ARIA / ARIAD Pharmaceuticals, Inc. - تصريحات هيئة الأوراق المالية والبورصات، التقرير السنوي، بيان الوكيل

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الإحصائيات الأساسية
CIK 884731
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to ARIAD Pharmaceuticals, Inc.
SEC Filings (Chronological Order)
توفر هذه الصفحة قائمة كاملة ومرتبة ترتيبًا زمنيًا لتصريحات هيئة الأوراق المالية والبورصات، باستثناء تصريحات الملكية التي نقدمها في مكان آخر.
April 7, 2017 SC 13G/A

ARIA / ARIAD Pharmaceuticals, Inc. / WESTFIELD CAPITAL MANAGEMENT CO LP - WESTFIELD CAPITAL MANAGEMENT COMPANY, L.P. Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Ariad Pharmaceuticals, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 04033A100 (CUSIP Number) March 31, 2017 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which thi

February 27, 2017 15-12B

ARIAD Pharmaceuticals 15-12B

15-12B UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13 AND 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-36172 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as sp

February 21, 2017 SC 13D/A

ARIA / ARIAD Pharmaceuticals, Inc. / Sarissa Capital Management LP - AMENDMENT NO. 9 Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 9)* ARIAD Pharmaceuticals, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 04033A100 (CUSIP Number) Mark DiPaolo General Counsel Sarissa Capital Management LP 660 Steamboat Road, 3rd Floor Greenwich, CT 06830 203-302-2330

February 16, 2017 S-8 POS

ARIAD Pharmaceuticals S-8 POS

S-8 POS As filed with the Securities and Exchange Commission on February 16, 2017 Registration Nos.

February 16, 2017 S-8 POS

ARIAD Pharmaceuticals S-8 POS

S-8 POS As filed with the Securities and Exchange Commission on February 16, 2017 Registration Nos.

February 16, 2017 S-8 POS

ARIAD Pharmaceuticals S-8 POS

S-8 POS As filed with the Securities and Exchange Commission on February 16, 2017 Registration Nos.

February 16, 2017 S-8 POS

ARIAD Pharmaceuticals S-8 POS

S-8 POS As filed with the Securities and Exchange Commission on February 16, 2017 Registration Nos.

February 16, 2017 S-8 POS

ARIAD Pharmaceuticals S-8 POS

S-8 POS As filed with the Securities and Exchange Commission on February 16, 2017 Registration Nos.

February 16, 2017 S-8 POS

ARIAD Pharmaceuticals S-8 POS

S-8 POS As filed with the Securities and Exchange Commission on February 16, 2017 Registration Nos.

February 16, 2017 S-8 POS

ARIAD Pharmaceuticals S-8 POS

S-8 POS As filed with the Securities and Exchange Commission on February 16, 2017 Registration Nos.

February 16, 2017 S-8 POS

ARIAD Pharmaceuticals S-8 POS

S-8 POS As filed with the Securities and Exchange Commission on February 16, 2017 Registration Nos.

February 16, 2017 S-8 POS

ARIAD Pharmaceuticals S-8 POS

S-8 POS As filed with the Securities and Exchange Commission on February 16, 2017 Registration Nos.

February 16, 2017 8-K

Changes in Control of Registrant, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Entry into a Material Definitive Agreement, Material Modification to Rights of Security Holders, Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing, Financial Statements and Exhibits, Completion of Acquisition or Disposition of Assets, Other Events

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 16, 2017 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporati

February 16, 2017 EX-4.1

Signatures follow.

EX-4.1 Exhibit 4.1 EXECUTION VERSION SUPPLEMENTAL INDENTURE, dated as of February 16, 2017, between ARIAD Pharmaceuticals, Inc., a Delaware corporation, as issuer (the ?Company?), and Wells Fargo Bank, National Association, a national banking association, as trustee (the ?Trustee?), to the Indenture, dated as of June 17, 2014 between such parties (the ?Indenture?). All references to the ?Indenture

February 16, 2017 EX-3.2

SECOND AMENDED AND RESTATED BY-LAWS OF ARIAD PHARMACEUTICALS, INC. ARTICLE I Stockholders Meetings

EX-3.2 Exhibit 3.2 SECOND AMENDED AND RESTATED BY-LAWS OF ARIAD PHARMACEUTICALS, INC. ARTICLE I Stockholders Meetings Section 1.1. Annual Meetings. An annual meeting of stockholders shall be held for the election of directors at such date, time and place as may be fixed by resolution of the Board of Directors from time to time. Section 1.2. Special Meetings. Special meetings of stockholders for an

February 16, 2017 EX-99.1

ARIAD Pharmaceuticals, Inc. 125 Binney Street Cambridge, Massachusetts 02142

EX-99.1 Exhibit 99.1 EXECUTION VERSION ARIAD Pharmaceuticals, Inc. 125 Binney Street Cambridge, Massachusetts 02142 February 16, 2017 To: Wells Fargo Bank, National Association 150 E. 42nd St., 40th Floor, New York, NY 10017, Attention: Corporate Trust Services ? Administrator for ARIAD Pharmaceuticals, Inc. To: Holders of 3.625% Convertible Senior Notes due 2019 (the ?Notes?) issued by ARIAD Phar

February 16, 2017 EX-3.1

AMENDED AND RESTATED CERTIFICATE OF INCORPORATION ARIAD PHARMACEUTICALS, INC.

EX-3.1 Exhibit 3.1 AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF ARIAD PHARMACEUTICALS, INC. FIRST: The name of the corporation is ARIAD Pharmaceuticals, Inc. (the “Corporation”). SECOND: The address of the Corporation’s registered office in the State of Delaware is The Corporation Trust Center, 1209 Orange Street, Wilmington, Delaware 19801, New Castle County. The name of the Corporation’s

February 16, 2017 SC 14D9/A

ARIAD Pharmaceuticals SC 14D9/A

SC 14D9/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Amendment No. 5) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 ARIAD Pharmaceuticals, Inc. (Name of Subject Company) ARIAD Pharmaceuticals, Inc. (Name of Person Filing Statement) Common Stock, $.001 par value per share (Title of Class of Securities

February 16, 2017 EX-99.(A)(5)(A)

Takeda Completes Acquisition of ARIAD Pharmaceuticals, Inc. – Significantly Enhances Takeda’s Global Oncology Portfolio – – Accretive to FY2018 Underlying Core Earnings – – Reinforces Takeda’s Commitment to Developing Medicines for Patients Living wi

EX-99.(a)(5)(A) Exhibit (a)(5)(A) Takeda Completes Acquisition of ARIAD Pharmaceuticals, Inc. – Significantly Enhances Takeda’s Global Oncology Portfolio – – Accretive to FY2018 Underlying Core Earnings – – Reinforces Takeda’s Commitment to Developing Medicines for Patients Living with Cancer – Cambridge, Mass. and Osaka, Japan, February 16, 2017 – Takeda Pharmaceutical Company Limited (TSE: 4502)

February 16, 2017 SC TO-T/A

ARIA / ARIAD Pharmaceuticals, Inc. / TAKEDA PHARMACEUTICAL CO LTD - AMENDMENT NO. 5 TO SC TO-T

Amendment No. 5 to SC TO-T UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO (RULE 14D-100) Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 (Amendment No. 5) ARIAD Pharmaceuticals, Inc. (Name of Subject Company) KIKU MERGER CO., INC. (Offeror) TAKEDA PHARMACEUTICAL COMPANY LIMITED (Parent of Offeror) (Names of

February 13, 2017 EX-10.1

AMENDED AND RESTATED BUY-IN LICENSE AGREEMENT ARIAD Pharmaceuticals, Inc. ARIAD Pharmaceuticals (Europe) Sarl Incyte Corporation (as guarantor)

EX-10.1 Exhibit 10.1 AMENDED AND RESTATED BUY-IN LICENSE AGREEMENT between ARIAD Pharmaceuticals, Inc. and ARIAD Pharmaceuticals (Europe) Sarl and Incyte Corporation (as guarantor) EXECUTION VERSION TABLE OF CONTENTS ARTICLE 1 – DEFINITIONS 2 ARTICLE 2 – GRANT OF LICENSES 18 ARTICLE 3 – RESERVED TERRITORIES AND NON-COMPETITION 19 ARTICLE 4 – DEVELOPMENT AND COMMERCIALIZATION COMMITTEES 23 ARTICLE

February 13, 2017 10-Q/A

Quarterly Report - 10-Q/A

10-Q/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q/A (Amendment No. 1 to Form 10-Q) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2016 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition periods from to Commission Fi

February 13, 2017 EX-10.2

SHARE PURCHASE AGREEMENT by and among INCYTE EUROPE S.À R.L., ARIAD PHARMACEUTICALS (CAYMAN) L.P., ARIAD PHARMACEUTICALS, INC. (AS GUARANTOR), INCYTE CORPORATION (AS GUARANTOR) MAY 9, 2016 Securities and Exchange Commission pursuant to the Registrant

EX-10.2 Exhibit 10.2 EXECUTION VERSION SHARE PURCHASE AGREEMENT by and among INCYTE EUROPE S.À R.L., ARIAD PHARMACEUTICALS (CAYMAN) L.P., ARIAD PHARMACEUTICALS, INC. (AS GUARANTOR), and INCYTE CORPORATION (AS GUARANTOR) MAY 9, 2016 Portions of this Exhibit, indicated by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registr

February 10, 2017 SC 13G/A

ARIA / ARIAD Pharmaceuticals, Inc. / WESTFIELD CAPITAL MANAGEMENT CO LP - WESTFIELD CAPITAL MANAGEMENT COMPANY, L.P. Passive Investment

SC 13G/A 1 ariaa121017.htm WESTFIELD CAPITAL MANAGEMENT COMPANY, L.P. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Ariad Pharmaceuticals, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 04033A100 (CUSIP Number) December 30, 2016 (Date of Event which Requires Filing of this Stateme

February 9, 2017 SC 13G

ARIA / ARIAD Pharmaceuticals, Inc. / Wellington Management Group LLP - SEC SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* ARIAD Pharmaceuticals, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 04033A100 (CUSIP Number) December 30, 2016 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which t

February 9, 2017 SC 13G/A

ARIA / ARIAD Pharmaceuticals, Inc. / VANGUARD GROUP INC Passive Investment

ariadpharmaceuticalsinc.htm - Generated by SEC Publisher for SEC Filing SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 4 )* Name of issuer: ARIAD Pharmaceuticals Inc Title of Class of Securities: Common Stock CUSIP Number: 04033A100 Date of Event Which Requires Filing of this Statement: December 31, 2016 Check the ap

