation may also have an office or offices, and keep the books and records of the Corporation

May 4, 2023 POS AM

As filed with the Securities and Exchange Commission on May 4, 2023

As filed with the Securities and Exchange Commission on May 4, 2023 Registration No.

May 4, 2023 S-8 POS

As filed with the Securities and Exchange Commission on May 4, 2023

As filed with the Securities and Exchange Commission on May 4, 2023 Registration No.

May 4, 2023 S-8 POS

As filed with the Securities and Exchange Commission on May 4, 2023

As filed with the Securities and Exchange Commission on May 4, 2023 Registration No.

May 4, 2023 SC TO-T/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(d)(1) OR 13(e)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 3) JOUNCE THERAPEUTICS, INC. (Name of Subject Company

SC TO-T/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(d)(1) OR 13(e)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 3) JOUNCE THERAPEUTICS, INC. (Name of Subject Company (Issuer)) CONCENTRA MERGER SUB, INC. (Name of Filing Persons (Co-Offeror 1)) CONCENTRA BIOSCIENCES, LLC (Name of Filing Persons (Co-Offeror

May 4, 2023 S-8 POS

As filed with the Securities and Exchange Commission on May 4, 2023

As filed with the Securities and Exchange Commission on May 4, 2023 Registration No.

May 4, 2023 EX-99.(D)(5)

Contingent Value Rights Agreement, dated May 3, 2023, by and among Parent, Purchaser, the Rights Agent and the Representative (incorporated by reference to Exhibit (a)(1)(G) to the Schedule TO-T/A filed by Merger Sub with the SEC on May 4, 2023)

EX-99.(d)(5) Exhibit (d)(5) CONTINGENT VALUE RIGHTS AGREEMENT THIS CONTINGENT VALUE RIGHTS AGREEMENT, dated as of May 3, 2023 (this “Agreement”), is entered into by and between Concentra Biosciences, LLC, a Delaware limited liability company (the “Parent”), Concentra Merger Sub, Inc., a Delaware corporation and a wholly owned Subsidiary of Parent (the “Purchaser”), Computershare Inc., a Delaware c

May 4, 2023 EX-FILING FEES

Calculation of Filing Fee Tables SC TO-T (Form Type) Jounce Therapeutics, Inc. (Name of Subject Company – Issuer) Concentra Merger Sub, Inc. (Names of Filing Persons — Co-Offeror 1) Concentra Biosciences, LLC (Names of Filing Persons — Co-Offeror 2)

EX-FILING FEES Exhibit 107 Calculation of Filing Fee Tables SC TO-T (Form Type) Jounce Therapeutics, Inc.

May 4, 2023 POS AM

As filed with the Securities and Exchange Commission on May 4, 2023

As filed with the Securities and Exchange Commission on May 4, 2023 Registration No.

May 4, 2023 S-8 POS

As filed with the Securities and Exchange Commission on May 4, 2023

As filed with the Securities and Exchange Commission on May 4, 2023 Registration No.

May 4, 2023 SC 14D9/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) (Amendment No. 2) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 Jounce Therapeutics, Inc. (Nam

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) (Amendment No. 2) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 Jounce Therapeutics, Inc. (Name of Subject Company) Jounce Therapeutics, Inc. (Name of Person(s) Filing Statement) Common Stock, $0.001 par value per share (Title of Class of Secur

May 4, 2023 S-8 POS

As filed with the Securities and Exchange Commission on May 4, 2023

As filed with the Securities and Exchange Commission on May 4, 2023 Registration No.

May 4, 2023 S-8 POS

As filed with the Securities and Exchange Commission on May 4, 2023

As filed with the Securities and Exchange Commission on May 4, 2023 Registration No.

May 4, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 2, 2023 JOUNCE THERAPEUTICS,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 2, 2023 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission F

May 4, 2023 EX-99.1

Press release issued by Company on May 3, 2023.

Exhibit 99.1 Jounce Therapeutics Announces Closing of Tender Offer Stockholders to Receive $1.85 Per Share in Cash Plus Contingent Value Rights CAMBRIDGE, Mass., May 3, 2023-(GLOBE NEWSWIRE) – Jounce Therapeutics, Inc. (NASDAQ: JNCE) (“Jounce” or the “Company”), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today announ

May 4, 2023 EX-3.1

Amended and Restated Certificate of Incorporation of Jounce Therapeutics, Inc.

Exhibit 3.1 FIFTH AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF JOUNCE THERAPEUTICS, INC. I. The name of this corporation is Jounce Therapeutics, Inc. (the “Corporation”). II. The registered office of the corporation in the State of Delaware shall be Corporation Trust Center, 1209 Orange Street, City of Wilmington, County of New Castle, Zip Code 19801, and the name of the registered agent o

April 28, 2023 EX-99.(A)(1)(G)

Supplement No. 2 to the Offer to Purchase, dated April 28, 2023 (incorporated by reference to Exhibit (a)(1)(G) to the Schedule TO-T/A filed by Merger Sub with the SEC on April 28, 2023)

EX-99.(a)(1)(G) Exhibit (a)(1)(G) Supplement No. 2 to Offer to Purchase All Outstanding Shares of Common Stock of JOUNCE THERAPEUTICS, INC. At $1.85 per Share in Cash, Plus One Non-Transferable Contractual Contingent Value Right for Each Share (“CVR”), Which Represents the Right to Receive One or More Payments in Cash, Contingent upon Receipt of Proceeds from Disposition of CVR Products during the

April 28, 2023 10-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K/A (Amendment No. 1)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K/A (Amendment No. 1) (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001

April 28, 2023 SC TO-T/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(d)(1) OR 13(e)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 2) JOUNCE THERAPEUTICS, INC. (Name of Subject Company

SC TO-T/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(d)(1) OR 13(e)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 2) JOUNCE THERAPEUTICS, INC. (Name of Subject Company (Issuer)) CONCENTRA MERGER SUB, INC. (Name of Filing Persons (Co-Offeror 1)) CONCENTRA BIOSCIENCES, LLC (Name of Filing Persons (Parent of C

April 25, 2023 EX-99.(A)(1)(E)

Supplement to the Offer to Purchase, dated April 25, 2023 (incorporated by reference to Exhibit (a)(1)(E) to the Schedule TO-T/A filed by Merger Sub with the SEC on April 25, 2023)

EX-99.(a)(1)(E) Exhibit (a)(1)(E) Supplement to Offer to Purchase All Outstanding Shares of Common Stock of JOUNCE THERAPEUTICS, INC. At $1.85 per Share in Cash, Plus One Non-Transferable Contractual Contingent Value Right for Each Share (“CVR”), Which Represents the Right to Receive One or More Payments in Cash, Contingent upon Receipt of Proceeds from Disposition of CVR Products during the Dispo

April 25, 2023 EX-99.(A)(1)(F)

Amended and Restated Offer to Purchase, dated April 25, 2023 (incorporated by reference to Exhibit (a)(1)(F) to the Schedule TO-T/A filed by Merger Sub with the SEC on April 25, 2023)

EX-99.(a)(1)(F) Exhibit (a)(1)(F) Amended and Restated Offer to Purchase All Outstanding Shares of Common Stock of JOUNCE THERAPEUTICS, INC. At $1.85 per Share in Cash, Plus One Non-Transferable Contractual Contingent Value Right for Each Share (“CVR”), Which Represents the Right to Receive One or More Payments in Cash, Contingent upon Receipt of Proceeds from Disposition of CVR Products during th

April 25, 2023 SC TO-T/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(d)(1) OR 13(e)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1) JOUNCE THERAPEUTICS, INC. (Name of Subject Company

SC TO-T/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(d)(1) OR 13(e)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1) JOUNCE THERAPEUTICS, INC. (Name of Subject Company (Issuer)) CONCENTRA MERGER SUB, INC. (Name of Filing Persons (Co-Offeror 1)) CONCENTRA BIOSCIENCES, LLC (Name of Filing Persons (Parent of C

April 24, 2023 CORRESP

* * *

April 24, 2023 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Mergers & Acquisitions 100 F Street, N.E. Washington, D.C. 20549 Attention: Christina Chalk and Blake Grady Re: Jounce Therapeutics, Inc. Schedule 14D-9 filed April 6, 2023 File No. 005-89831 Ladies and Gentlemen: On behalf of Jounce Therapeutics, Inc. (the “Company”), we are writing in respo

April 24, 2023 SC 14D9/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) (Amendment No. 1) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 Jounce Therapeutics, Inc. (Nam

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) (Amendment No. 1) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 Jounce Therapeutics, Inc. (Name of Subject Company) Jounce Therapeutics, Inc. (Name of Person(s) Filing Statement) Common Stock, $0.001 par value per share (Title of Class of Secur

April 12, 2023 SC 13G

JNCE / Jounce Therapeutics Inc / Opaleye Management Inc. Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Jounce Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 481116101 (CUSIP Number) James Silverman, One Boston Place, 26th Floor, Boston, MA 02108 (Name, Address and Telephone Number of Person Authorized to Receive N

April 7, 2023 SC 13D/A

JNCE / Jounce Therapeutics Inc / TANG CAPITAL PARTNERS LP - AMENDMENT NO. 3 Activist Investment

SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13D/A Under the securities exchange act of 1934 (amendment no.

April 6, 2023 SC 14D9

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 Jounce Therapeutics, Inc. (Name of Subject Compa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 Jounce Therapeutics, Inc. (Name of Subject Company) Jounce Therapeutics, Inc. (Name of Person Filing Statement) Common Stock, $0.001 par value per share (Title of Class of Securities) 481116101 (CUS

April 5, 2023 EX-99.(A)(1)(D)

Form of Letter to Clients for Use by Brokers, Dealers, Commercial Banks, Trust Companies and Other Nominees (incorporated by reference to Exhibit (a)(1)(D) to the Schedule TO filed by Merger Sub with the SEC on April 5, 2023)

EX-99.(a)(1)(D) Exhibit (a)(1)(D) Offer to Purchase All Outstanding Shares of Common Stock of JOUNCE THERAPEUTICS, INC. a Delaware corporation at $1.85 PER SHARE IN CASH, PLUS ONE NON-TRANSFERABLE CONTRACTUAL CONTINGENT VALUE RIGHT (“CVR”) FOR EACH SHARE, WHICH REPRESENTS THE RIGHT TO RECEIVE ONE OR MORE PAYMENTS IN CASH, CONTINGENT UPON RECEIPT OF PROCEEDS FROM THE DISPOSITION OF CVR PRODUCTS DUR

April 5, 2023 EX-99.(A)(1)(B)

Form of Letter of Transmittal (incorporated by reference to Exhibit (a)(1)(B) to the Schedule TO filed by Merger Sub with the SEC on April 5, 2023)

EX-99.(a)(1)(B) Exhibit (a)(1)(B) Letter of Transmittal To Tender Shares of Common Stock of JOUNCE THERAPEUTICS, INC. a Delaware corporation at $1.85 PER SHARE IN CASH, PLUS ONE NON-TRANSFERABLE CONTRACTUAL CONTINGENT VALUE RIGHT FOR EACH SHARE Pursuant to the Offer to Purchase Dated April 5, 2023 by CONCENTRA MERGER SUB, INC. a wholly owned subsidiary of CONCENTRA BIOSCIENCES, LLC THE OFFER AND W

April 5, 2023 EX-FILING FEES

Calculation of Filing Fee Tables SC TO-T (Form Type) Jounce Therapeutics, Inc. (Name of Subject Company – Issuer) Concentra Merger Sub, Inc. (Names of Filing Persons — Offeror) Concentra Biosciences, LLC (Names of Filing Persons — Parent of Offeror)

EX-FILING FEES Exhibit 107 Calculation of Filing Fee Tables SC TO-T (Form Type) Jounce Therapeutics, Inc.

April 5, 2023 EX-99.(D)(4)

Equity Commitment and Guarantee Letter, dated March 26, 2023, by TCP in favor of Concentra and TCP (incorporated by reference to Exhibit (d)(3) to the Schedule TO filed by Merger Sub with the SEC on April 5, 2023)

EX-99.(d)(4) Exhibit (d)(4) TANG CAPITAL PARTNERS, LP 4747 EXECUTIVE DRIVE, SUITE 210, SAN DIEGO, CA 92121 (858) 200-3830 FAX (858) 200-3837 Equity Commitment and Guarantee Letter March 26, 2023 Michael Hearne, Chief Financial Officer Concentra Biosciences, LLC 4747 Executive Drive, Suite 210 San Diego, CA 92121 Dear Mr. Hearne: Reference is made to the Agreement and Plan of Merger, dated as of th

April 5, 2023 SC TO-T

Schedule TO (incorporated by reference to that certain Schedule TO filed by Merger Sub with the SEC on April 5, 2023)

SC TO-T UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(d)(1) OR 13(e)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 JOUNCE THERAPEUTICS, INC. (Name of Subject Company (Issuer)) CONCENTRA MERGER SUB, INC. (Name of Filing Persons (Offeror)) CONCENTRA BIOSCIENCES, LLC (Name of Filing Persons (Parent of Offeror)) Common Stock, Pa

April 5, 2023 EX-99.(A)(1)(C)

Form of Letter to Brokers, Dealers, Commercial Banks, Trust Companies and Other Nominees (incorporated by reference to Exhibit (a)(1)(C) to the Schedule TO filed by Merger Sub with the SEC on April 5, 2023)

EX-99.(a)(1)(C) Exhibit (a)(1)(C) Offer to Purchase All Outstanding Shares of Common Stock of JOUNCE THERAPEUTICS, INC. a Delaware corporation at $1.85 PER SHARE IN CASH, PLUS ONE NON-TRANSFERABLE CONTRACTUAL CONTINGENT VALUE RIGHT (“CVR”) FOR EACH SHARE, WHICH REPRESENTS THE RIGHT TO RECEIVE ONE OR MORE PAYMENTS IN CASH, CONTINGENT UPON RECEIPT OF PROCEEDS FROM THE DISPOSITION OF CVR PRODUCTS DUR

April 5, 2023 EX-99.(D)(2)

Confidentiality Agreement, dated March 15, 2023, between Jounce, Parent and TCP (incorporated herein by reference to Exhibit (d)(2) to the Schedule TO).

EX-99.(d)(2) Exhibit (d)(2) MUTUAL CONFIDENTIALITY AGREEMENT THIS MUTUAL CONFIDENTIALITY AGREEMENT (the “Agreement”) is made as of March 15, 2023 (the “Effective Date”) by and between Jounce Therapeutics, Inc., a Delaware corporation with an office at 780 Memorial Drive, Cambridge, MA 02139 (“Jounce”) and Concentra Biosciences, LLC, a Delaware limited liability company and its controlling sharehol

April 5, 2023 EX-99.(A)(1)(A)

Offer to Purchase, dated April 5, 2023 (incorporated by reference to Exhibit (a)(1)(A) to the Schedule TO filed by Merger Sub with the SEC on April 5, 2023)

EX-99.(a)(1)(A) Table of Contents Exhibit (a)(1)(A) Offer to Purchase All Outstanding Shares of Common Stock of JOUNCE THERAPEUTICS, INC. At $1.85 per Share in Cash, Plus One Non-Transferable Contractual Contingent Value Right for Each Share (“CVR”), Which Represents the Right to Receive One or More Payments in Cash, Contingent upon Receipt of Proceeds from Disposition of CVR Products during the D

April 3, 2023 SC14D9C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 SOLICITATION/RECOMMENDATION STATEMENT PURSUANT TO SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 JOUNCE THERAPEUTICS, INC. (Name of Subject Company) JOUNC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 SOLICITATION/RECOMMENDATION STATEMENT PURSUANT TO SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 JOUNCE THERAPEUTICS, INC. (Name of Subject Company) JOUNCE THERAPEUTICS, INC. (Name of Person(s) Filing Statement) Common Stock, $0.001 par value per share (Title of Class of Securities) 481116101 (CUSIP Num

April 3, 2023 EX-99.1

Press release, dated April 3, 2023, issued by the Company.

Exhibit 99.1 NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OF SUCH JURISDICTION. Termination of Proposed Business Combination of Jounce Therapeutics, Inc. and Redx Pharma plc CAMBRIDGE, Mass., April 3, 2023 – Jounce Therapeutics, Inc. ("Jounce" or the "Company") and Red

March 30, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 26, 2023 JOUNCE THERAPEUTIC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 26, 2023 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commissio

March 28, 2023 SC 13D/A

JNCE / Jounce Therapeutics Inc / TANG CAPITAL PARTNERS LP - AMENDMENT NO. 2 Activist Investment

SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13D/A Under the securities exchange act of 1934 (amendment no.

March 27, 2023 EX-99.1

Press release, dated March 27, 2023, issued by the Company.

Exhibit 99.1 NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OF SUCH JURISDICTION. Jounce Therapeutics Enters Into Agreement to Be Acquired by Concentra Biosciences for $1.85 in Cash per Share Plus Contingent Value Rights CAMBRIDGE, Mass., March 27, 2023 – Jounce Therapeu

March 27, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 26, 2023 JOUNCE THERAPEUTIC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 26, 2023 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commissio

March 27, 2023 SC 14D9

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 SOLICITATION/RECOMMENDATION STATEMENT PURSUANT TO SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 JOUNCE THERAPEUTICS, INC. (Name of Subject Company) JOUNC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 SOLICITATION/RECOMMENDATION STATEMENT PURSUANT TO SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 JOUNCE THERAPEUTICS, INC. (Name of Subject Company) JOUNCE THERAPEUTICS, INC. (Name of Person(s) Filing Statement) Common Stock, $0.001 par value per share (Title of Class of Securities) 481116101 (CUSIP Num

March 27, 2023 EX-2.1

Agreement and Plan of Merger, dated March 26, 2023, by and among Jounce Therapeutics, Inc., Concentra Biosciences, LLC and Concentra Merger Sub, Inc. (incorporated by reference to Exhibit 2.1 to the Issuer’s Current Report on Form 8-K filed with the SEC on March 27, 2023) (previously filed)

Exhibit 2.1 AGREEMENT AND PLAN OF MERGER among CONCENTRA BIOSCIENCES, LLC, CONCENTRA MERGER SUB, INC. and JOUNCE THERAPEUTICS, INC. Dated as of March 26, 2023 TABLE OF CONTENTS Page Article I THE OFFER 2 Section 1.1 The Offer 2 Section 1.2 Offer Documents 3 Section 1.3 Company Actions 4 Article II THE MERGER 5 Section 2.1 The Merger 5 Section 2.2 Closing 5 Section 2.3 Effective Time 5 Section 2.4

March 27, 2023 EX-99.1

NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OF SUCH JURISDICTION.

Exhibit 99.1 NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OF SUCH JURISDICTION. Jounce Therapeutics Enters Into Agreement to Be Acquired by Concentra Biosciences for $1.85 in Cash per Share Plus Contingent Value Rights CAMBRIDGE, Mass., March 27, 2023 – Jounce Therapeu

March 17, 2023 SC 13D/A

JNCE / Jounce Therapeutics Inc / TANG CAPITAL PARTNERS LP - AMENDMENT NO. 1 Activist Investment

SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13D/A Under the securities exchange act of 1934 (amendment no.

March 15, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 14, 2023 JOUNCE THERAPEUTIC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 14, 2023 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commissio

March 15, 2023 EX-99.1

Press Release of the Company dated March 14, 2023

Exhibit 99.1 NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OF SUCH JURISDICTION. Jounce Therapeutics Confirms Receipt of Unsolicited Proposal from Concentra Biosciences CAMBRIDGE, Mass., March. 14, 2023 – The Board of Directors (the “Board”) of Jounce Therapeutics, Inc.

March 15, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 14, 2023 JOUNCE THERAPEUTIC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 14, 2023 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commissio

March 15, 2023 EX-99.1

Jounce Therapeutics Confirms Receipt of Unsolicited Proposal from Concentra Biosciences

Exhibit 99.1 NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OF SUCH JURISDICTION. Jounce Therapeutics Confirms Receipt of Unsolicited Proposal from Concentra Biosciences CAMBRIDGE, Mass., March. 14, 2023 – The Board of Directors (the “Board”) of Jounce Therapeutics, Inc.

March 14, 2023 SC 13D

JNCE / Jounce Therapeutics Inc / TANG CAPITAL PARTNERS LP Activist Investment

SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13D Under the securities exchange act of 1934 (amendment no.

March 13, 2023 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Jounce Therapeutics, Inc.

March 13, 2023 S-8

As filed with the Securities and Exchange Commission on March 14, 2023

As filed with the Securities and Exchange Commission on March 14, 2023 Registration No.