February 8, 2017 SC TO-T/A

ARIAD Pharmaceuticals AMENDMENT NO. 4 TO SC TO-T

Amendment No. 4 to SC TO-T UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO (RULE 14D-100) Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 (Amendment No. 4) ARIAD Pharmaceuticals, Inc. (Name of Subject Company) KIKU MERGER CO., INC. (Offeror) TAKEDA PHARMACEUTICAL COMPANY LIMITED (Parent of Offeror) (Names of

February 8, 2017 EX-99.(B)(1)

[TRANSLATION OF THE ORIGINAL VERSION IN JAPANESE] LOAN AGREEMENT February 8, 2017 Takeda Pharmaceutical Company Limited Sumitomo Mitsui Banking Corporation Takeda Pharmaceutical Company Limited LOAN AGREEMENT dated February 8, 2017 TABLE OF CONTENTS

EX-99.(b)(1) Exhibit (b)(1) [TRANSLATION OF THE ORIGINAL VERSION IN JAPANESE] LOAN AGREEMENT February 8, 2017 Borrower Takeda Pharmaceutical Company Limited Lender Sumitomo Mitsui Banking Corporation Takeda Pharmaceutical Company Limited LOAN AGREEMENT dated February 8, 2017 TABLE OF CONTENTS CHAPTER 1. DEFINITIONS 1 1.1 DEFINITIONS 1 CHAPTER 2. TERMS OF LOANS 5 2.1 KEY TERMS OF LOANS 5 2.2 CONDIT

February 8, 2017 EX-99.(B)(2)

[TRANSLATION OF THE ORIGINAL VERSION IN JAPANESE] LOAN AGREEMENT February 8, 2017 Takeda Pharmaceutical Company Limited The Bank of Tokyo-Mitsubishi UFJ, Ltd. Takeda Pharmaceutical Company Limited LOAN AGREEMENT dated February 8, 2017 TABLE OF CONTEN

EX-99.(b)(2) Exhibit (b)(2) [TRANSLATION OF THE ORIGINAL VERSION IN JAPANESE] LOAN AGREEMENT February 8, 2017 Borrower Takeda Pharmaceutical Company Limited Lender The Bank of Tokyo-Mitsubishi UFJ, Ltd. Takeda Pharmaceutical Company Limited LOAN AGREEMENT dated February 8, 2017 TABLE OF CONTENTS CHAPTER 1. DEFINITIONS 1 1.1 DEFINITIONS 1 CHAPTER 2. TERMS OF LOANS 5 2.1 KEY TERMS OF LOANS 5 2.2 CON

February 7, 2017 SC 14D9/A

ARIAD Pharmaceuticals SC 14D9/A

SC 14D9/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Amendment No. 4) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 ARIAD Pharmaceuticals, Inc. (Name of Subject Company) ARIAD Pharmaceuticals, Inc. (Name of Person Filing Statement) Common Stock, $.001 par value per share (Title of Class of Securities

February 6, 2017 EX-99.1

ARIAD Announces Submission of Marketing Authorization Application for Brigatinib to the European Medicines Agency

Exhibit 99.1 ARIAD Announces Submission of Marketing Authorization Application for Brigatinib to the European Medicines Agency CAMBRIDGE, Mass.-(BUSINESS WIRE)-February 6, 2017-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced the submission of a Marketing Authorization Application (MAA) for its investigational oral anaplastic lymphoma kinase (ALK) inhibitor, brigatinib, to the European M

February 6, 2017 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 6, 2017 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commi

February 1, 2017 EX-99.(A)(1)(S)

Important Notice 3 Cautionary Statement Regarding Forward-Looking Statements This presentation contains forward-looking information related to Takeda, ARIAD and the proposed acquisition of ARIAD by Takeda that involves substantial risks and uncertain

EX-99.(a)(1)(S) James Kehoe Chief Financial Officer Consolidated Financial Results FY2016 Q3 February 1, 2017 Exhibit (a)(1)(s) Important Notice 3 Cautionary Statement Regarding Forward-Looking Statements This presentation contains forward-looking information related to Takeda, ARIAD and the proposed acquisition of ARIAD by Takeda that involves substantial risks and uncertainties that could cause

February 1, 2017 EX-99.(A)(1)(T)

* * * * *

EX-99.(a)(1)(T) Exhibit (a)(1)(T) Announcer: The discussion during this call will include forward looking statements that are subject to the risks and uncertainties that could cause actual results to differ materially from those projected in the forward looking statements. Additional information regarding these factors is discussed under the cautionary statement regarding forward looking statement

February 1, 2017 SC TO-T/A

ARIAD Pharmaceuticals AMENDMENT NO. 3 TO SC TO-T

Amendment No. 3 to SC TO-T UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO (RULE 14D-100) Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 (Amendment No. 3) ARIAD Pharmaceuticals, Inc. (Name of Subject Company) KIKU MERGER CO., INC. (Offeror) TAKEDA PHARMACEUTICAL COMPANY LIMITED (Parent of Offeror) (Names of

February 1, 2017 EX-99.(A)(1)(R)

Takeda reports Q3 FY2016 results and improves year-end outlook Underlying YTD results: Revenue +7.4%, Core Earnings +23.5%, Core EPS +31.7% Full year Underlying Core Earnings increased to “high-teen growth”

EX-99.(a)(1)(R) Exhibit (a)(1)(R) Takeda reports Q3 FY2016 results and improves year-end outlook Underlying YTD results: Revenue +7.4%, Core Earnings +23.5%, Core EPS +31.7% Full year Underlying Core Earnings increased to ?high-teen growth? Strong Q3 year-to-date (YTD) results propelled by Growth Drivers ? Underlying Revenue grew +7.4%, with Takeda?s Growth Drivers (GI, Oncology, CNS and Emerging

January 30, 2017 SC TO-T/A

ARIAD Pharmaceuticals AMENDMENT NO. 2 TO SC TO-T

Amendment No. 2 to SC TO-T UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO (RULE 14D-100) Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 (Amendment No. 2) ARIAD Pharmaceuticals, Inc. (Name of Subject Company) KIKU MERGER CO., INC. (Offeror) TAKEDA PHARMACEUTICAL COMPANY LIMITED (Parent of Offeror) (Names of

January 30, 2017 SC 14D9/A

ARIAD Pharmaceuticals SC 14D9/A

SC 14D9/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Amendment No. 3) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 ARIAD Pharmaceuticals, Inc. (Name of Subject Company) ARIAD Pharmaceuticals, Inc. (Name of Person Filing Statement) Common Stock, $.001 par value per share (Title of Class of Securities

January 24, 2017 SC 14D9/A

ARIAD Pharmaceuticals SC 14D9/A

SC 14D9/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Amendment No. 2) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 ARIAD Pharmaceuticals, Inc. (Name of Subject Company) ARIAD Pharmaceuticals, Inc. (Name of Person Filing Statement) Common Stock, $.001 par value per share (Title of Class of Securities

January 24, 2017 SC TO-T/A

ARIAD Pharmaceuticals SC TO-T/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO (RULE 14D-100) Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 (Amendment No. 1) ARIAD Pharmaceuticals, Inc. (Name of Subject Company) KIKU MERGER CO., INC. (Offeror) TAKEDA PHARMACEUTICAL COMPANY LIMITED (Parent of Offeror) (Names of Filing Persons) Common sto

January 24, 2017 SC 14D9/A

ARIAD Pharmaceuticals SC 14D9/A

SC 14D9/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Amendment No. 1) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 ARIAD Pharmaceuticals, Inc. (Name of Subject Company) ARIAD Pharmaceuticals, Inc. (Name of Person Filing Statement) Common Stock, $.001 par value per share (Title of Class of Securities

January 24, 2017 EX-99.(A)(13)

ARIAD Pharmaceuticals, Inc. Employee FAQs January 23, 2017

EX-99.(a)(13) Exhibit (a)(13) ARIAD Pharmaceuticals, Inc. Employee FAQs January 23, 2017 1. What was announced? Why is ARIAD entering into this transaction with Takeda? ? On January 9, 2017, we announced that ARIAD has entered into a definitive agreement to be acquired by Takeda. ? The transaction with Takeda will allow us to accelerate ARIAD?s mission to discover, develop and deliver precision th

January 19, 2017 SC 14D9

ARIAD Pharmaceuticals SC 14D9

SC 14D9 Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

January 19, 2017 EX-99.(A)(1)(A)

Offer to Purchase for Cash All Outstanding Shares of Common Stock ARIAD Pharmaceuticals, Inc. $24.00 Net Per Share Kiku Merger Co., Inc. an indirect wholly-owned subsidiary of Takeda Pharmaceutical Company Limited

EX-99.(a)(1)(A) Table of Contents Exhibit (a)(1)(A) Offer to Purchase for Cash All Outstanding Shares of Common Stock of ARIAD Pharmaceuticals, Inc. at $24.00 Net Per Share by Kiku Merger Co., Inc. an indirect wholly-owned subsidiary of Takeda Pharmaceutical Company Limited THE OFFER AND WITHDRAWAL RIGHTS WILL EXPIRE AT 11:59 P.M. EASTERN TIME ON WEDNESDAY, FEBRUARY 15, 2017, UNLESS THE OFFER IS E

January 19, 2017 EX-99.(A)(1)(F)

Notice of Offer to Purchase for Cash All Outstanding Shares of Common Stock ARIAD Pharmaceuticals, Inc. a Delaware corporation $24.00 Net Per Share Pursuant to the Offer to Purchase Dated January 19, 2017 Kiku Merger Co., Inc. an indirect wholly-owne

EX-99.(a)(1)(F) Exhibit (a)(1)(F) This announcement is neither an offer to purchase nor a solicitation of an offer to sell Shares (as defined below), and the provisions herein are subject in their entirety to the provisions of the Offer (as defined below). The Offer is made solely pursuant to the Offer to Purchase, dated January 19, 2017, and the related Letter of Transmittal and any amendments or

January 19, 2017 EX-99.(A)(1)(B)

LETTER OF TRANSMITTAL To Tender Shares of Common Stock ARIAD Pharmaceuticals, Inc. a Delaware corporation $24.00 NET PER SHARE Pursuant to the Offer to Purchase Dated January 19, 2017 Kiku Merger Co., Inc. an indirect wholly-owned subsidiary of Taked