March 13, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2023 JOUNCE THERAPEUTIC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2023 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commissio

March 10, 2023 EX-10.3

Form of Restricted Stock Unit Award Agreement Amendment under 2017 Stock Option and Incentive Plan (for employees)

Exhibit 10.3 Amendment to Restricted Stock Unit Award Agreement for Company Employees under the 2017 Plan This Amendment to the Restricted Stock Unit Award Agreement for Company Employees under Jounce Therapeutics, Inc. 2017 Stock Option and Incentive Plan (this “Amendment”) is made as of January 13, 2023 by Jounce Therapeutics, Inc. (the “Company”). Background A. The Grantee has been awarded Rest

March 10, 2023 EX-21.1

List of Subsidiaries of the Registrant

Exhibit 21.1 Subsidiaries of the Registrant Name Jurisdiction of Organization Percentage Ownership Jounce Mass Securities, Inc. Massachusetts 100%

March 10, 2023 EX-10.23

First Amendment to Lease Agreement by and between ARE-770/784/790 Memorial Drive, LLC and the Registrant, dated March 21, 2017

Exhibit 10.23 FIRST AMENDMENT TO LEASE THIS FIRST AMENDMENT TO LEASE (this "First Amendment") is made as of March 21, 2017, by and between ARE-770/784/790 MEMORIAL DRIVE, LLC, a Delaware limited liability company ("Landlord"), and JOUNCE THERAPEUTICS, INC., a Delaware corporation ("Tenant"). RECITALS A. Landlord and Tenant are now parties to that certain Lease Agreement dated as of November 1, 201

March 10, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE THERAP

March 10, 2023 EX-10.4

Form of Non-Qualified Stock Option Agreement Inducement Grant for Employees, as amended

Exhibit 10.4 NON-QUALIFIED STOCK OPTION AGREEMENT INDUCEMENT GRANT FOR COMPANY EMPLOYEES FOR JOUNCE THERAPEUTICS, INC. Name of Optionee: No. of Option Shares: Option Exercise Price per Share: $ Vesting Commencement Date: Grant Date: Expiration Date: Jounce Therapeutics, Inc. (the “Company”) hereby grants to the Optionee named above an option (the “Stock Option” or the “Award”) to purchase on or pr

March 6, 2023 EX-99.1

JOINT FILING AGREEMENT

Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1) promulgated under the Securities Exchange Act of 1934, the undersigned agree to the joint filing of a Statement on Schedule 13G (including any and all amendments thereto) with respect to the Common Stock, $0.001 par value per share, of Jounce Therapeutics, Inc. and further agree to the filing of this agreement as an exhibit th

March 6, 2023 SC 13G

JNCE / Jounce Therapeutics Inc / TANG CAPITAL PARTNERS LP Passive Investment

Securities and Exchange Commission Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

February 23, 2023 EX-10.5

Consulting Agreement, by and between the Company and Hugh Cole, dated as of February 22, 2023

Exhibit 10.5 CONSULTING AGREEMENT THIS CONSULTING AGREEMENT (“Agreement”) is entered into as of February 22, 2023 and shall be effective at the close of business on the day that the Consultant’s employment with Jounce as a full-time, at-will employee terminates (such date, the “Effective Date”), by and between Hugh Cole, an individual residing at [***] (hereinafter “Consultant”) and Jounce Therape

February 23, 2023 EX-99.6

VOTING AND SUPPORT AGREEMENT

Exhibit 99.6 Execution Version VOTING AND SUPPORT AGREEMENT This VOTING AND SUPPORT AGREEMENT (this “Agreement”), dated as of February , 2023, is entered into by and among Redx Pharma plc, a publicly listed company organized in the United Kingdom (“Target”), Jounce Therapeutics, Inc., a Delaware corporation (“Parent”) and one or more persons set forth on Schedule A hereto (each, a “Stockholder” an

February 23, 2023 EX-2.1

Rule 2.7 Announcement

Exhibit 2.1 NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN OR INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OR REGULATIONS OF SUCH JURISDICTION. THIS ANNOUNCEMENT IS NOT A U.S. PROXY STATEMENT AND INVESTORS SHOULD NOT MAKE ANY INVESTMENT DECISION IN RELATION TO THE EXISTING JOUNCE SHARES OR NEW SHARES E

February 23, 2023 EX-10.6

Consulting Agreement, by and between the Company and Richard Murray, Ph.D., dated as of February 22, 2023

Exhibit 10.6 CONSULTING AGREEMENT THIS CONSULTING AGREEMENT (“Agreement”) is entered into as of February 22, 2023 and shall be effective at the close of business on the day that the Consultant’s employment with Jounce as a full-time, at-will employee terminates (such date, the “Effective Date”), by and between Richard Murray, Ph.D., an individual residing at [***] (hereinafter “Consultant”) and Jo

February 23, 2023 EX-2.2

Cooperation Agreement

exhibit22cooperationagre Exhibit 2.2 (1) JOUNCE THERAPEUTICS, INC. (2) REDX PHARMA PLC CO-OPERATION AGREEMENT COOLEY (UK) LLP, 22 BISHOPSGATE, LONDON EC2N 4BQ, UK T: +44 (0) 20 7583 4055 F: +44 (0) 20 7785 9355 WWW.COOLEY.COM CONTENTS Clause Page 1. Definitions and interpretation .................................................................................................... 1 2. Publication o

February 23, 2023 EX-99.6

Form of Voting and Support Agreement

Exhibit 99.6 Execution Version VOTING AND SUPPORT AGREEMENT This VOTING AND SUPPORT AGREEMENT (this “Agreement”), dated as of February , 2023, is entered into by and among Redx Pharma plc, a publicly listed company organized in the United Kingdom (“Target”), Jounce Therapeutics, Inc., a Delaware corporation (“Parent”) and one or more persons set forth on Schedule A hereto (each, a “Stockholder” an

February 23, 2023 EX-2.2

Cooperation Agreement

exhibit22cooperationagre Exhibit 2.2 (1) JOUNCE THERAPEUTICS, INC. (2) REDX PHARMA PLC CO-OPERATION AGREEMENT COOLEY (UK) LLP, 22 BISHOPSGATE, LONDON EC2N 4BQ, UK T: +44 (0) 20 7583 4055 F: +44 (0) 20 7785 9355 WWW.COOLEY.COM CONTENTS Clause Page 1. Definitions and interpretation .................................................................................................... 1 2. Publication o

February 23, 2023 EX-10.5

Consulting Agreement, by and between the Company and Hugh Cole, dated as of February 22, 2023

Exhibit 10.5 CONSULTING AGREEMENT THIS CONSULTING AGREEMENT (“Agreement”) is entered into as of February 22, 2023 and shall be effective at the close of business on the day that the Consultant’s employment with Jounce as a full-time, at-will employee terminates (such date, the “Effective Date”), by and between Hugh Cole, an individual residing at [***] (hereinafter “Consultant”) and Jounce Therape

February 23, 2023 EX-10.1

Amendment No. 1 to the Amended and Restated Employment Agreement, by and between the Company and Hugh Cole, dated as of January 27, 2023 (incorporated by reference to Exhibit 10.1 of the Registrant’s Current Report on Form 8-K (File No. 001-37998) filed February 23, 2023)

Exhibit 10.1 Amendment No. 1 to Employment Agreement This Amendment No. 1 to the Employment Agreement (this “Amendment No. 1), effective January 27, 2023 (the “Amendment No. 1 Effective Date”), is made and entered into by and between Jounce Therapeutics, Inc., a Delaware corporation (“Jounce”), and Hugh Cole (the “Executive”). Background A. Jounce and the Executive are parties to that certain Empl

February 23, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2023 JOUNCE THERAPEU

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2023 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commis

February 23, 2023 EX-99.8

Press Release of the Company, dated February 22, 2023

Exhibit 99.8 Jounce Therapeutics Announces Restructuring CAMBRIDGE, Mass., February 22, 2023 – Jounce Therapeutics, Inc. (Nasdaq: JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, announced today that it is reducing its workforce by approximately 57 percent. The decision to reduce its workforce was made as Jounce bel

February 23, 2023 EX-99.7

Redx and Jounce Announce Recommended Business Combination Combined group will have a strong clinical pipeline and proven expertise in the discovery and development of highly selective therapeutics for the treatment of cancer and fibrotic disease RXC0

Exhibit 99.7 Redx and Jounce Announce Recommended Business Combination Combined group will have a strong clinical pipeline and proven expertise in the discovery and development of highly selective therapeutics for the treatment of cancer and fibrotic disease RXC007, a next-generation selective ROCK2 inhibitor, to lead clinical pipeline; portfolio to include discovery projects from both Redx and Jo

February 23, 2023 EX-99.5

Form of Deed of Irrevocable Undertaking given by Redx Directors

Exhibit 99.5 Execution version DIRECTOR’S IRREVOCABLE UNDERTAKING To: Jounce Therapeutics, Inc. (the "Offeror") 780 Memorial Drive Cambridge Massachusetts, 2139 United States From: [Director] [Address] 2023 To whom it may concern, Proposed acquisition of and merger with Redx Pharma PLC ("Target") – Deed of Irrevocable Undertaking 1.I understand that the Offeror (on behalf of it and its affiliates,

February 23, 2023 EX-10.2

Amendment No. 1 to the Amended and Restated Employment Agreement, by and between the Company and Kim C. Drapkin, dated as of January 27, 2023

Exhibit 10.2 Amendment No. 1 to Amended and Restated Employment Agreement This Amendment No. 1 to the Amended and Restated Employment Agreement (this “Amendment No. 1”), effective January 27, 2023 (the “Amendment No. 1 Effective Date”), is made and entered into by and between Jounce Therapeutics, Inc., a Delaware corporation (“Jounce”), and Kim C. Drapkin (the “Executive”). Background A. Jounce an

February 23, 2023 EX-10.4

Amendment No. 1 to the Amended and Restated Employment Agreement, by and between the Company and Elizabeth Trehu, M.D., dated as of January 27, 2023

Exhibit 10.4 Amendment No. 1 to Amended and Restated Employment Agreement This Amendment No. 1 to the Amended and Restated Employment Agreement (this “Amendment No. 1”), effective January 27, 2023 (the “Amendment No. 1 Effective Date”), is made and entered into by and between Jounce Therapeutics, Inc., a Delaware corporation (“Jounce”), and Elizabeth Trehu, M.D. (the “Executive”). Background A. Jo

February 23, 2023 EX-2.3

Merger Agreement

Exhibit 2.3 AGREEMENT AND PLAN OF MERGER by and among JOUNCE THERAPEUTICS, INC., EVERGREEN MERGER SUB 1, LLC, and RM SPECIAL HOLDINGS 3, LLC Dated as of February 23, 2023 TABLE OF CONTENTS Page ARTICLE I The Mergers 5 SECTION 1.01. The Mergers 5 SECTION 1.02. Closing 5 SECTION 1.03. Effective Time 6 SECTION 1.04. Effects 6 SECTION 1.05. Organizational Documents. 6 SECTION 1.06. Officers 7 ARTICLE

February 23, 2023 EX-99.2

Deed of Irrevocable Undertaking, by and between the Company and Redx Supporting Shareholder 2, dated as of February 23, 2023

Exhibit 99.2 EXECUTION VERSION SHAREHOLDER'S IRREVOCABLE UNDERTAKING To: Jounce Therapeutics, Inc. (the "Offeror") 780 Memorial Drive, Cambridge Massachusetts, 02139 United States From: Supporting Shareholder [***] 23 February 2023 To whom it may concern, Proposed acquisition of and merger with Redx Pharma Plc ("Target") – Deed of Irrevocable Undertaking 1.We understand that the Offeror (on behalf