EX-99.(a)(1)(B) Exhibit (a)(1)(B) LETTER OF TRANSMITTAL To Tender Shares of Common Stock of ARIAD Pharmaceuticals, Inc. a Delaware corporation at $24.00 NET PER SHARE Pursuant to the Offer to Purchase Dated January 19, 2017 by Kiku Merger Co., Inc. an indirect wholly-owned subsidiary of Takeda Pharmaceutical Company Limited THE OFFER AND WITHDRAWAL RIGHTS WILL EXPIRE AT 11:59 P.M. EASTERN TIME ON

January 19, 2017 EX-99.(A)(1)(C)

NOTICE OF GUARANTEED DELIVERY To Tender Shares of Common Stock ARIAD Pharmaceuticals, Inc. a Delaware corporation $24.00 NET PER SHARE Pursuant to the Offer to Purchase Dated January 19, 2017 Kiku Merger Co., Inc. an indirect wholly-owned subsidiary

EX-99.(a)(1)(C) Exhibit (a)(1)(C) NOTICE OF GUARANTEED DELIVERY To Tender Shares of Common Stock of ARIAD Pharmaceuticals, Inc. a Delaware corporation at $24.00 NET PER SHARE Pursuant to the Offer to Purchase Dated January 19, 2017 by Kiku Merger Co., Inc. an indirect wholly-owned subsidiary of Takeda Pharmaceutical Company Limited THE OFFER AND WITHDRAWAL RIGHTS WILL EXPIRE AT 11:59 P.M. EASTERN

January 19, 2017 EX-99.(D)(2)

[Remainder of Page Intentionally Left Blank]

EX-99.(d)(2) Exhibit (d) (2) EXECUTION COPY December 18, 2016 Takeda Pharmaceutical Company Limited 1-1, Doshomachi 4-chome Chuo-ku, Osaka-shi Osaka 540-8645, Japan Ladies and Gentlemen: In connection with your consideration of a possible consensual transaction (the “Transaction”) with ARIAD Pharmaceuticals, Inc. and/or its affiliates (collectively, with such affiliates, the “Company”), the Compan

January 19, 2017 EX-99.(A)(1)(Q)

Takeda Commences Cash Tender Offer for all Outstanding Shares of ARIAD Pharmaceuticals, Inc.

EX-99.(a)(1)(Q) Exhibit (a)(1)(Q) Takeda Commences Cash Tender Offer for all Outstanding Shares of ARIAD Pharmaceuticals, Inc. Osaka, Japan, January 20, 2017 and Cambridge, Massachusetts, USA, January 19, 2017 ? Takeda Pharmaceutical Company Limited (TSE: 4502) (?Takeda?) today announced the commencement of the cash tender offer by its wholly-owned indirect subsidiary, Kiku Merger Co., Inc., for a

January 19, 2017 EX-99.(A)(1)(E)

Offer to Purchase for Cash All Outstanding Shares of Common Stock ARIAD Pharmaceuticals, Inc. a Delaware corporation $24.00 Net Per Share Pursuant to the Offer to Purchase Dated January 19, 2017 Kiku Merger Co., Inc. an indirect wholly-owned subsidia

EX-99.(a)(1)(E) Exhibit (a)(1)(E) Offer to Purchase for Cash All Outstanding Shares of Common Stock of ARIAD Pharmaceuticals, Inc. a Delaware corporation at $24.00 Net Per Share Pursuant to the Offer to Purchase Dated January 19, 2017 by Kiku Merger Co., Inc. an indirect wholly-owned subsidiary of Takeda Pharmaceutical Company Limited THE OFFER AND WITHDRAWAL RIGHTS WILL EXPIRE AT 11:59 P.M. EASTE

January 19, 2017 EX-99.(D)(3)

2

EX-99.(d)(3) Exhibit (d) (3) Better Health, Brighter Future December 26, 2016 Board of Directors Ariad Pharmaceuticals, Inc. 26 Landsdowne Street Cambridge, MA 02139 Ladies and Gentlemen: This letter agreement (this “Letter Agreement”) sets forth certain understandings between Takeda Pharmaceutical Company Limited (“Buyer”), and Ariad Pharmaceuticals, Inc. (the “Company”) with respect to discussio

January 19, 2017 SC TO-T

ARIAD Pharmaceuticals SC TO-T

SC TO-T UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 ARIAD PHARMACEUTICALS, INC. (Name of Subject Company) KIKU MERGER CO., INC. (Offeror) TAKEDA PHARMACEUTICAL COMPANY LIMITED (Parent of Offeror) (Names of Filing Persons) Common stock, par value $0.001 per

January 19, 2017 EX-99.(A)(1)(D)

Offer to Purchase for Cash All Outstanding Shares of Common Stock ARIAD Pharmaceuticals, Inc. a Delaware corporation $24.00 Net Per Share Pursuant to the Offer to Purchase Dated January 19, 2017 Kiku Merger Co., Inc. an indirect wholly-owned subsidia

EX-99.(a)(1)(D) Exhibit (a)(1)(D) Offer to Purchase for Cash All Outstanding Shares of Common Stock of ARIAD Pharmaceuticals, Inc. a Delaware corporation at $24.00 Net Per Share Pursuant to the Offer to Purchase Dated January 19, 2017 by Kiku Merger Co., Inc. an indirect wholly-owned subsidiary of Takeda Pharmaceutical Company Limited THE OFFER AND WITHDRAWAL RIGHTS WILL EXPIRE AT 11:59 P.M. EASTE

January 18, 2017 SC 13D

ARIA / ARIAD Pharmaceuticals, Inc. / TAKEDA PHARMACEUTICAL CO LTD - SC 13D Activist Investment

SC 13D SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.

January 18, 2017 EX-99.3

[Remainder of Page Intentionally Left Blank]

EX-99.3 EXHIBIT 3 EXECUTION COPY December 18, 2016 Takeda Pharmaceutical Company Limited 1-1, Doshomachi 4-chome Chuo-ku, Osaka-shi Osaka 540-8645, Japan Ladies and Gentlemen: In connection with your consideration of a possible consensual transaction (the “Transaction”) with ARIAD Pharmaceuticals, Inc. and/or its affiliates (collectively, with such affiliates, the “Company”), the Company is prepar

January 18, 2017 EX-99.4

AGREEMENT OF JOINT FILING

99.EX-4 EXHIBIT 4 AGREEMENT OF JOINT FILING This joint filing agreement (this “Agreement”) is made and entered into as of this 18th day of January, 2017, by and among Takeda Pharmaceutical Company Limited, Kiku Merger Co., Inc., TPA Holding I, Inc. and TPA Holding II, Inc. The parties to this Agreement hereby agree to prepare jointly and file timely (and otherwise to deliver as appropriate) all fi

January 11, 2017 EX-99.1

* * * * *

EX-99.1 Exhibit 99.1 * * * * * Christophe Weber: Thank you. Good afternoon everyone. It?s a great pleasure to be with you again this year. What I?m planning to do is to give you an update about Takeda and the transformation of Takeda. We started this transformation two years ago. Of course, we had a big event today with the acquisition of ARIAD. I will share with you that perspective as well about

January 11, 2017 EX-99.2

We also urge you to read both the tender offer statement that will be filed by Takeda with the SEC and the solicitation recommendation statement that will be filed by ARIAD with the SEC when they become available because they will contain important i

EX-99.2 Exhibit 99.2 The discussion during this call will include forward-looking statements that are subject to the risks and uncertainties that could cause actual results to differ materially from those projected in the forward-looking statements. Additional information regarding these factors is discussed under the ?Cautionary Statement Regarding Forward-Looking Statements? section in the press

January 11, 2017 SC TO-C

ARIAD Pharmaceuticals SC TO-C

SC TO-C UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 ARIAD PHARMACEUTICALS, INC. (Name of Subject Company) KIKU MERGER CO., INC. (Offeror) TAKEDA PHARMACEUTICAL COMPANY LIMITED (Parent of Offeror) (Names of Filing Persons) Common stock, par value $0.001 per

January 10, 2017 SC TO-C

ARIAD Pharmaceuticals SC TO-C

SC TO-C UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 ARIAD PHARMACEUTICALS, INC. (Name of Subject Company) KIKU MERGER CO., INC. (Offeror) TAKEDA PHARMACEUTICAL COMPANY LIMITED (Parent of Offeror) (Names of Filing Persons) Common stock, par value $0.001 per

January 10, 2017 EX-99.2

Important Notice Forward-Looking Statements This presentation contains forward-looking statements regarding Takeda’s future business, financial position and results of operations, including estimates, forecasts, targets and plans. These forward-looki

EX-99.2 Conference Call Takeda to Acquire ARIAD Pharmaceuticals Significantly Enhances Takeda's Global Oncology Portfolio January 10, 2017 Christophe Weber President & Chief Executive Officer Exhibit 99.2 Important Notice Forward-Looking Statements This presentation contains forward-looking statements regarding Takeda?s future business, financial position and results of operations, including estim

January 10, 2017 EX-99.1

Important Notice Forward-Looking Statements This presentation contains forward-looking statements regarding Takeda’s future business, financial position and results of operations, including estimates, forecasts, targets and plans. These forward-looki

EX-99.1 Strategic Transformation Driving Profitable Growth J.P. Morgan Healthcare Conference 2017 January 9, 2017 Christophe Weber President & Chief Executive Of?cer Exhibit 99.1 Important Notice Forward-Looking Statements This presentation contains forward-looking statements regarding Takeda?s future business, financial position and results of operations, including estimates, forecasts, targets a

January 10, 2017 EX-99.2

ARIAD Enters into Definitive Agreement to be Acquired by Takeda for $5.2 billion ARIAD Stockholders to Receive $24.00 per Share in Cash

Exhibit 99.2 News Release FOR IMMEDIATE RELEASE ARIAD Enters into Definitive Agreement to be Acquired by Takeda for $5.2 billion ARIAD Stockholders to Receive $24.00 per Share in Cash Cambridge, Mass. January 9, 2017 ? ARIAD Pharmaceuticals (NASDAQ:ARIA) (?ARIAD?) today announced it has entered into a definitive agreement to be acquired by Takeda Pharmaceutical Company Limited (TSE: 4502) (?Takeda

January 10, 2017 EX-10.1

CALL OPTION AND WARRANT TERMINATION AGREEMENT

Exhibit 10.1 CALL OPTION AND WARRANT TERMINATION AGREEMENT This CALL OPTION AND WARRANT TERMINATION AGREEMENT (this ?Termination Agreement?) is made as of January 8, 2017 between JPMorgan Chase Bank, National Association, London Branch (?Dealer?) and ARIAD Pharmaceuticals, Inc. (?Counterparty?), a Delaware corporation. WHEREAS, Dealer and Counterparty are parties to the base call option transactio