February 23, 2023 EX-99.3

SHAREHOLDER'S IRREVOCABLE UNDERTAKING

Exhibit 99.3 Execution Version SHAREHOLDER'S IRREVOCABLE UNDERTAKING To: Jounce Therapeutics, Inc. (the "Offeror") 780 Memorial Drive, Cambridge Massachusetts, 02139 United States From: Supporting Shareolder [***] 23 February 2023 To whom it may concern, Proposed acquisition of and merger with Redx Pharma Plc ("Target") – Deed of Irrevocable Undertaking 1.We understand that the Offeror (on behalf

February 23, 2023 EX-99.5

DIRECTOR’S IRREVOCABLE UNDERTAKING

Exhibit 99.5 Execution version DIRECTOR’S IRREVOCABLE UNDERTAKING To: Jounce Therapeutics, Inc. (the "Offeror") 780 Memorial Drive Cambridge Massachusetts, 2139 United States From: [Director] [Address] 2023 To whom it may concern, Proposed acquisition of and merger with Redx Pharma PLC ("Target") – Deed of Irrevocable Undertaking 1.I understand that the Offeror (on behalf of it and its affiliates,

February 23, 2023 EX-99.8

Jounce Therapeutics Announces Restructuring

Exhibit 99.8 Jounce Therapeutics Announces Restructuring CAMBRIDGE, Mass., February 22, 2023 – Jounce Therapeutics, Inc. (Nasdaq: JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, announced today that it is reducing its workforce by approximately 57 percent. The decision to reduce its workforce was made as Jounce bel

February 23, 2023 EX-99.1

SHAREHOLDER'S IRREVOCABLE UNDERTAKING

Exhibit 99.1 EXECUTION VERSION SHAREHOLDER'S IRREVOCABLE UNDERTAKING To: Jounce Therapeutics, Inc. (the "Offeror") 780 Memorial Drive, Cambridge Massachusetts, 02139 United States From: Supporting Shareholder 23 February 2023 To whom it may concern, Proposed acquisition of and merger with Redx Pharma Plc ("Target") – Deed of Irrevocable Undertaking 1.We understand that the Offeror (on behalf of it

February 23, 2023 EX-10.3

Amendment No. 1 to the Amended and Restated Employment Agreement, by and between the Company and Richard Murray, Ph.D., dated as of January 27, 2023

Exhibit 10.3 Amendment No. 1 to Amended and Restated Employment Agreement This Amendment No. 1 to the Amended and Restated Employment Agreement (this “Amendment No. 1”), effective January 27, 2023 (the “Amendment No. 1 Effective Date”), is made and entered into by and between Jounce Therapeutics, Inc., a Delaware corporation (“Jounce”), and Richard Murray, Ph.D. (the “Executive”). Background A. Jo

February 23, 2023 EX-10.3

Amendment No. 1 to the Amended and Restated Employment Agreement, by and between the Company and Richard Murray, Ph.D., dated as of January 27, 2023

Exhibit 10.3 Amendment No. 1 to Amended and Restated Employment Agreement This Amendment No. 1 to the Amended and Restated Employment Agreement (this “Amendment No. 1”), effective January 27, 2023 (the “Amendment No. 1 Effective Date”), is made and entered into by and between Jounce Therapeutics, Inc., a Delaware corporation (“Jounce”), and Richard Murray, Ph.D. (the “Executive”). Background A. Jo

February 23, 2023 EX-10.2

Amendment No. 1 to the Amended and Restated Employment Agreement, by and between the Company and Kim C. Drapkin, dated as of January 27, 2023

Exhibit 10.2 Amendment No. 1 to Amended and Restated Employment Agreement This Amendment No. 1 to the Amended and Restated Employment Agreement (this “Amendment No. 1”), effective January 27, 2023 (the “Amendment No. 1 Effective Date”), is made and entered into by and between Jounce Therapeutics, Inc., a Delaware corporation (“Jounce”), and Kim C. Drapkin (the “Executive”). Background A. Jounce an

February 23, 2023 EX-10.7

Consulting Agreement, by and between the Company and Elizabeth Trehu, M.D., dated as of February 22, 2023

Exhibit 10.7 CONSULTING AGREEMENT THIS CONSULTING AGREEMENT (“Agreement”) is entered into as of February 22, 2023 and shall be effective at the close of business on the day that the Consultant’s employment with Jounce as a full-time, at-will employee terminates (such date, the “Effective Date”), by and between Elizabeth Trehu, M.D., an individual with an address of [***] (hereinafter “Consultant”)

February 23, 2023 EX-99.1

Deed of Irrevocable Undertaking, by and between the Company and Redx Supporting Shareholder 1, dated as of February 23, 2023

Exhibit 99.1 EXECUTION VERSION SHAREHOLDER'S IRREVOCABLE UNDERTAKING To: Jounce Therapeutics, Inc. (the "Offeror") 780 Memorial Drive, Cambridge Massachusetts, 02139 United States From: Supporting Shareholder 23 February 2023 To whom it may concern, Proposed acquisition of and merger with Redx Pharma Plc ("Target") – Deed of Irrevocable Undertaking 1.We understand that the Offeror (on behalf of it

February 23, 2023 EX-99.4

Deed of Irrevocable Undertaking, by and between the Company and Redx Supporting Shareholder 4, dated as of February 23, 2023

Exhibit 99.4 Execution Version SHAREHOLDER'S IRREVOCABLE UNDERTAKING To: Jounce Therapeutics, Inc. (the "Offeror") 780 Memorial Drive, Cambridge Massachusetts, 02139 United States From: [***] (“Supporting Shareholder”) [***] 23 February 2023 To whom it may concern, Proposed acquisition of and merger with Redx Pharma Plc ("Target") – Deed of Irrevocable Undertaking 1.We understand that the Offeror

February 23, 2023 EX-2.3

Merger Agreement

Exhibit 2.3 AGREEMENT AND PLAN OF MERGER by and among JOUNCE THERAPEUTICS, INC., EVERGREEN MERGER SUB 1, LLC, and RM SPECIAL HOLDINGS 3, LLC Dated as of February 23, 2023 TABLE OF CONTENTS Page ARTICLE I The Mergers 5 SECTION 1.01. The Mergers 5 SECTION 1.02. Closing 5 SECTION 1.03. Effective Time 6 SECTION 1.04. Effects 6 SECTION 1.05. Organizational Documents. 6 SECTION 1.06. Officers 7 ARTICLE

February 23, 2023 EX-10.4

Amendment No. 1 to the Amended and Restated Employment Agreement, by and between the Company and Elizabeth Trehu, M.D., dated as of January 27, 2023

Exhibit 10.4 Amendment No. 1 to Amended and Restated Employment Agreement This Amendment No. 1 to the Amended and Restated Employment Agreement (this “Amendment No. 1”), effective January 27, 2023 (the “Amendment No. 1 Effective Date”), is made and entered into by and between Jounce Therapeutics, Inc., a Delaware corporation (“Jounce”), and Elizabeth Trehu, M.D. (the “Executive”). Background A. Jo

February 23, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2023 JOUNCE THERAPEU

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2023 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commis

February 23, 2023 EX-10.6

Consulting Agreement, by and between the Company and Richard Murray, Ph.D., dated as of February 22, 2023

Exhibit 10.6 CONSULTING AGREEMENT THIS CONSULTING AGREEMENT (“Agreement”) is entered into as of February 22, 2023 and shall be effective at the close of business on the day that the Consultant’s employment with Jounce as a full-time, at-will employee terminates (such date, the “Effective Date”), by and between Richard Murray, Ph.D., an individual residing at [***] (hereinafter “Consultant”) and Jo

February 23, 2023 EX-10.7

Consulting Agreement, by and between the Company and Elizabeth Trehu, M.D., dated as of February 22, 2023

Exhibit 10.7 CONSULTING AGREEMENT THIS CONSULTING AGREEMENT (“Agreement”) is entered into as of February 22, 2023 and shall be effective at the close of business on the day that the Consultant’s employment with Jounce as a full-time, at-will employee terminates (such date, the “Effective Date”), by and between Elizabeth Trehu, M.D., an individual with an address of [***] (hereinafter “Consultant”)

February 23, 2023 EX-99.3

Deed of Irrevocable Undertaking, by and between the Company and Redx Supporting Shareholder 3, dated as of February 23, 2023

Exhibit 99.3 Execution Version SHAREHOLDER'S IRREVOCABLE UNDERTAKING To: Jounce Therapeutics, Inc. (the "Offeror") 780 Memorial Drive, Cambridge Massachusetts, 02139 United States From: Supporting Shareolder [***] 23 February 2023 To whom it may concern, Proposed acquisition of and merger with Redx Pharma Plc ("Target") – Deed of Irrevocable Undertaking 1.We understand that the Offeror (on behalf

February 23, 2023 EX-99.4

SHAREHOLDER'S IRREVOCABLE UNDERTAKING

Exhibit 99.4 Execution Version SHAREHOLDER'S IRREVOCABLE UNDERTAKING To: Jounce Therapeutics, Inc. (the "Offeror") 780 Memorial Drive, Cambridge Massachusetts, 02139 United States From: [***] (“Supporting Shareholder”) [***] 23 February 2023 To whom it may concern, Proposed acquisition of and merger with Redx Pharma Plc ("Target") – Deed of Irrevocable Undertaking 1.We understand that the Offeror

February 23, 2023 EX-99.7

Joint Press Release of the Company and Redx, dated February 23, 2023

Exhibit 99.7 Redx and Jounce Announce Recommended Business Combination Combined group will have a strong clinical pipeline and proven expertise in the discovery and development of highly selective therapeutics for the treatment of cancer and fibrotic disease RXC007, a next-generation selective ROCK2 inhibitor, to lead clinical pipeline; portfolio to include discovery projects from both Redx and Jo

February 23, 2023 EX-99.2

SHAREHOLDER'S IRREVOCABLE UNDERTAKING

Exhibit 99.2 EXECUTION VERSION SHAREHOLDER'S IRREVOCABLE UNDERTAKING To: Jounce Therapeutics, Inc. (the "Offeror") 780 Memorial Drive, Cambridge Massachusetts, 02139 United States From: Supporting Shareholder [***] 23 February 2023 To whom it may concern, Proposed acquisition of and merger with Redx Pharma Plc ("Target") – Deed of Irrevocable Undertaking 1.We understand that the Offeror (on behalf

February 23, 2023 EX-2.1

Rule 2.7 Announcement

Exhibit 2.1 NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN OR INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OR REGULATIONS OF SUCH JURISDICTION. THIS ANNOUNCEMENT IS NOT A U.S. PROXY STATEMENT AND INVESTORS SHOULD NOT MAKE ANY INVESTMENT DECISION IN RELATION TO THE EXISTING JOUNCE SHARES OR NEW SHARES E

February 23, 2023 EX-10.1

Amendment No. 1 to the Employment Agreement, by and between the Company and Hugh Cole, dated as of January 27, 2023

Exhibit 10.1 Amendment No. 1 to Employment Agreement This Amendment No. 1 to the Employment Agreement (this “Amendment No. 1), effective January 27, 2023 (the “Amendment No. 1 Effective Date”), is made and entered into by and between Jounce Therapeutics, Inc., a Delaware corporation (“Jounce”), and Hugh Cole (the “Executive”). Background A. Jounce and the Executive are parties to that certain Empl

February 14, 2023 SC 13G

JNCE / Jounce Therapeutics Inc / BANK OF AMERICA CORP /DE/ Passive Investment

SC 13G 1 doc1.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. N/A)* Jounce Therapeutics Inc (Name of Issuer) Common Stock (Title of Class of Securities) 4811161011 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule p

February 14, 2023 EX-99

BANK OF AMERICA CORPORATION LIMITED POWER OF ATTORNEY BANK OF AMERICA CORPORATION

EX-99 2 boa-poa2.htm BANK OF AMERICA CORPORATION LIMITED POWER OF ATTORNEY BANK OF AMERICA CORPORATION, a Delaware corporation (the "Corporation"), does hereby make, constitute, and appoint each of Kelvin Kwok, Tolu Tade, Andres Ortiz Custodio, Frank Lui, James Todd, Zainab Tarteel, Hannah Chae and Monica Yako as an attorney-in-fact for the Corporation acting for the Corporation and in the Corpora

February 14, 2023 EX-99

JOINT FILING AGREEMENT

EX-99 2 ss1758581ex99a.htm JOINT FILING AGREEMENT EXHIBIT A JOINT FILING AGREEMENT The undersigned hereby agree that the Statement on this Schedule 13G dated December 31, 2022 (the “Schedule 13G”), with respect to the Common Stock, $0.001 par value per share, of Jounce Therapeutics, Inc. is filed on behalf of each of us pursuant to and in accordance with the provisions of Rule 13d-1(k) under the S

February 14, 2023 SC 13G/A

JNCE / Jounce Therapeutics Inc / Deep Track Capital, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No.

February 14, 2023 SC 13G/A

JNCE / Jounce Therapeutics Inc / ORBIMED ADVISORS LLC - AMENDMENT NO. 1 Passive Investment

SC 13G/A 1 ss1758581sc13g.htm AMENDMENT NO. 1 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Amendment No. 1)* Under the Securities Exchange Act of 1934 Jounce Therapeutics, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 481116101 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Stateme

February 14, 2023 SC 13G/A

JNCE / Jounce Therapeutics Inc / Third Rock Ventures II, L.P. - SC 13G/A Passive Investment

SC 13G/A 1 d257659dsc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 3 )* Jounce Therapeutics, Inc. (Name of Issuer) COMMON STOCK, $0.001 PAR VALUE PER SHARE (Title of Class of Securities) 481116101 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Statement)

February 14, 2023 SC 13G/A

JNCE / Jounce Therapeutics Inc / PFM Health Sciences, LP - SC 13G/A Passive Investment

February 14, 2023 SC 13G/A

JNCE / Jounce Therapeutics Inc / RTW INVESTMENTS, LP - JOUNCE THERAPEUTICS, INC. Passive Investment

SC 13G/A 1 p23-0489sc13ga.htm JOUNCE THERAPEUTICS, INC. SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Jounce Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 481116101 (CUSIP Number) December 31, 2022 (Date of event which requires filing of this stateme

January 23, 2023 SC 13G/A

JNCE / Jounce Therapeutics Inc / Cowen Financial Products LLC - COWEN FINANCIAL PRODUCTS LLC Passive Investment

SC 13G/A 1 jncea112323.htm COWEN FINANCIAL PRODUCTS LLC UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Jounce Therapeutics Inc. (Name of Issuer) common stock (Title of Class of Securities) 481116101 (CUSIP Number) December 30, 2022 (Date of Event which Requires Filing of this Statement) Check the app

January 20, 2023 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2023 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commiss

January 5, 2023 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 29, 2022 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commis

December 27, 2022 EX-99.1

GILEAD TO ACQUIRE ALL REMAINING RIGHTS TO POTENTIAL FIRST-IN-CLASS IMMUNOTHERAPY GS-1811 FROM JOUNCE THERAPEUTICS -- Agreement Covers Buyout of Remaining Financial Obligations for Anti-CCR8 Antibody in Development as a Potential Treatment for Solid T

Exhibit 99.1 Gilead Contacts: Jacquie Ross, Investors [email protected] Meaghan Smith, Media [email protected] Jounce Contact: Eric Laub, Media and Investors [email protected], (857) 259-3853 GILEAD TO ACQUIRE ALL REMAINING RIGHTS TO POTENTIAL FIRST-IN-CLASS IMMUNOTHERAPY GS-1811 FROM JOUNCE THERAPEUTICS - Agreement Covers Buyout of Remaining Financial Obligations for Anti-CCR8

December 27, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 27, 2022 JOUNCE THERAPEU

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 27, 2022 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commis

December 27, 2022 EX-10.1

Asset Purchase and License Amendment Agreement by and between the Company and Gilead dated December 27, 2022

Exhibit 10.1 CERTAIN CONFIDENTIAL PORTIONS OF THIS EXHIBIT HAVE BEEN OMITTED AND REPLACED WITH “[***]”. SUCH IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS (I) NOT MATERIAL AND (II) WOULD LIKELY CAUSE COMPETITIVE HARM TO THE COMPANY IF DISCLOSED. ASSET PURCHASE AND LICENSE AMENDMENT AGREEMENT This Asset Purchase and License Amendment Agreement (this “Agreement”), dated as

December 20, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 16, 2022 JOUNCE THERAPEU

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 16, 2022 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commis

November 10, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE

November 10, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2022 JOUNCE THERAPEU

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2022 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commis

November 10, 2022 EX-99.1

Jounce Therapeutics Reports Third Quarter 2022 Financial Results - INNATE trial of JTX-8064 +/- pimivalimab Phase 1 Dose Escalation data at ESMO-IO Annual Congress - - SELECT randomized trial of pimivalimab +/- vopratelimab phase 2 data at ESMO-IO An

Exhibit 99.1 Jounce Therapeutics Reports Third Quarter 2022 Financial Results - INNATE trial of JTX-8064 +/- pimivalimab Phase 1 Dose Escalation data at ESMO-IO Annual Congress - - SELECT randomized trial of pimivalimab +/- vopratelimab phase 2 data at ESMO-IO Annual Congress - - Two preclinical posters on JTX-1484 and LILRB family at SITC 2022 - - Ended the quarter with $130.3 million in cash, ca

August 30, 2022 EX-99.2

Jounce Therapeutics Reports Results from Phase 2 Randomized SELECT Trial Testing 2 Different Doses of Vopratelimab in TISvopra Biomarker-Selected Patients - SELECT trial of vopratelimab in combination with pimivalimab versus pimivalimab alone did not

Exhibit 99.2 Jounce Therapeutics Reports Results from Phase 2 Randomized SELECT Trial Testing 2 Different Doses of Vopratelimab in TISvopra Biomarker-Selected Patients - SELECT trial of vopratelimab in combination with pimivalimab versus pimivalimab alone did not meet its primary endpoint of mean tumor change averaged over 9 and 18 weeks - - Encouraging trends in improved mean tumor change over 9

August 30, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 30, 2022 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commissi

August 30, 2022 EX-99.1

Jounce Therapeutics Corporate Presentation A NEXT GEN IMMUNOTHERAPY COMPANY AUGUST 2022 Exhib i t 99.1 Legal Disclaimer 2 Various statements concerning our future expectations, plans and prospects, including without limitation, our expectations regar

Jounce Therapeutics Corporate Presentation A NEXT GEN IMMUNOTHERAPY COMPANY AUGUST 2022 Exhib i t 99.

August 4, 2022 EX-99.1

Jounce Therapeutics Reports Second Quarter 2022 Financial Results - INNATE trial of JTX-8064 +/- pimivalimab on track to present preliminary data on at least 80 Phase 2 patients across multiple cohorts by year end - - Patient enrollment complete in t

Exhibit 99.1 Jounce Therapeutics Reports Second Quarter 2022 Financial Results - INNATE trial of JTX-8064 +/- pimivalimab on track to present preliminary data on at least 80 Phase 2 patients across multiple cohorts by year end - - Patient enrollment complete in the randomized, Phase 2 SELECT trial of vopratelimab in combination with pimivalimab; Data to be reported by year end - - Submitted two ab

August 4, 2022 EX-10.1

Amended and Restated Non-Employee Director Compensation Policy

Exhibit 10.1 Jounce Therapeutics, Inc. Amended and Restated Non-Employee Director Compensation Policy The purpose of this Non-Employee Director Compensation Policy (the ?Policy?) of Jounce Therapeutics, Inc., a Delaware corporation (the ?Company?), is to provide a total compensation package that enables the Company to attract and retain, on a long-term basis, high-caliber directors who are not emp

August 4, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 4, 2022 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commissio

August 4, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE THERA

June 27, 2022 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 24, 2022 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission

May 5, 2022 EX-99.1

Jounce Therapeutics Reports First Quarter 2022 Financial Results - Two combination cohorts met initial response criteria for continued expansion in INNATE trial of JTX-8064; on track to present data on at least 60 Phase 2 patients across multiple coh

Exhibit 99.1 Jounce Therapeutics Reports First Quarter 2022 Financial Results - Two combination cohorts met initial response criteria for continued expansion in INNATE trial of JTX-8064; on track to present data on at least 60 Phase 2 patients across multiple cohorts in 2H2022 - - Target enrollment achieved in SELECT trial of vopratelimab in combination with pimivalimab; data expected in 2H2022 -

May 5, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE THER

May 5, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2022 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission F

April 28, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ý Filed by a party other than the Registran

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Defin

April 28, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ý Filed by a party other than the Registran

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

April 22, 2022 SC 13G

JNCE / Jounce Therapeutics Inc / Cowen Financial Products LLC - COWEN FINANCIAL PRODUCTS LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Jounce Therapeutics Inc. (Name of Issuer) common stock (Title of Class of Securities) 481116101 (CUSIP Number) April 21, 2022 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [

March 7, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 7, 2022 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission

March 7, 2022 EX-99.1

Jounce Therapeutics Corporate Presentation A NEXT GEN IMMUNOTHERAPY COMPANY MARCH 2022 Exhibit 99.1 Legal Disclaimer 2 Various statements concerning our future expectations, plans and prospects, including without limitation, our expectations regardin

Jounce Therapeutics Corporate Presentation A NEXT GEN IMMUNOTHERAPY COMPANY MARCH 2022 Exhibit 99.

March 2, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 2, 2022 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission

March 2, 2022 EX-21.1

List of Subsidiaries of the Registrant

Exhibit 21.1 Subsidiaries of the Registrant Name Jurisdiction of Organization Percentage Ownership Jounce Mass Securities, Inc. Massachusetts 100%

March 2, 2022 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Jounce Therapeutics, Inc.