January 10, 2017 EX-99.4

ARIAD Pharmaceuticals, Inc. 125 Binney Street Cambridge, Massachusetts 02142

Exhibit 99.4 ARIAD Pharmaceuticals, Inc. 125 Binney Street Cambridge, Massachusetts 02142 January 9, 2017 To: Wells Fargo Bank, National Association 150 E. 42nd St., 40th Floor, New York, NY 10017, Attention: Corporate Trust Services ? Administrator for ARIAD Pharmaceuticals, Inc. To: Holders of 3.625% Convertible Senior Notes due 2019 (the ?Notes?) issued by ARIAD Pharmaceuticals, Inc.; CUSIP: 04

January 10, 2017 EX-99.1

Takeda to Acquire ARIAD Pharmaceuticals, Inc. — Significantly Enhances Takeda’s Global Oncology Portfolio — — Accretive to FY2018 Underlying Core Earnings —

Exhibit 99.1 Takeda to Acquire ARIAD Pharmaceuticals, Inc. ? Significantly Enhances Takeda?s Global Oncology Portfolio ? ? Accretive to FY2018 Underlying Core Earnings ? ? Reinforces Takeda?s Commitment to Developing Medicines for Patients Living with Cancer ? Strategic Highlights ? Highly strategic deal which transforms global oncology portfolio and pipeline by expanding into solid tumors and rei

January 10, 2017 EX-99.3

TENDER AND SUPPORT AGREEMENT

Exhibit 99.3 TENDER AND SUPPORT AGREEMENT This TENDER AND SUPPORT AGREEMENT (this ?Agreement?), dated as of January 8, 2017, is entered into by and among Takeda Pharmaceutical Company Limited, a corporation organized under the laws of Japan (?Parent?), Kiku Merger Co., Inc., a Delaware corporation and an indirect wholly-owned subsidiary of Parent (?Merger Sub?), and the individual or entity set fo

January 10, 2017 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 8, 2017 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commis

January 10, 2017 EX-2.1

Agreement and Plan of Merger between ARIAD Pharmaceuticals, Inc., Takeda Pharmaceutical Company Limited and Kiku Merger Co., Inc., dated January 8, 2017 (incorporated by reference to Exhibit 2.1 to the Current Report of ARIAD Pharmaceuticals, Inc. on Form 8-K filed with the SEC on January 10, 2017)

Exhibit 2.1 EXECUTION VERSION AGREEMENT AND PLAN OF MERGER between ARIAD PHARMACEUTICALS, INC., TAKEDA PHARMACEUTICAL COMPANY LIMITED, and KIKU MERGER CO., INC. JANUARY 8, 2017 TABLE OF CONTENTS Page ARTICLE 1 DEFINITIONS 2 Section 1.01 Definitions 2 Section 1.02 Other Definitional and Interpretative Provisions 14 ARTICLE 2 THE OFFER AND THE MERGER 14 Section 2.01 The Offer 14 Section 2.02 Company

January 10, 2017 SC 13D/A

ARIA / ARIAD Pharmaceuticals, Inc. / Sarissa Capital Management LP - SC 13D/A Activist Investment

SC 13D/A 1 d285727dsc13da.htm SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 8 )* ARIAD Pharmaceuticals, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 04033A100 (CUSIP Number) Mark DiPaolo General Counsel Sarissa Capital Management LP 660 Steamboat Road Gree

January 9, 2017 EX-99.4

Takeda Oncology

EX-99.4 Exhibit 99.4 Takeda Oncology We are excited to announce we?ve entered into a definitive agreement to acquire Ariad Pharmaceuticals. Read important information here: http://takeda.news/2j9ordj

January 9, 2017 EX-99.5

Takeda Oncology

EX-99.5 Exhibit 99.5 Takeda Oncology We are excited to announce we?ve entered into a definitive agreement to acquire Ariad Pharmaceuticals. Read the full announcement: http://bit.ly/2iUrqX7 and important information below: Additional Information The tender offer described in this document has not yet commenced. This document is provided for informational purposes only and does not constitute an of

January 9, 2017 EX-99.6

A Message from Takeda President and CEO Christophe Weber re: Takeda Acquisition of Ariad

EX-99.6 Exhibit 99.6 A Message from Takeda President and CEO Christophe Weber re: Takeda Acquisition of Ariad January 9, 2017 Dear all, Following the announcement that Takeda has reached agreement to acquire Ariad Pharmaceuticals, I?d like to extend a warm greeting on behalf of everyone at Takeda. Ariad has an exciting portfolio of targeted therapies that are highly complementary to Takeda?s oncol

January 9, 2017 EX-99.3

#BREAKING: Excited to announce our acquisition of @AriadPharm. Read important information here: http://takeda.news/2j9ordj

EX-99.3 Exhibit 99.3 @TakedaOncology #BREAKING: Excited to announce our acquisition of @AriadPharm. Read important information here: http://takeda.news/2j9ordj

January 9, 2017 EX-99.1

ARIAD Enters into Definitive Agreement to be Acquired by Takeda for $5.2 billion ARIAD Stockholders to Receive $24.00 per Share in Cash

EX-99.1 Exhibit 99.1 News Release FOR IMMEDIATE RELEASE ARIAD Enters into Definitive Agreement to be Acquired by Takeda for $5.2 billion ARIAD Stockholders to Receive $24.00 per Share in Cash Cambridge, Mass. January 9, 2017 ? ARIAD Pharmaceuticals (NASDAQ:ARIA) (?ARIAD?) today announced it has entered into a definitive agreement to be acquired by Takeda Pharmaceutical Company Limited (TSE: 4502)

January 9, 2017 EX-99.2

Takeda to Acquire ARIAD Pharmaceuticals, Inc. – Significantly Enhances Takeda’s Global Oncology Portfolio – – Accretive to FY2018 Underlying Core Earnings – – Reinforces Takeda’s Commitment to Developing Medicines for Patients Living with Cancer –

EX-99.2 Exhibit 99.2 Takeda to Acquire ARIAD Pharmaceuticals, Inc. ? Significantly Enhances Takeda?s Global Oncology Portfolio ? ? Accretive to FY2018 Underlying Core Earnings ? ? Reinforces Takeda?s Commitment to Developing Medicines for Patients Living with Cancer ? Strategic Highlights ? Highly strategic deal which transforms global oncology portfolio and pipeline by expanding into solid tumors

January 9, 2017 SC TO-C

ARIAD Pharmaceuticals SC TO-C

SC TO-C UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 ARIAD PHARMACEUTICALS, INC. (Name of Subject Company) KIKU MERGER CO., INC. (Offeror) TAKEDA PHARMACEUTICAL COMPANY LIMITED (Parent of Offeror) (Names of Filing Persons) Common stock, par value $0.001 per

January 9, 2017 SC14D9C

ARIAD Pharmaceuticals SC14D9C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 ARIAD Pharmaceuticals, Inc. (Name of Subject Company) ARIAD Pharmaceuticals, Inc. (Name of Person Filing Statement) Common Stock, $0.001 par value per share (Title of Class of Securities) 04033A100

January 9, 2017 EX-99.3

Subject Line: CEO Message Regarding ARIAD/Takeda Transaction Announcement

Exhibit 99.3 Subject Line: CEO Message Regarding ARIAD/Takeda Transaction Announcement January 9, 2017 Dear colleagues, I have important news that I want to share with you directly ? we have just announced that ARIAD has entered into a definitive agreement to be acquired by Takeda Pharmaceuticals. This transaction not only allows us to accelerate ARIAD?s mission to discover, develop and deliver pr

January 9, 2017 EX-99.2

ARIAD Enters into Definitive Agreement to be Acquired by Takeda for $5.2 billion ARIAD Stockholders to Receive $24.00 per Share in Cash

Exhibit 99.2 News Release FOR IMMEDIATE RELEASE ARIAD Enters into Definitive Agreement to be Acquired by Takeda for $5.2 billion ARIAD Stockholders to Receive $24.00 per Share in Cash Cambridge, Mass. January 9, 2017 ? ARIAD Pharmaceuticals (NASDAQ:ARIA) (?ARIAD?) today announced it has entered into a definitive agreement to be acquired by Takeda Pharmaceutical Company Limited (TSE: 4502) (?Takeda

January 9, 2017 EX-99.4

ARIAD Pharmaceuticals, Inc. 125 Binney Street Cambridge, Massachusetts 02142

Exhibit 99.4 ARIAD Pharmaceuticals, Inc. 125 Binney Street Cambridge, Massachusetts 02142 January 9, 2017 To: Wells Fargo Bank, National Association 150 E. 42nd St., 40th Floor, New York, NY 10017, Attention: Corporate Trust Services ? Administrator for ARIAD Pharmaceuticals, Inc. To: Holders of 3.625% Convertible Senior Notes due 2019 (the ?Notes?) issued by ARIAD Pharmaceuticals, Inc.; CUSIP: 04

January 9, 2017 EX-99.1

Takeda to Acquire ARIAD Pharmaceuticals, Inc. — Significantly Enhances Takeda’s Global Oncology Portfolio — — Accretive to FY2018 Underlying Core Earnings —

Exhibit 99.1 Takeda to Acquire ARIAD Pharmaceuticals, Inc. — Significantly Enhances Takeda’s Global Oncology Portfolio — — Accretive to FY2018 Underlying Core Earnings — — Reinforces Takeda’s Commitment to Developing Medicines for Patients Living with Cancer — Strategic Highlights · Highly strategic deal which transforms global oncology portfolio and pipeline by expanding into solid tumors and rei

December 8, 2016 EX-99.2

ARIAD Announces Data Presentations at American Society of Hematology Meeting ~Final report from Phase 1 study of ponatinib includes approximately five-year median follow-up; Major Molecular Response (MMR) rate was 56 percent ~Pooled Phase 1 and PACE

Exhibit 99.2 ARIAD Announces Data Presentations at American Society of Hematology Meeting ~Final report from Phase 1 study of ponatinib includes approximately five-year median follow-up; Major Molecular Response (MMR) rate was 56 percent ~Pooled Phase 1 and PACE analysis of CP-CML patients with T315I shows 83 percent estimated to maintain major cytogenetic response at four years CAMBRIDGE, Mass. &

December 8, 2016 EX-99.3

ARIAD’s Investigational Medicine Brigatinib Demonstrated 15.6 Month Systemic Median Progression-Free Survival in ALTA Study - Analysis Also Demonstrated Intracranial Median Progression-Free Survival (PFS) of 18.4 Months - 55 Percent Confirmed Systemi

Exhibit 99.3 ARIAD?s Investigational Medicine Brigatinib Demonstrated 15.6 Month Systemic Median Progression-Free Survival in ALTA Study - Analysis Also Demonstrated Intracranial Median Progression-Free Survival (PFS) of 18.4 Months - 55 Percent Confirmed Systemic Objective Response Rate - Investor and Analyst Webcast to be Held Today at 4:00 p.m. Central European Time (10:00 a.m. Eastern Time) CA

December 8, 2016 8-K

ARIAD Pharmaceuticals ARIAD PHARMACEUTICALS, INC. 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 5, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commi

December 8, 2016 EX-99.1

ARIAD Presents Updated Brigatinib Data with 18.4 Months Median Intracranial Progression Free Survival (PFS) in ALK+ NSCLC Patients with CNS Metastases at the World Conference on Lung Cancer ~ Investor and analyst call to be held on Wednesday, Decembe

Exhibit 99.1 ARIAD Presents Updated Brigatinib Data with 18.4 Months Median Intracranial Progression Free Survival (PFS) in ALK+ NSCLC Patients with CNS Metastases at the World Conference on Lung Cancer ~ Investor and analyst call to be held on Wednesday, December 7 at 4:00 p.m. Central European Time (10:00 a.m. Eastern Time) CAMBRIDGE, Mass. & VIENNA-(BUSINESS WIRE)-December 5, 2016-ARIAD Pharmac

December 7, 2016 EX-10.1

Executive Employment Agreement

EX-10.1 Exhibit 10.1 Executive Employment Agreement ARIAD Pharmaceuticals, Inc. (the “Company”) a Delaware corporation, and Timothy P. Clackson, Ph.D. (the “Employee”) enter into the following Executive Employment Agreement as of the 1st day of December, 2016 (hereafter, the “Agreement”). WHEREAS, the Company and the Employee previously entered into an executive agreement on May 15, 2010, as amend

December 7, 2016 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

8-K 1 d238507d8k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of Earliest Event Reported): December 1, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or Other Jurisdiction

December 7, 2016 EX-10.2

Executive Employment Agreement

EX-10.2 Exhibit 10.2 Executive Employment Agreement ARIAD Pharmaceuticals, Inc. (the ?Company?), a Delaware corporation, and Daniel M. Bollag, Ph.D. (the ?Employee?) enter into the following Executive Employment Agreement as of the 1st day of December, 2016 (hereafter, the ?Agreement?). WHEREAS, the Company and the Employee previously entered into an executive agreement on May 15, 2010, as amended

December 7, 2016 EX-10.3

Executive Employment Agreement

EX-10.3 Exhibit 10.3 Executive Employment Agreement ARIAD Pharmaceuticals, Inc. (the ?Company?), a Delaware corporation, and Hugh M. Cole (the ?Employee?) enter into the following Executive Employment Agreement as of the 1st day of December, 2016 (hereafter, the ?Agreement?). WHEREAS, the Company and the Employee previously entered into an executive agreement on February 28, 2014, which the Compan

December 7, 2016 CORRESP

ARIAD Pharmaceuticals ESP

Mail Stop 4546 December 7, 2016 VIA EDGAR AND HAND DELIVERY Mr. Jim B. Rosenberg Senior Assistant Chief Accountant Division of Corporation Finance U.S. Securities and Exchange Commission 100 F Street, N.E. Washington, D.C. 20549-7010 Re: ARIAD Pharmaceuticals, Inc. Form 10-K for the Fiscal Year Ended December 31, 2015 Filed February 29, 2016 Form 10-Q for the Quarterly Period Ended September 30, 2

November 30, 2016 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 29, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Comm

November 30, 2016 EX-99.1

ARIAD Announces FDA Full Approval and Label Update for Iclusig® (ponatinib) Based on Long-Term Efficacy and Safety Data from Phase 2 PACE Clinical Trial

Exhibit 99.1 ARIAD Announces FDA Full Approval and Label Update for Iclusig? (ponatinib) Based on Long-Term Efficacy and Safety Data from Phase 2 PACE Clinical Trial Full approval granted through completion of accelerated approval commitments for rare cancer patients who may have no other targeted treatment options New label update for CP-CML reflects 55 percent major cytogenetic response rate (MC

November 18, 2016 8-K

ARIAD Pharmaceuticals ARIAD PHARMACEUTICALS, INC. 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 16, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Comm

November 18, 2016 EX-99.1

ARIAD Announces Data Presentations at the World Conference on Lung Cancer ~ Investigational Medicine Brigatinib Demonstrates 53 Percent Confirmed Objective Response Rate and 15.6-Month Median Progression-Free Survival by Independent Review Committee

Exhibit 99.1 ARIAD Announces Data Presentations at the World Conference on Lung Cancer ~ Investigational Medicine Brigatinib Demonstrates 53 Percent Confirmed Objective Response Rate and 15.6-Month Median Progression-Free Survival by Independent Review Committee Assessment in ALTA Study Abstract ~ WCLC Oral and Poster Presentations to Include Approximately Three Months of Additional Follow-up Comp

November 8, 2016 10-Q

Quarterly Report - 10-Q Q3 2016 FILING

Document Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

November 8, 2016 EX-10.1

Executive Employment Agreement

Exhibit 10.1 Executive Employment Agreement ARIAD Pharmaceuticals, Inc. (the “Company”) a Delaware corporation, and Elona Kogan (the “Employee”) enter into the following Executive Employment Agreement as of the 15th day of July, 2016 (hereafter, the “Agreement”). WHEREAS, the Company wishes to offer the Employee employment according to the following terms and conditions; WHEREAS, the Employee wish

November 7, 2016 EX-99.1

ARIAD Reports Third Quarter 2016 Financial Results ~Brigatinib granted Priority Review with a PDUFA date of April 29, 2017 ~ Regulatory approval of Iclusig® in Japan ~ Enrollment continues in OPTIC, OPTIC-2L, ALTA-1L, AP32788 trials highlighting ARIA

Exhibit 99.1 ARIAD Reports Third Quarter 2016 Financial Results ~Brigatinib granted Priority Review with a PDUFA date of April 29, 2017 ~ Regulatory approval of Iclusig? in Japan ~ Enrollment continues in OPTIC, OPTIC-2L, ALTA-1L, AP32788 trials highlighting ARIAD's continued R&D investment for patients with rare cancers ~ U.S. product revenue of $33.6 million for the quarter (~66% growth from pri

November 7, 2016 8-K

ARIAD Pharmaceuticals ARIAD PHARMACEUTICALS, INC. 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 7, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commi

October 31, 2016 8-K

Current Report

8-K 1 a51450187.htm ARIAD PHARMACEUTICALS, INC. 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 31, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (

October 31, 2016 EX-99.1

ARIAD Announces U.S. Food and Drug Administration Acceptance of NDA Filing for Brigatinib Brigatinib Granted Priority Review, with a PDUFA Date of April 29, 2017

Exhibit 99.1 ARIAD Announces U.S. Food and Drug Administration Acceptance of NDA Filing for Brigatinib Brigatinib Granted Priority Review, with a PDUFA Date of April 29, 2017 CAMBRIDGE, Mass.-(BUSINESS WIRE)-October 31, 2016-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that the U.S. Food and Drug Administration (FDA) has accepted for review the New Drug Application (NDA) for ARIAD?s

September 29, 2016 EX-99.1

ARIAD Announces Regulatory Approval for Iclusig® (ponatinib) in Japan Approval triggers $10 million milestone payment to ARIAD

Exhibit 99.1 ARIAD Announces Regulatory Approval for Iclusig? (ponatinib) in Japan Approval triggers $10 million milestone payment to ARIAD CAMBRIDGE, Mass.-(BUSINESS WIRE)-September 28, 2016-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that its partner Otsuka Pharmaceutical Co., Ltd. (Otsuka) has received approval from the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) f

September 29, 2016 8-K

ARIAD Pharmaceuticals ARIAD PHARMACEUTICALS, INC. 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 28, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Com

August 30, 2016 EX-99.1

ARIAD Completes Rolling Submission of New Drug Application for Brigatinib to the U.S. Food and Drug Administration

Exhibit 99.1 ARIAD Completes Rolling Submission of New Drug Application for Brigatinib to the U.S. Food and Drug Administration CAMBRIDGE, Mass.-(BUSINESS WIRE)-August 30, 2016-ARIAD Pharmaceuticals, Inc. (NASDAQ:ARIA) today announced it has completed the rolling submission of the New Drug Application (NDA) for its investigational anaplastic lymphoma kinase (ALK) inhibitor, brigatinib, to the U.S.

August 30, 2016 8-K

Current Report

8-K 1 a51410050.htm ARIAD PHARMACEUTICALS, INC. 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 30, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (S

August 8, 2016 10-Q

ARIAD Pharmaceuticals Q2 2016 10-Q - AS OF 6/30/16 (Quarterly Report)

Document Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

August 8, 2016 EX-10.1

AMENDED AND RESTATED BUY-IN LICENSE AGREEMENT ARIAD Pharmaceuticals, Inc. ARIAD Pharmaceuticals (Europe) Sarl Incyte Corporation (as guarantor) TABLE OF CONTENTS

Exhibit 10.1 EXECUTION VERSION AMENDED AND RESTATED BUY-IN LICENSE AGREEMENT between ARIAD Pharmaceuticals, Inc. and ARIAD Pharmaceuticals (Europe) Sarl and Incyte Corporation (as guarantor) TABLE OF CONTENTS ARTICLE 1 – DEFINITIONS 2 ARTICLE 2 – GRANT OF LICENSES 18 ARTICLE 3 – RESERVED TERRITORIES AND NON-COMPETITION 19 ARTICLE 4 – DEVELOPMENT AND COMMERCIALIZATION COMMITTEES 23 ARTICLE 5 – DEVE

August 8, 2016 EX-10.3

AMENDMENT NO. 1 TO RIAA

Exhibit 10.3 EXECUTION VERSION AMENDMENT NO. 1 TO RIAA This AMENDMENT NO. 1 TO RIAA (this “Amendment”) is made and entered into as of May 9, 2016 by and between ARIAD Pharmaceuticals, Inc., a Delaware corporation (“ARIAD” or the “Company”), and PDL BioPharma, Inc., a Delaware corporation (“Purchaser”), each party to that certain Revenue Interest Assignment Agreement, dated as of July 28, 2015 (as