March 2, 2022 S-8

As filed with the Securities and Exchange Commission on March 2, 2022

As filed with the Securities and Exchange Commission on March 2, 2022 Registration No.

March 2, 2022 EX-10.6

Amended and Restated Non-Employee Director Compensation Policy

Exhibit 10.6 Jounce Therapeutics, Inc. Amended and Restated Non-Employee Director Compensation Policy The purpose of this Non-Employee Director Compensation Policy (the ?Policy?) of Jounce Therapeutics, Inc., a Delaware corporation (the ?Company?), is to provide a total compensation package that enables the Company to attract and retain, on a long-term basis, high-caliber directors who are not emp

March 2, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE THERAP

March 2, 2022 EX-99.1

Jounce Therapeutics Reports Fourth Quarter and Full Year 2021 Financial Results - Continued execution on two proof-of-concept clinical trials for JTX-8064 and Vopratelimab, INNATE and SELECT, with clinical data on track for 2022 - - JTX-1484, a new a

Exhibit 99.1 Jounce Therapeutics Reports Fourth Quarter and Full Year 2021 Financial Results - Continued execution on two proof-of-concept clinical trials for JTX-8064 and Vopratelimab, INNATE and SELECT, with clinical data on track for 2022 - - JTX-1484, a new antagonist antibody targeting LILRB4, enters IND-enabling activities representing the fifth internally discovered development program - -

February 14, 2022 SC 13G/A

JNCE / Jounce Therapeutics Inc / Deep Track Capital, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No.

February 14, 2022 EX-99.1

Joint Filing Agreement

EXHIBIT 99.1 Joint Filing Agreement The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing statements. The undersigned acknowledge that each shall be

February 14, 2022 SC 13G

JNCE / Jounce Therapeutics Inc / RTW INVESTMENTS, LP - JOUNCE THERAPEUTICS, INC. Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Jounce Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 481116101 (CUSIP Number) December 31, 2021 (Date of event which requires filing of this statement) Check the appropriate box to designate the rule pursuan

February 14, 2022 EX-99.1

JOINT FILING AGREEMENT

EXHIBIT 99.1 JOINT FILING AGREEMENT The undersigned hereby agree that the Statement on Schedule 13G/A filed herewith (and any amendments thereto), relating to the common stock of Jounce Therapeutics, Inc., a Delaware corporation, is being filed jointly with the Securities and Exchange Commission pursuant to Rule 13d-1(c) under the Securities Exchange Act of 1934, as amended, on behalf of each of t

February 14, 2022 SC 13G/A

JNCE / Jounce Therapeutics Inc / Third Rock Ventures II, L.P. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 2 )* Jounce Therapeutics, Inc. (Name of Issuer) COMMON STOCK, $0.001 PAR VALUE PER SHARE (Title of Class of Securities) 481116101 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate

February 14, 2022 SC 13G/A

JNCE / Jounce Therapeutics Inc / PFM Health Sciences, LP - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) Information Statement Pursuant to Rules 13d-1 and 13d-2 Under the Securities Exchange Act of 1934 (Amendment No. 1 )* Jounce Therapeutics, Inc. (Name of Issuer) Common stock, $0.001 par value per share (Title of Class of Securities) 481116101 (CUSIP Number) December 31, 2021 Date of Event Which Requ

February 14, 2022 EX-99.24

POWER OF ATTORNEY

EXHIBIT 24 POWER OF ATTORNEY KNOW ALL MEN BY THESE PRESENTS, that the undersigned hereby constitutes and appoints Kevin Gillis his true and lawful attorney-in-fact, with full power of substitution, to sign any and all instruments, certificates and documents that may be necessary, desirable or appropriate to be executed on behalf of himself as an individual or in his capacity as a direct or indirec

February 11, 2022 SC 13G

JNCE / Jounce Therapeutics Inc / ORBIMED ADVISORS LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Jounce Therapeutics, Inc.

February 11, 2022 EX-99.A

JOINT FILING AGREEMENT

CUSIP No. 481116101 SCHEDULE 13G Page 8 of 8 Pages EXHIBIT A JOINT FILING AGREEMENT The undersigned hereby agree that the Statement on this Schedule 13G dated February 11, 2022 (the ?Schedule 13G?), with respect to the Common Stock, $0.001 par value per share, of Jounce Therapeutics, Inc. is filed on behalf of each of us pursuant to and in accordance with the provisions of Rule 13d-1(k) under the

February 10, 2022 SC 13G/A

JNCE / Jounce Therapeutics Inc / ADAGE CAPITAL PARTNERS GP, L.L.C. - JOUNCE THERAPEUTICS, INC. Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Jounce Therapeutics, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 481116101 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule purs

January 10, 2022 EX-99.1

Jounce Therapeutics Corporate Presentation A NEXT GEN IMMUNOTHERAPY COMPANY JANUARY 2022 Exhibit 99.1 Legal Disclaimer 2 Various statements concerning our future expectations, plans and prospects, including without limitation, our expectations regard

Jounce Therapeutics Corporate Presentation A NEXT GEN IMMUNOTHERAPY COMPANY JANUARY 2022 Exhibit 99.

January 10, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 10, 2022 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commiss

November 4, 2021 EX-99.1

Jounce Therapeutics Reports Third Quarter 2021 Financial Results - Commenced enrollment in tumor-specific monotherapy and pimivalimab combination expansion cohorts of INNATE trial of JTX-8064 - - Ended the quarter with $249.0 million in cash, cash eq

Exhibit 99.1 Jounce Therapeutics Reports Third Quarter 2021 Financial Results - Commenced enrollment in tumor-specific monotherapy and pimivalimab combination expansion cohorts of INNATE trial of JTX-8064 - - Ended the quarter with $249.0 million in cash, cash equivalents and investments - - Company to host conference call and webcast today at 8:00 AM ET - CAMBRIDGE, Mass., November 4, 2021 - Joun

November 4, 2021 424B5

PROSPECTUS SUPPLEMENT (To prospectus dated May 19, 2021) Jounce Therapeutics, Inc. Common Stock

Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-255760 PROSPECTUS SUPPLEMENT (To prospectus dated May 19, 2021) $75,000,000 Jounce Therapeutics, Inc. Common Stock We have entered into a sales agreement with Cowen and Company, LLC, or Cowen, relating to shares of our common stock offered by this prospectus supplement and the accompanying prospectus. In accordance with the te

November 4, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE

November 4, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 4, 2021 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commiss

November 4, 2021 EX-1.1

Sales Agreement, dated of November 4, 2021 by and between the Registrant and Cowen and Company, LLC (incorporated by reference to Exhibit 1.1 of the Registrant’s Current Report on Form 8-K (File No. 001-37998) filed November 4, 2021)

JOUNCE THERAPEUTICS, INC. $75,000,000 COMMON STOCK SALES AGREEMENT November 4, 2021 Cowen and Company, LLC 599 Lexington Avenue New York, NY 10022 Ladies and Gentlemen: Jounce Therapeutics, Inc. (the ?Company?), confirms its agreement (this ?Agreement?) with Cowen and Company, LLC (?Cowen?), as follows: 1. Issuance and Sale of Shares. The Company agrees that, from time to time during the term of t

November 4, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 4, 2021 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commiss

September 15, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 15, 2021 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commi

September 1, 2021 SC 13G

JNCE / Jounce Therapeutics Inc / Deep Track Capital, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

August 5, 2021 EX-10.1

Form of Non-Qualified Stock Option Agreement Inducement Grant for Employees (incorporated by reference to Exhibit 10.1 of the Registrant’s Quarterly Report on Form 10-Q (File No. 001-37998) filed August 5, 2021)

Exhibit 10.1 NON-QUALIFIED STOCK OPTION AGREEMENT INDUCEMENT GRANT FOR COMPANY EMPLOYEES FOR JOUNCE THERAPEUTICS, INC. Name of Optionee: No. of Option Shares: Option Exercise Price per Share: $ Vesting Commencement Date: Grant Date: Expiration Date: Jounce Therapeutics, Inc. (the ?Company?) hereby grants to the Optionee named above an option (the ?Stock Option? or the ?Award?) to purchase on or pr

August 5, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 5, 2021 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commissio

August 5, 2021 EX-99.1

Jounce Therapeutics Reports Second Quarter 2021 Financial Results - INNATE monotherapy dose escalation enrollment completed and target dose selected, on track to initiate indication specific expansions in third quarter 2021- - Announced two additiona

Exhibit 99.1 Jounce Therapeutics Reports Second Quarter 2021 Financial Results - INNATE monotherapy dose escalation enrollment completed and target dose selected, on track to initiate indication specific expansions in third quarter 2021- - Announced two additional LILRB family targets as potential future development candidates - - Ended the quarter with $246.1 million in cash, cash equivalents and

August 5, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE THERA

June 23, 2021 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 18, 2021 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission

May 17, 2021 CORRESP

JOUNCE THERAPEUTICS, INC. 780 Memorial Drive Cambridge, MA 02139

JOUNCE THERAPEUTICS, INC. 780 Memorial Drive Cambridge, MA 02139 May 17, 2021 VIA EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Jounce Therapeutics, Inc. Registration Statement on Form S-3 File No. 333-255760 Request for Acceleration Ladies and Gentlemen: Pursuant to Rule 461 promulgated under the Securities Act of 1933, as a

May 4, 2021 EX-4.8

Form of Senior Note

Exhibit 4.8 Form of Senior Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE OF THE

May 4, 2021 S-3

- S-3

As filed with the Securities and Exchange Commission on May 4, 2021 Registration No.