August 8, 2016 EX-10.8

ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN FORM OF RESTRICTED STOCK UNIT AGREEMENT

Exhibit 10.8 ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN FORM OF RESTRICTED STOCK UNIT AGREEMENT This Restricted Stock Unit Agreement certifies that, pursuant to the ARIAD Pharmaceuticals, Inc. 2014 Long Term Incentive Plan (the “2014 Plan”), the Board of Directors of ARIAD Pharmaceuticals, Inc. (the “Company”) has granted the right to receive shares of common stock, $.001 par value

August 8, 2016 EX-10.4

PARTIAL RELEASE OF SECURITY INTEREST

Exhibit 10.4 EXECUTION VERSION PARTIAL RELEASE OF SECURITY INTEREST THIS PARTIAL RELEASE OF SECURITY INTEREST (this “Release”), dated as of May 9, 2016 is made by PDL BIOPHARMA, INC., a Delaware corporation (the “Purchaser”) party to that certain Revenue Interest Assignment Agreement, dated as of July 28, 2015 by and between ARIAD PHARMACEUTICALS, INC., a Delaware corporation, (the “Company”) (as

August 8, 2016 EX-10.9

ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN FORM OF PERFORMANCE SHARE AGREEMENT

Exhibit 10.9 ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN FORM OF PERFORMANCE SHARE AGREEMENT This Performance Share Agreement certifies that, pursuant to the ARIAD Pharmaceuticals, Inc. 2014 Long Term Incentive Plan (the “2014 Plan”), the Compensation Committee of the Board of Directors of ARIAD Pharmaceuticals, Inc. (the “Company”) has granted the Participant the right to receive sh

August 8, 2016 EX-10.2

SHARE PURCHASE AGREEMENT by and among INCYTE EUROPE S.à r.l., ARIAD PHARMACEUTICALS (CAYMAN) L.P., ARIAD PHARMACEUTICALS, INC. (AS GUARANTOR), INCYTE CORPORATION (AS GUARANTOR) May 9, 2016

Exhibit 10.2 EXECUTION VERSION SHARE PURCHASE AGREEMENT by and among INCYTE EUROPE S.à r.l., ARIAD PHARMACEUTICALS (CAYMAN) L.P., ARIAD PHARMACEUTICALS, INC. (AS GUARANTOR), and INCYTE CORPORATION (AS GUARANTOR) May 9, 2016 Portions of this Exhibit, indicated by the mark “[***],” were omitted and have been filed separately with the Securities and Exchange Commission pursuant to the Registrant’s ap

August 8, 2016 EX-10.6

Executive Employment Agreement

Exhibit 10.6 Executive Employment Agreement ARIAD Pharmaceuticals, Inc. (the “Company”) a Delaware corporation, and Jayne M. Gansler (the “Employee”) enter into the following Executive Employment Agreement as of the 1st day of June, 2016 (hereafter, the “Agreement”). WHEREAS, the Company wishes to offer the Employee employment according to the following terms and conditions; WHEREAS, the Employee

August 8, 2016 EX-10.5

Executive Employment Agreement

Exhibit 10.5 Executive Employment Agreement ARIAD Pharmaceuticals, Inc. (the “Company”) a Delaware corporation, and Jennifer Herron (the “Employee”) enter into the following Executive Employment Agreement as of the 23rd day of May, 2016 (hereafter, the “Agreement”). WHEREAS, the Company wishes to offer the Employee employment according to the following terms and conditions; WHEREAS, the Employee w

August 8, 2016 EX-10.7

ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN FORM OF OPTION AGREEMENT

Exhibit 10.7 ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN FORM OF OPTION AGREEMENT This Option Agreement certifies that, pursuant to the ARIAD Pharmaceuticals, Inc. 2014 Long-Term Incentive Plan (the “2014 Plan”), the Board of Directors of ARIAD Pharmaceuticals, Inc. (the “Company”) has granted an option (the “Option”) to purchase shares of the Company’s common stock, $.001 par value

July 28, 2016 8-K

ARIAD Pharmaceuticals ARIAD PHARMACEUTICALS, INC. 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 28, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commissi

July 28, 2016 EX-99.1

ARIAD Reports Second Quarter and First Half 2016 Financial Results ~Product revenue of $65.3 million for Q2 2016, including one-time $25.5 million from France ~U.S. product revenue of $32.6 million for Q2 2016, representing 50% growth from prior year

Exhibit 99.1 ARIAD Reports Second Quarter and First Half 2016 Financial Results ~Product revenue of $65.3 million for Q2 2016, including one-time $25.5 million from France ~U.S. product revenue of $32.6 million for Q2 2016, representing 50% growth from prior year ~Conference call scheduled today at 8:30 a.m. ET CAMBRIDGE, Mass.-(BUSINESS WIRE)-July 28, 2016-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARI

July 22, 2016 8-K

ARIAD Pharmaceuticals FORM 8-K (Current Report/Significant Event)

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 21, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation)

July 22, 2016 EX-3.1

CERTIFICATE OF AMENDMENT RESTATED CERTIFICATE OF INCORPORATION ARIAD PHARMACEUTICALS, INC. (Pursuant to Sections 141 and 242 of the General Corporation Law of the State of Delaware)

EX-3.1 Exhibit 3.1 CERTIFICATE OF AMENDMENT OF RESTATED CERTIFICATE OF INCORPORATION OF ARIAD PHARMACEUTICALS, INC. (Pursuant to Sections 141 and 242 of the General Corporation Law of the State of Delaware) ARIAD Pharmaceuticals, Inc., a corporation organized and existing under and by virtue of the provisions of the General Corporation Law of the State of Delaware (the “Delaware General Corporatio

July 19, 2016 EX-24

EX-24

elonakogan15jul16

June 8, 2016 DEFA14A

ARIAD Pharmaceuticals NOTICE AND ACCESS

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

June 8, 2016 DEF 14A

ARIAD Pharmaceuticals DEFINITIVE PROXY STATEMENT

Definitive Proxy Statement Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

June 8, 2016 EX-24

EX-24

jaynegansler

June 7, 2016 EX-99.2

ARIAD PRESENTS DATA FROM MUTATIONAL PROFILING IN CRIZOTINIB-RESISTANT PATIENTS TREATED WITH INVESTIGATIONAL MEDICINE BRIGATINIB SHOWING SIMILAR RESPONSE RATES IN PATIENTS WITH AND WITHOUT SECONDARY ALK MUTATIONS ~ Brigatinib Achieves Confirmed Respon

EX-99.2 Exhibit 99.2 News Release ARIAD PRESENTS DATA FROM MUTATIONAL PROFILING IN CRIZOTINIB-RESISTANT PATIENTS TREATED WITH INVESTIGATIONAL MEDICINE BRIGATINIB SHOWING SIMILAR RESPONSE RATES IN PATIENTS WITH AND WITHOUT SECONDARY ALK MUTATIONS ~ Brigatinib Achieves Confirmed Response in Patient with G1202R Mutation that Emerges Following Treatment with Current Approved Therapies Chicago, IL and

June 7, 2016 EX-99.1

ARIAD PRESENTS LONG-TERM PHASE 1/2 TRIAL FOLLOW UP ON INVESTIGATIONAL DRUG BRIGATINIB WITH MEDIAN TIME ON TREATMENT OF 17 MONTHS IN ALK+ NSCLC PATIENTS ~ Longest Time on Treatment Now More Than 3.5 Years for Patients with ALK+ Non-Small Cell Lung Can

EX-99.1 Exhibit 99.1 News Release ARIAD PRESENTS LONG-TERM PHASE 1/2 TRIAL FOLLOW UP ON INVESTIGATIONAL DRUG BRIGATINIB WITH MEDIAN TIME ON TREATMENT OF 17 MONTHS IN ALK+ NSCLC PATIENTS ~ Longest Time on Treatment Now More Than 3.5 Years for Patients with ALK+ Non-Small Cell Lung Cancer ~ Data from Phase 1/2 Clinical Trial Presented at 2016 ASCO Meeting Chicago, IL and Cambridge, MA ? June 4, 2016

June 7, 2016 8-K

ARIAD Pharmaceuticals 8-K (Current Report/Significant Event)

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 4, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commi

June 7, 2016 EX-99.3

ARIAD’S INVESTIGATIONAL MEDICINE BRIGATINIB DEMONSTRATES 54 PERCENT CONFIRMED OBJECTIVE RESPONSE RATE AND 12.9-MONTH MEDIAN PROGRESSION-FREE SURVIVAL IN ALTA STUDY ~ 67 Percent Confirmed Intracranial Objective Response Rate in Patients with Measurabl

EX-99.3 Exhibit 99.3 News Release FOR IMMEDIATE RELEASE ARIAD?S INVESTIGATIONAL MEDICINE BRIGATINIB DEMONSTRATES 54 PERCENT CONFIRMED OBJECTIVE RESPONSE RATE AND 12.9-MONTH MEDIAN PROGRESSION-FREE SURVIVAL IN ALTA STUDY ~ 67 Percent Confirmed Intracranial Objective Response Rate in Patients with Measurable Brain Metastases ~ Data from Pivotal Study in Refractory ALK Positive Non-Small Cell Lung Ca

June 2, 2016 EX-99.1

ARIAD COMPLETES THE SALE OF ITS EUROPEAN OPERATIONS AND OUT-LICENSE OF EUROPEAN RIGHTS TO ICLUSIG® ~Divestiture to Incyte Strengthens Financial Position ~ARIAD Receives $140 Million Upfront Payment, $135 million to be Received in Potential Oncology M

EX-99.1 Exhibit 99.1 News Release ARIAD COMPLETES THE SALE OF ITS EUROPEAN OPERATIONS AND OUT-LICENSE OF EUROPEAN RIGHTS TO ICLUSIG? ~Divestiture to Incyte Strengthens Financial Position ~ARIAD Receives $140 Million Upfront Payment, $135 million to be Received in Potential Oncology Milestones, Tiered Royalty Payments of Between 32% and 50% Cambridge, MA, June 2, 2016 ? ARIAD Pharmaceuticals, Inc.

June 2, 2016 8-K

ARIAD Pharmaceuticals 8-K (Current Report/Significant Event)

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 1, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation or orga

May 27, 2016 PRE 14A

ARIAD Pharmaceuticals PRELIMINARY PROXY STATEMENT

Preliminary Proxy Statement Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

May 26, 2016 8-K

Current Report

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 23, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commi

May 26, 2016 EX-99.1

ARIAD ANNOUNCES APPOINTMENT OF JENNIFER L. HERRON AS CHIEF COMMERCIAL OFFICER

EX-99.1 Exhibit 99.1 News Release ARIAD ANNOUNCES APPOINTMENT OF JENNIFER L. HERRON AS CHIEF COMMERCIAL OFFICER Cambridge, MA, May 24, 2016?- ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced the appointment of Jennifer L. Herron as executive vice president, chief commercial officer, effective May 31, 2016. She will report to ARIAD?s president and chief executive officer, Paris Panayiotop

May 20, 2016 8-K

ARIAD Pharmaceuticals FORM 8-K (Current Report/Significant Event)

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 19, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (

May 19, 2016 8-K

ARIAD Pharmaceuticals ARIAD PHARMACEUTICALS, INC. 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report: (Date of earliest event reported) May 18, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commissio

May 19, 2016 EX-99.1

ARIAD Announces Data Presentations at the 2016 ASCO Annual Meeting ~Oral Presentation of Clinical Data from ALTA Pivotal Trial on Monday, June 6, 2016 ~ ASCO Presentation to Include Approximately 3 Months of Additional Follow-up Compared to Abstract

Exhibit 99.1 ARIAD Announces Data Presentations at the 2016 ASCO Annual Meeting ~Oral Presentation of Clinical Data from ALTA Pivotal Trial on Monday, June 6, 2016 ~ ASCO Presentation to Include Approximately 3 Months of Additional Follow-up Compared to Abstract ~Investor and Analyst Briefing to be Held at ASCO on Monday, June 6 at 7 a.m. CT CAMBRIDGE, Mass.-(BUSINESS WIRE)-May 18, 2016-ARIAD Phar

May 10, 2016 EX-99.1

ARIAD Reports First Quarter 2016 Financial Results and Progress on Strategic Review ~Recorded Net Product Revenue of $33.6 million for the first quarter of 2016; growth of 41% from prior year ~Provides guidance for 2016, including strengthened year-e

Exhibit 99.1 ARIAD Reports First Quarter 2016 Financial Results and Progress on Strategic Review ~Recorded Net Product Revenue of $33.6 million for the first quarter of 2016; growth of 41% from prior year ~Provides guidance for 2016, including strengthened year-end cash position, following announced Incyte transaction: Global product and royalty revenue of $170 million to $180 million R&D expense

May 10, 2016 8-K

ARIAD Pharmaceuticals ARIAD PHARMACEUTICALS, INC. 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 10, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commissio

May 10, 2016 10-Q

ARIAD Pharmaceuticals 10-Q Q1 2016 (Quarterly Report)

10-Q 1 a2016q110-q.htm 10-Q Q1 2016 Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ý QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2016 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition peri

May 9, 2016 8-K

ARIAD Pharmaceuticals 8-K (Current Report/Significant Event)

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 9, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation or organ

May 9, 2016 EX-99.1

INCYTE AND ARIAD ANNOUNCE AGREEMENT FOR INCYTE TO ACQUIRE ARIAD’S EUROPEAN OPERATIONS AND IN-LICENSE ICLUSIG® IN EUROPE ~Incyte to Accelerate the Expansion of its European Organization to Optimize the Potential of Future Product Launches in Europe ~A

EX-99.1 Exhibit 99.1 FOR IMMEDIATE RELEASE INCYTE AND ARIAD ANNOUNCE AGREEMENT FOR INCYTE TO ACQUIRE ARIAD?S EUROPEAN OPERATIONS AND IN-LICENSE ICLUSIG? IN EUROPE ~Incyte to Accelerate the Expansion of its European Organization to Optimize the Potential of Future Product Launches in Europe ~ARIAD to Receive $140 Million Upfront Payment, Plus Tiered Royalties on European Sales of Iclusig and Potent

May 6, 2016 8-K

ARIAD Pharmaceuticals FORM 8-K (Current Report/Significant Event)

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 4, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (C

May 6, 2016 EX-24

EX-24

bickerstaff

May 6, 2016 EX-24

EX-24

haimovitz

April 29, 2016 EX-4.1

ASSIGNMENT PLEASE INSERT SOCIAL SECURITY OR OTHER IDENTIFYING NUMBER OF ASSIGNEE For value received, hereby sell, assign and transfer unto (PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS, INCLUDING POSTAL ZIP CODE, OF ASSIGNEE) Shares of the common stock

EX-4.1 Exhibit 4.1 THIS CERTIFIES THAT is the owner of CUSIP DATED COUNTERSIGNED AND REGISTERED: COMPUTERSHARE TRUST COMPANY, N.A. TRANSFER AGENT AND REGISTRAR, FULLY PAID AND NON-ASSESSABLE SHARES OF THE COMMON STOCK, $.001 PAR VALUE, OF ARIAD Pharmaceuticals, Inc. transferable only on the books of the Corporation by the holder hereof in person or by duly authorized attorney upon surrender of thi

April 29, 2016 10-K/A

ARIAD Pharmaceuticals FORM 10-K/A (Annual Report)

Form 10-K/A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

April 29, 2016 EX-10.15

Executive Employment Agreement

EX-10.15 Exhibit 10.15 Executive Employment Agreement ARIAD Pharmaceuticals, Inc. (the ?Company?), a Delaware corporation, and Manmeet Singh Soni (the ?Employee?) enter into the following Executive Employment Agreement as of the 9th day of March, 2016 (hereafter, the ?Agreement?). WHEREAS, the Company wishes to offer the Employee employment according to the following terms and conditions; WHEREAS,

April 25, 2016 8-K

Current Report

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 25, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation)

March 29, 2016 8-K

ARIAD Pharmaceuticals FORM 8-K (Current Report/Significant Event)

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 29, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation)

March 29, 2016 EX-99.1

ARIAD ANNOUNCES REDUCTION IN WORKFORCE AS PART OF ONGOING COMPANY-WIDE STRATEGIC REVIEW Approximately 25 percent of its Headquarter Positions to be Impacted

EX-99.1 Exhibit 99.1 News Release FOR IMMEDIATE RELEASE ARIAD ANNOUNCES REDUCTION IN WORKFORCE AS PART OF ONGOING COMPANY-WIDE STRATEGIC REVIEW Approximately 25 percent of its Headquarter Positions to be Impacted Cambridge, MA, March 29, 2016 ? ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that it is reducing approximately 25 percent of its headquarter positions. The reduction include

March 21, 2016 EX-24

EX-24

sonipowerofattord67

March 18, 2016 EX-99.2

FORM OF STOCK OPTION AGREEMENT GOVERNED BY THE TERMS, CONDITIONS AND LIMITATIONS OF THE ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN

EX-99.2 Exhibit 99.2 FORM OF STOCK OPTION AGREEMENT GOVERNED BY THE TERMS, CONDITIONS AND LIMITATIONS OF THE ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN This Stock Option Agreement (this ?Option Agreement?) certifies that the Board of Directors of ARIAD Pharmaceuticals, Inc. (the ?Company?) has granted an option (the ?Option?) to purchase shares of the Company?s common stock, $.001 p

March 18, 2016 EX-99.3

FORM OF 2016 PERFORMANCE SHARE AGREEMENT GOVERNED BY THE TERMS, CONDITIONS AND LIMITATIONS OF THE ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN

EX-99.3 Exhibit 99.3 FORM OF 2016 PERFORMANCE SHARE AGREEMENT GOVERNED BY THE TERMS, CONDITIONS AND LIMITATIONS OF THE ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN This Performance Share Agreement (this “Performance Share Agreement”) certifies that the Board of Directors of ARIAD Pharmaceuticals, Inc. (the “Company”) has granted the Participant the right to receive shares of common st

March 18, 2016 EX-99.1

STOCK OPTION AGREEMENT GOVERNED BY THE TERMS, CONDITIONS AND LIMITATIONS OF THE ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN

EX-99.1 Exhibit 99.1 STOCK OPTION AGREEMENT GOVERNED BY THE TERMS, CONDITIONS AND LIMITATIONS OF THE ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN This Stock Option Agreement (this ?Option Agreement?) certifies that the Board of Directors of ARIAD Pharmaceuticals, Inc. (the ?Company?) has granted an option (the ?Option?) to purchase shares of the Company?s common stock, $.001 par value

March 18, 2016 S-8

ARIAD Pharmaceuticals FORM S-8

FORM S-8 As filed with the Securities and Exchange Commission on March 18, 2016 REGISTRATION NO.

March 18, 2016 EX-10.1

AMENDMENT TO AGREEMENT

Exhibit 10.1 AMENDMENT TO AGREEMENT This AMENDMENT (the ? Amendment?) is made as of March 17, 2016, by and among ARIAD Pharmaceuticals, Inc., a corporation organized and existing under the laws of the State of Delaware (the ? Company?), and the entities listed on Schedule A hereto (collectively, the ? Sarissa Group?). WHEREAS, the Company and the Sarissa Group are parties to that certain Agreement

March 18, 2016 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 17, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commiss

March 18, 2016 SC 13D/A

ARIA / ARIAD Pharmaceuticals, Inc. / Sarissa Capital Management LP - AMENDMENT NO. 7 Activist Investment

SC 13D/A 1 a031816a.htm AMENDMENT NO. 7 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 7)* ARIAD Pharmaceuticals, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 04033A100 (CUSIP Number) Mark DiPaolo General Counsel Sarissa Capital Management LP 660 Steamboat Road, 3rd

March 18, 2016 EX-1

AMENDMENT TO AGREEMENT

AMENDMENT TO AGREEMENT This AMENDMENT (the “Amendment”) is made as of March 17, 2016, by and among ARIAD Pharmaceuticals, Inc.