May 4, 2021 EX-4.7

Form of Subordinated Indenture

Exhibit 4.7 JOUNCE THERAPEUTICS, INC. and Trustee INDENTURE Dated as of SUBORDINATED DEBT SECURITIES CROSS-REFERENCE TABLE 1 Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 314

May 4, 2021 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE THER

May 4, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 4, 2021 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission F

May 4, 2021 EX-4.6

Form of Senior Indenture

Exhibit 4.6 JOUNCE THERAPEUTICS, INC. and Trustee INDENTURE Dated as of SENIOR DEBT SECURITIES CROSS-REFERENCE TABLE1 Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 314(b) Ina

May 4, 2021 EX-99.1

Jounce Therapeutics Reports First Quarter 2021 Financial Results - Enrollment on track in both the Phase 1 INNATE trial of JTX-8064 (LILRB2 / ILT4) and the biomarker selected Phase 2 SELECT trial of Vopratelimab in combination with Pimivalimab - - En

Exhibit 99.1 Jounce Therapeutics Reports First Quarter 2021 Financial Results - Enrollment on track in both the Phase 1 INNATE trial of JTX-8064 (LILRB2 / ILT4) and the biomarker selected Phase 2 SELECT trial of Vopratelimab in combination with Pimivalimab - - Ended the quarter with $271.3 million in cash, cash equivalents and investments - - Company to host conference call and webcast today at 8:

May 4, 2021 EX-4.9

Form of Subordinated Note

Exhibit 4.9 Form of Subordinated Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE

April 26, 2021 DEF 14A

- DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

April 26, 2021 DEFA14A

- DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Defin

April 5, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Jounce Therapeutics, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Jounce Therapeutics, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 481116101 (CUSIP Number) November 20, 2019 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule pu

April 5, 2021 EX-99.1

Joint Filing Agreement

Exhibit 99.1 Joint Filing Agreement The persons below hereby agree that the Schedule 13G to which this agreement is attached as an exhibit, as well as all future amendments to such Schedule 13G, shall be filed jointly on behalf of each of them. This agreement is intended to satisfy the requirements of Rule 13d-1(k)(1)(iii) under the Securities Exchange Act of 1934. The undersigned also agree that

March 10, 2021 EX-99.1

Jounce Therapeutics Announces Proposed Offering of Common Stock

Exhibit 99.1 Jounce Therapeutics Announces Proposed Offering of Common Stock CAMBRIDGE, Mass., Mar. 9, 2021 – Jounce Therapeutics, Inc. (Nasdaq: JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today announced that it is offering to sell shares of its common stock in an underwritten public offering. The proceeds of

March 10, 2021 EX-1.1

Underwriting Agreement, dated March 9, 2021, by and among Jounce Therapeutics, Inc., Cowen and Company, LLC and Piper Sandler & Co., as representatives of the several underwriters identified therein

Exhibit 1.1 JOUNCE THERAPEUTICS, INC. 5,000,000 Shares of Common Stock, par value $0.001 per share Underwriting Agreement March 9, 2021 Cowen and Company, LLC Piper Sandler & Co. As Representatives of the several Underwriters listed in Schedule 1 hereto c/o Cowen and Company, LLC 559 Lexington Avenue New York, New York 10022 c/o Piper Sandler & Co. 800 Nicollet Mall, Suite 900 Minneapolis, MN 5540

March 10, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 9, 2021 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission

March 10, 2021 424B5

Prospectus supplement (to prospectus dated May 1, 2018) 5,000,000 shares Common Stock

Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-223518 Prospectus supplement (to prospectus dated May 1, 2018) 5,000,000 shares Common Stock We are offering 5,000,000 shares of our common stock Our common stock is quoted on the Nasdaq Global Select Market under the symbol ?JNCE?. On March 9, 2021, the last reported sale price of our common stock on the Nasdaq Global Select

March 10, 2021 EX-99.2

Jounce Therapeutics Announces Pricing of $56.25 Million Public Offering of Common Stock

Exhibit 99.2 Jounce Therapeutics Announces Pricing of $56.25 Million Public Offering of Common Stock CAMBRIDGE, Mass., Mar. 9, 2021 ? Jounce Therapeutics, Inc. (Nasdaq: JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today announced that it has priced an underwritten public offering of 5,000,000 shares of common st

March 9, 2021 424B5

Prospectus supplement (to prospectus dated May 1, 2018) Subject to completion, dated March 9, 2021 Common Stock

Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-223518 The information in this preliminary prospectus supplement is not complete and may be changed. This preliminary prospectus supplement is not an offer to sell these securities and we are not soliciting offers to buy these securities in any state or jurisdiction where the offer or sale is not permitted. Prospectus suppleme

February 25, 2021 EX-10.5

Amended and Restated Non-Employee Director Compensation Policy

Exhibit 10.5 Jounce Therapeutics, Inc. Amended and Restated Non-Employee Director Compensation Policy The purpose of this Non-Employee Director Compensation Policy (the ?Policy?) of Jounce Therapeutics, Inc., a Delaware corporation (the ?Company?), is to provide a total compensation package that enables the Company to attract and retain, on a long-term basis, high-caliber directors who are not emp

February 25, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 25, 2021 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commis

February 25, 2021 EX-21.1

List of Subsidiaries of the Registrant

EX-21.1 3 jnce12312020exhibit211.htm EX-21.1 Exhibit 21.1 Subsidiaries of the Registrant Name Jurisdiction of Organization Percentage Ownership Jounce Mass Securities, Inc. Massachusetts 100%

February 25, 2021 10-K

Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE THERAP

February 25, 2021 S-8

- S-8

As filed with the Securities and Exchange Commission on February 25, 2021 Registration No.

February 25, 2021 EX-99.1

Jounce Therapeutics Reports Fourth Quarter and Full Year 2020 Financial Results - Commenced enrollment in both the Phase 1 INNATE trial of JTX-8064 (LILRB2 / ILT4) and the Phase 2 SELECT trial of Vopratelimab in combination with JTX-4014 - - Ended 20

Exhibit 99.1 Jounce Therapeutics Reports Fourth Quarter and Full Year 2020 Financial Results - Commenced enrollment in both the Phase 1 INNATE trial of JTX-8064 (LILRB2 / ILT4) and the Phase 2 SELECT trial of Vopratelimab in combination with JTX-4014 - - Ended 2020 with $213.2 million in cash, cash equivalents and investments - - Company to host conference call and webcast today at 8:00 AM ET - CA

February 16, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1 )* Jounce Therapeutics, Inc. (Name of Issuer) COMMON STOCK, $0.001 PAR VALUE PER SHARE (Title of Class of

SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1 )* Jounce Therapeutics, Inc. (Name of Issuer) COMMON STOCK, $0.001 PAR VALUE PER SHARE (Title of Class of Securities) 481116101 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to d

February 12, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 10, 2021 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commis

February 1, 2021 SC 13G

January 20, 2021

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) Information Statement Pursuant to Rules 13d-1 and 13d-2 Under the Securities Exchange Act of 1934 (Amendment No. )* Jounce Therapeutics, Inc. (Name of Issuer) Common stock, $0.001 par value per share (Title of Class of Securities) 481116101 (CUSIP Number) January 20, 2021 Date of Event Which Require

February 1, 2021 EX-99.1

JOINT FILING AGREEMENT

EXHIBIT 99.1 JOINT FILING AGREEMENT The undersigned hereby agree that the Statement on Schedule 13G filed herewith (and any amendments thereto), relating to the common stock of Jounce Therapeutics, Inc., a Delaware corporation, is being filed jointly with the Securities and Exchange Commission pursuant to Rule 13d-1(c) under the Securities Exchange Act of 1934, as amended, on behalf of each of the

January 29, 2021 SC 13G

Jounce Therapeutics, Inc.

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Jounce Therapeutics, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 481116101 (CUSIP Number) January 19, 2021 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule pursuant

January 11, 2021 EX-99.1

Jounce Therapeutics A Next Gen Immunotherapy Company January 2021 Legal Disclaimer Various statements concerning our future expectations, plans and prospects, including without limitation, our expectations regarding the timing, progress and results o

jnce01112021exhibit991 Jounce Therapeutics A Next Gen Immunotherapy Company January 2021 Legal Disclaimer Various statements concerning our future expectations, plans and prospects, including without limitation, our expectations regarding the timing, progress and results of discovery programs, preclinical studies and clinical trials for our product candidates and any future product candidates, the

January 11, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 11, 2021 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commiss

November 6, 2020 EX-99.1

Jounce Therapeutics Reports Third Quarter 2020 Financial Results -On track to begin enrollment in the Phase 1 trial for JTX-8064 by year-end 2020- -Established exclusive license agreement with Gilead for JTX-1811- -Initiated the Phase 2 SELECT biomar

Exhibit 99.1 Jounce Therapeutics Reports Third Quarter 2020 Financial Results -On track to begin enrollment in the Phase 1 trial for JTX-8064 by year-end 2020- -Established exclusive license agreement with Gilead for JTX-1811- -Initiated the Phase 2 SELECT biomarker selection trial of vopratelimab in combination with JTX-4014- -Company to host conference call and webcast today at 8:00 AM ET- CAMBR

November 6, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2020 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE

November 6, 2020 EX-10.1

License Agreement by and between the Registrant and Gilead Sciences, Inc., dated August 31, 2020 (incorporated by reference to Exhibit 10.1 of the Registrant’s Quarterly Report on Form 10-Q (File No. 001-37998) filed on November 6, 2020)

Exhibit 10.1 CERTAIN CONFIDENTIAL PORTIONS OF THIS EXHIBIT HAVE BEEN OMITTED AND REPLACED WITH “[***]”. SUCH IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS (I) NOT MATERIAL AND (II) WOULD LIKELY CAUSE COMPETITIVE HARM TO THE COMPANY IF DISCLOSED. LICENSE AGREEMENT by and between JOUNCE THERAPEUTICS, INC. and GILEAD SCIENCES, INC. dated as of August 31, 2020 Table of Conte

November 6, 2020 EX-10.3

Registration Rights Agreement by and between the Registrant and Gilead Sciences, Inc., dated August 31, 2020 (incorporated by reference to Exhibit 10.3 of the Registrant’s Quarterly Report on Form 10-Q (File No. 001-37998) filed on November 6, 2020)

Exhibit 10.3 CERTAIN CONFIDENTIAL PORTIONS OF THIS EXHIBIT HAVE BEEN OMITTED AND REPLACED WITH “[***]”. SUCH IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS (I) NOT MATERIAL AND (II) WOULD LIKELY CAUSE COMPETITIVE HARM TO THE COMPANY IF DISCLOSED. REGISTRATION RIGHTS AGREEMENT THIS REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of August 31, 2020, is by and bet

November 6, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 6, 2020 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commiss

November 6, 2020 EX-10.2

Stock Purchase Agreement by and between the Registrant and Gilead Sciences, Inc., dated August 31, 2020 (incorporated by reference to Exhibit 10.2 of the Registrant’s Quarterly Report on Form 10-Q (File No. 001-37998) filed on November 6, 2020)

Exhibit 10.2 CERTAIN CONFIDENTIAL PORTIONS OF THIS EXHIBIT HAVE BEEN OMITTED AND REPLACED WITH “[***]”. SUCH IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS (I) NOT MATERIAL AND (II) WOULD LIKELY CAUSE COMPETITIVE HARM TO THE COMPANY IF DISCLOSED. STOCK PURCHASE AGREEMENT THIS STOCK PURCHASE AGREEMENT (this “Agreement”), dated as of August 31, 2020 (the “Execution Date”),

November 2, 2020 EX-99.1

Jounce Therapeutics Announces Update on Vopratelimab Program - No further enrollment in EMERGE trial of vopratelimab in combination with ipilimumab based on interim analysis- - First patient dosed in SELECT trial of vopratelimab in combination with J

Exhibit 99.1 Jounce Therapeutics Announces Update on Vopratelimab Program - No further enrollment in EMERGE trial of vopratelimab in combination with ipilimumab based on interim analysis- - First patient dosed in SELECT trial of vopratelimab in combination with JTX-4014 in immunotherapy naïve biomarker-selected NSCLC- -Company to host conference call and webcast today at 8:00AM ET- CAMBRIDGE, Mass

November 2, 2020 8-K

Financial Statements and Exhibits, Other Events - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 2, 2020 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commiss

October 26, 2020 SC 13G

JNCE / Jounce Therapeutics, Inc. / GILEAD SCIENCES INC - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Jounce Therapeutics, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 481116101 (CUSIP Number) October 16, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the

September 1, 2020 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 31, 2020 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commissi

September 1, 2020 EX-99.1

GILEAD SCIENCES AND JOUNCE THERAPEUTICS ANNOUNCE EXCLUSIVE LICENSE AGREEMENT FOR NOVEL IMMUNOTHERAPY PROGRAM – Gilead Will Have Exclusive Rights to Develop and Commercialize Anti-CCR8 Antibody – – Gilead to Make $85 Million Upfront Payment and $35 Mi

Exhibit 99.1 Gilead Contacts: Jounce Contact: Douglas Maffei, PhD, Investors Komal Joshi, Investors and Media (650) 522-2739 (857) 320-2523 Marni Kottle, Media (650) 522-5388 For Immediate Release GILEAD SCIENCES AND JOUNCE THERAPEUTICS ANNOUNCE EXCLUSIVE LICENSE AGREEMENT FOR NOVEL IMMUNOTHERAPY PROGRAM – Gilead Will Have Exclusive Rights to Develop and Commercialize Anti-CCR8 Antibody – – Gilead

August 7, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2020 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE THERA

August 7, 2020 EX-99.1

Jounce Therapeutics Reports Second Quarter 2020 Financial Results - Completed enrollment of Phase 2 EMERGE trial for the interim analysis of efficacy and biomarker data in early 2021 - - On track to initiate Phase 2 SELECT trial and Phase 1 trial for

Exhibit 99.1 Jounce Therapeutics Reports Second Quarter 2020 Financial Results - Completed enrollment of Phase 2 EMERGE trial for the interim analysis of efficacy and biomarker data in early 2021 - - On track to initiate Phase 2 SELECT trial and Phase 1 trial for JTX-8064 in 2020 - - Ended the quarter with $127.2 million in cash, cash equivalents and investments - - Company to host conference call

August 7, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2020 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commissio

June 30, 2020 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 2020 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission

June 4, 2020 8-K

Termination of a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 1, 2020 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission

June 2, 2020 DEFA14A

- DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ý Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Defin

May 6, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 6, 2020 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission F

May 6, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2020 ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE THER

May 6, 2020 EX-99.1

Jounce Therapeutics Reports First Quarter 2020 Financial Results - Updating guidance on EMERGE and SELECT Phase 2 trials due to COVID-19 - - Announcing CCR8 as JTX-1811 target; new preclinical data to be presented at the AACR 2020 June virtual meetin

Exhibit 99.1 Jounce Therapeutics Reports First Quarter 2020 Financial Results - Updating guidance on EMERGE and SELECT Phase 2 trials due to COVID-19 - - Announcing CCR8 as JTX-1811 target; new preclinical data to be presented at the AACR 2020 June virtual meeting - - Ended the quarter with $148.6 million in cash, cash equivalents and investments - - Company to host conference call and webcast tod

April 29, 2020 DEFA14A

- DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ý Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Defin

April 29, 2020 DEF 14A

- DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ý Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ý Defin

April 7, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 7, 2020 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission

April 7, 2020 EX-99.1

Exhibit 99.1 Jounce Therapeutics A Next Gen Immunotherapy Company April 2020 Legal Disclaimer Various statements concerning our future expectations, plans and prospects, including without limitation, our expectations regarding the timing, progress an

jnce040720991 Exhibit 99.1 Jounce Therapeutics A Next Gen Immunotherapy Company April 2020 Legal Disclaimer Various statements concerning our future expectations, plans and prospects, including without limitation, our expectations regarding the timing, progress and results of discovery programs, preclinical studies and clinical trials for our product candidates and any future product candidates, t

February 27, 2020 EX-21.1

List of Subsidiaries of the Registrant

Exhibit 21.1 Subsidiaries of the Registrant Name Jurisdiction of Organization Percentage Ownership Jounce Mass Securities, Inc. Massachusetts 100%

February 27, 2020 10-K

JNCE / Jounce Therapeutics, Inc. 10-K - Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2019 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE THERAP

February 27, 2020 EX-4.3

Description of Securities (incorporated by reference to Exhibit 4.3 of the Registrant’s Annual Report on Form 10-K (File No. 001-37998) filed February 27, 2020)

Exhibit 4.3 DESCRIPTION OF SECURITIES REGISTERED UNDER TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 The following description of the common stock, $0.001 par value per share (the “Common Stock”), of Jounce Therapeutics, Inc. (“us,” “our,” “we” or the “Company”), which is the only security of the Company registered under Section 12 of the Securities Exchange Act of 1934, as amended (the “Ex

February 27, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 27, 2020 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commis

February 27, 2020 S-8

As filed with the Securities and Exchange Commission on February 27, 2020

As filed with the Securities and Exchange Commission on February 27, 2020 Registration No.

February 27, 2020 EX-99.1

Jounce Therapeutics Reports Fourth Quarter and Full Year 2019 Financial Results - On track to initiate Phase 2 SELECT trial in mid-2020 and present preliminary efficacy and related biomarker data from Phase 2 EMERGE trial in 2H 2020 - - Ended 2019 wi

Exhibit 99.1 Jounce Therapeutics Reports Fourth Quarter and Full Year 2019 Financial Results - On track to initiate Phase 2 SELECT trial in mid-2020 and present preliminary efficacy and related biomarker data from Phase 2 EMERGE trial in 2H 2020 - - Ended 2019 with $170.4 million in cash, cash equivalents and investments - - Company to host conference call and webcast today at 8:00 AM ET - CAMBRID

January 23, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

8-K 1 jnce012320208-k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 21, 2020 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdict

January 13, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2020 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commiss

January 13, 2020 EX-99.1

Jounce Therapeutics A Next Gen Immunotherapy Company Legal Disclaimer Various statements concerning Jounce’s future expectations, plans and prospects, including without limitation, Jounce’s expectations regarding the timing, progress and results of d

jnce01132020exhibit991 Jounce Therapeutics A Next Gen Immunotherapy Company Legal Disclaimer Various statements concerning Jounce’s future expectations, plans and prospects, including without limitation, Jounce’s expectations regarding the timing, progress and results of discovery programs, preclinical studies and clinical trials for Jounce’s product candidates and any future product candidates, t

December 17, 2019 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 17, 2019 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commis

December 17, 2019 424B5

PROSPECTUS SUPPLEMENT (To prospectus dated May 1, 2018) Jounce Therapeutics, Inc. Common Stock

Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-223518 PROSPECTUS SUPPLEMENT (To prospectus dated May 1, 2018) $50,000,000 Jounce Therapeutics, Inc. Common Stock We have entered into a sales agreement with Cowen and Company, LLC, or Cowen, relating to shares of our common stock offered by this prospectus supplement and the accompanying prospectus. In accordance with the ter

December 17, 2019 EX-1.1

Sales Agreement, dated as of December 17, 2019, by and between the Company and Cowen and Company, LLC

Exhibit 1.1 JOUNCE THERAPEUTICS, INC. $50,000,000 COMMON STOCK SALES AGREEMENT December 17, 2019 Cowen and Company, LLC 599 Lexington Avenue New York, NY 10022 Ladies and Gentlemen: Jounce Therapeutics, Inc. (the “Company”), confirms its agreement (this “Agreement”) with Cowen and Company, LLC (“Cowen”), as follows: 1. Issuance and Sale of Shares. The Company agrees that, from time to time during

November 7, 2019 10-Q

JNCE / Jounce Therapeutics, Inc. 10-Q - Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2019 ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE

November 7, 2019 EX-10.1

License Agreement by and among the Registrant, Celgene Corporation, and Celgene RIVOT LLC, dated July 22, 2019

Exhibit 10.1 CERTAIN CONFIDENTIAL PORTIONS OF THIS EXHIBIT HAVE BEEN OMITTED AND REPLACED WITH “[***]”. SUCH IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS (I) NOT MATERIAL AND (II) WOULD LIKELY CAUSE COMPETITIVE HARM TO THE COMPANY IF DISCLOSED. LICENSE AGREEMENT by and among JOUNCE THERAPEUTICS, INC., CELGENE CORPORATION, and CELGENE RIVOT LLC dated as of July 22, 2019

November 7, 2019 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 7, 2019 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commiss

November 7, 2019 EX-99.1

Jounce Therapeutics Reports Third Quarter 2019 Financial Results - New safety and preliminary efficacy data from JTX-4014 to be presented at the SITC 2019 Annual Meeting - - JTX-4014 data supports use as a combination agent for future studies - - 201

Exhibit 99.1 Jounce Therapeutics Reports Third Quarter 2019 Financial Results - New safety and preliminary efficacy data from JTX-4014 to be presented at the SITC 2019 Annual Meeting - - JTX-4014 data supports use as a combination agent for future studies - - 2019 cash burn guidance reduced - - Company to host conference call and webcast today at 8:00 AM ET - CAMBRIDGE, Mass., November 7, 2019 - J

September 4, 2019 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 4, 2019 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commis

September 4, 2019 EX-99.1

Exhibit 99.1 Jounce Therapeutics A Next Gen Immunotherapy Company Legal Disclaimer Various statements concerning Jounce’s future expectations, plans and prospects, including without limitation, Jounce’s expectations regarding the timing, progress and

jnce090419exhibit991 Exhibit 99.1 Jounce Therapeutics A Next Gen Immunotherapy Company Legal Disclaimer Various statements concerning Jounce’s future expectations, plans and prospects, including without limitation, Jounce’s expectations regarding the timing, progress and results of discovery programs, preclinical studies and clinical trials for Jounce’s product candidates and any future product ca

August 7, 2019 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2019 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commissio

August 7, 2019 EX-99.1

Jounce Therapeutics Reports Second Quarter 2019 Financial Results - Initiated Phase 2 EMERGE trial of vopratelimab - - Completed enrollment of Phase 1 trial of JTX-4014 - - Updated strategic collaboration and established new licensing agreement with

Exhibit 99.1 Jounce Therapeutics Reports Second Quarter 2019 Financial Results - Initiated Phase 2 EMERGE trial of vopratelimab - - Completed enrollment of Phase 1 trial of JTX-4014 - - Updated strategic collaboration and established new licensing agreement with Celgene, received $50.0 million upfront - - Company to host conference call and webcast today at 8:00 AM ET - CAMBRIDGE, Mass., August 7,

August 7, 2019 10-Q

JNCE / Jounce Therapeutics, Inc. 10-Q - Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2019 ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-37998 JOUNCE THERA

July 23, 2019 8-K

Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 22, 2019 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission

June 13, 2019 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 12, 2019 JOUNCE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 001-37998 45-4870634 (State or Other Jurisdiction of Incorporation) (Commission

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