March 14, 2016 8-K

ARIAD Pharmaceuticals 8-K (Current Report/Significant Event)

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 8, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Comm

March 14, 2016 EX-99.1

ARIAD ANNOUNCES APPOINTMENT OF MANMEET S. SONI AS CHIEF FINANCIAL OFFICER

EX-99.1 Exhibit 99.1 News Release ARIAD ANNOUNCES APPOINTMENT OF MANMEET S. SONI AS CHIEF FINANCIAL OFFICER Cambridge, MA, March 11, 2016?ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced the appointment of Manmeet S. Soni, 38, as executive vice president, chief financial officer and treasurer, effective March 21, 2016. He will report to Paris Panayiotopoulos, president and chief executiv

February 29, 2016 10-K

ARIAD Pharmaceuticals 10-K (Annual Report)

10-K Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

February 29, 2016 EX-21.1

SUBSIDIARIES OF ARIAD PHARMACEUTICALS, INC. Subsidiary Jurisdiction of Organization % Owned ARIAD Pharma S.A. Greece 100 % ARIAD Pharma Ltd. United Kingdom 100 % ARIAD Securities Corporation Massachusetts, United States 100 % ARIAD Pharmaceuticals (C

EX-21.1 Exhibit 21.1 SUBSIDIARIES OF ARIAD PHARMACEUTICALS, INC. Subsidiary Jurisdiction of Organization % Owned ARIAD Pharma S.A. Greece 100 % ARIAD Pharma Ltd. United Kingdom 100 % ARIAD Securities Corporation Massachusetts, United States 100 % ARIAD Pharmaceuticals (Cayman) Inc. Cayman Islands 100 % ARIAD Pharmaceuticals (Cayman) L.P. Cayman Islands 99.9999 %* ARIAD Pharmaceuticals (Japan) GK J

February 29, 2016 EX-4.1

ASSIGNMENT PLEASE INSERT SOCIAL SECURITY OR OTHER IDENTIFYING NUMBER OF ASSIGNEE For value received, hereby sell, assign and transfer unto

EX-4.1 Exhibit 4.1 . ZQ|CERT#|COY|CLS|RGSTRY|ACCT#|TRANSTYPE|RUN#|TRANS# COMMON STOCK PAR VALUE $.001 ARIAD COMMON STOCK THIS CERTIFICATE IS TRANSFERABLE IN CANTON, MA, JERSEY CITY, NJ AND COLLEGE STATION, TX Certificate Number ZQ00000000 THIS CERTIFIES THAT ARIAD PHARMACEUTICALS, INC. INCORPORATED UNDER THE LAWS OF THE STATE OF DELAWARE MR. SAMPLE & MRS. SAMPLE & MR. SAMPLE & MRS. SAMPLE ** Mr. A

February 23, 2016 EX-99.1

ARIAD Reports 2015 Financial Results, Provides 2016 Product Revenue Guidance and Outlines Company Progress Iclusig Net Product Revenue Guidance for 2016 in the Range of $190 Million to $200 Million Filing for U.S. Marketing Approval of Brigatinib Exp

Exhibit 99.1 ARIAD Reports 2015 Financial Results, Provides 2016 Product Revenue Guidance and Outlines Company Progress Iclusig Net Product Revenue Guidance for 2016 in the Range of $190 Million to $200 Million Filing for U.S. Marketing Approval of Brigatinib Expected This Year Conference Call Scheduled Today at 8:30 a.m. ET CAMBRIDGE, Mass.-(BUSINESS WIRE)-February 23, 2016-ARIAD Pharmaceuticals,

February 23, 2016 8-K

Regulation FD Disclosure, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 23, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Comm

February 10, 2016 SC 13G/A

ARIAD Pharmaceuticals 3G/A (Passive Acquisition of More Than 5% of Shares)

ariadpharmaceuticalsinc.htm - Generated by SEC Publisher for SEC Filing SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 3 )* Name of issuer: ARIAD Pharmaceuticals Inc Title of Class of Securities: Common Stock CUSIP Number: 04033A100 Date of Event Which Requires Filing of this Statement: December 31, 2015 Check the ap

February 10, 2016 SC 13G

ARIA / ARIAD Pharmaceuticals, Inc. / WESTFIELD CAPITAL MANAGEMENT CO LP - WESTFIELD CAPITAL MANAGEMENT COMPANY, L.P. Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Ariad Pharmaceuticals, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 04033A100 (CUSIP Number) December 31, 2015 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is fi

January 13, 2016 EX-3.3

CERTIFICATE OF ELIMINATION SERIES C CONVERTIBLE PREFERRED STOCK ARIAD PHARMACEUTICALS, INC. Pursuant to Section 151 of the General Corporation Law of the State of Delaware

EX-3.3 Exhibit 3.3 CERTIFICATE OF ELIMINATION OF SERIES C CONVERTIBLE PREFERRED STOCK OF ARIAD PHARMACEUTICALS, INC. Pursuant to Section 151 of the General Corporation Law of the State of Delaware ARIAD PHARMACEUTICALS, INC., a corporation organized and existing under the laws of the State of Delaware (the ?Company?), DOES HEREBY CERTIFY: First: Pursuant to Section 151 of the General Corporation L

January 13, 2016 EX-3.2

CERTIFICATE OF ELIMINATION SERIES B CONVERTIBLE PREFERRED STOCK ARIAD PHARMACEUTICALS, INC. Pursuant to Section 151 of the General Corporation Law of the State of Delaware

EX-3.2 Exhibit 3.2 CERTIFICATE OF ELIMINATION OF SERIES B CONVERTIBLE PREFERRED STOCK OF ARIAD PHARMACEUTICALS, INC. Pursuant to Section 151 of the General Corporation Law of the State of Delaware ARIAD PHARMACEUTICALS, INC., a corporation organized and existing under the laws of the State of Delaware (the ?Company?), DOES HEREBY CERTIFY: First: Pursuant to Section 151 of the General Corporation L

January 13, 2016 8-K

ARIAD Pharmaceuticals 8-K (Current Report/Significant Event)

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 8, 2016 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Co

January 13, 2016 EX-99.1

Building Shareholder Value January 2016 J. P. Morgan Health care Conference A R I A D Pharmaceuticals , Inc . David Sachs Non-small cell lung cancer ARIAD clinical trial patient

EX-99.1 Exhibit 99.1 Building Shareholder Value January 2016 J. P. Morgan Health care Conference A R I A D Pharmaceuticals , Inc . David Sachs Non-small cell lung cancer ARIAD clinical trial patient Some of the statements in this presentation constitute ?forward looking statements? under the Private Securities Litigation Reform Act of 1995. Such statements are subject to factors, risks and uncerta

January 13, 2016 EX-99.2

ARIAD ANNOUNCES ELECTION OF ALEX DENNER AS CHAIRMAN OF THE BOARD OF DIRECTORS

EX-99.2 Exhibit 99.2 News Release ARIAD ANNOUNCES ELECTION OF ALEX DENNER AS CHAIRMAN OF THE BOARD OF DIRECTORS Cambridge, MA ? January 10, 2016 ? ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced the election of Alexander J. Denner, Ph.D., as chairman of its board of directors in a unanimous vote effective January 8, 2016. Dr. Denner joined the ARIAD Board of Directors in February 2014 a

January 13, 2016 EX-3.1

CERTIFICATE OF ELIMINATION SERIES A JUNIOR PARTICIPATING PREFERRED STOCK ARIAD PHARMACEUTICALS, INC. Pursuant to Section 151 of the General Corporation Law of the State of Delaware

EX-3.1 Exhibit 3.1 CERTIFICATE OF ELIMINATION OF SERIES A JUNIOR PARTICIPATING PREFERRED STOCK OF ARIAD PHARMACEUTICALS, INC. Pursuant to Section 151 of the General Corporation Law of the State of Delaware ARIAD PHARMACEUTICALS, INC., a corporation organized and existing under the laws of the State of Delaware (the ?Company?) DOES HEREBY CERTIFY: First: Pursuant to Section 151 of the General Corpo

January 13, 2016 8-A12B/A

ARIAD Pharmaceuticals 8-A12B/A

8-A12B/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-A/A (Amendment No. 3) FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 22-3106987 (State or other jurisdiction of incorporation) (IRS Employer Iden

January 13, 2016 EX-99.3

ARIAD ANNOUNCES TERMINATION OF SHAREHOLDER RIGHTS PLAN

EX-99.3 Exhibit 99.3 News Release ARIAD ANNOUNCES TERMINATION OF SHAREHOLDER RIGHTS PLAN Cambridge, MA, January 11, 2016?- ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that its Board of Directors has unanimously approved the termination of the Company?s Section 382 Rights Agreement, or the Rights Plan, originally adopted on October 31, 2013, effective immediately. The Rights Plan and

January 13, 2016 EX-3.4

RESTATED CERTIFICATE OF INCORPORATION ARIAD PHARMACEUTICALS, INC. (Pursuant to Sections 141 and 245 of the General Corporation Law of the State of Delaware)

EX-3.4 Exhibit 3.4 RESTATED CERTIFICATE OF INCORPORATION OF ARIAD PHARMACEUTICALS, INC. (Pursuant to Sections 141 and 245 of the General Corporation Law of the State of Delaware) ARIAD Pharmaceuticals, Inc., a corporation organized and existing under and by virtue of the provisions of the General Corporation Law of the State of Delaware (the ?Delaware General Corporation Law?), DOES HEREBY CERTIFY

January 13, 2016 EX-4.1

[Remainder of page intentionally left blank]

EX-4.1 Exhibit 4.1 SECOND AMENDMENT dated as of January 8, 2016 (this ?Amendment?), to the SECTION 382 RIGHTS AGREEMENT dated as of October 31, 2013, as amended as of June 24, 2014 (as so amended and in effect from the date hereof, the ?Rights Agreement?), between ARIAD PHARMACEUTICALS, INC., a Delaware corporation (the ?Company?), and COMPUTERSHARE TRUST COMPANY, N.A., as Rights Agent (the ?Right

December 18, 2015 EX-99.1

ARIAD NAMES PARIS PANAYIOTOPOULOS AS ITS PRESIDENT AND CHIEF EXECUTIVE OFFICER

Exhibit 99.1 News Release ARIAD NAMES PARIS PANAYIOTOPOULOS AS ITS PRESIDENT AND CHIEF EXECUTIVE OFFICER Cambridge, MA, December 18, 2015 ?- ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that its Board of Directors has voted unanimously to appoint Paris Panayiotopoulos President and Chief Executive Officer (CEO), effective January 1, 2016. Panayiotopoulos joins ARIAD from his current

December 18, 2015 EX-10.1

Executive Employment Agreement

Exhibit 10.1 Executive Employment Agreement ARIAD Pharmaceuticals, Inc. (the “ Company”), a Delaware corporation, and Paris Panayiotopoulos (the “ Employee”), an individual, enter into this Executive Employment Agreement as of December 16, 2015 (the “ Agreement”). WHEREAS, the Company wishes to offer the Employee employment according to the following terms and conditions; and WHEREAS, the Employee

December 18, 2015 EX-10.2

FORM OF RESTRICTED STOCK UNIT AGREEMENT GOVERNED BY THE TERMS, CONDITIONS AND LIMITATIONS OF THE ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN

Exhibit 10.2 FORM OF RESTRICTED STOCK UNIT AGREEMENT GOVERNED BY THE TERMS, CONDITIONS AND LIMITATIONS OF THE ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN This Restricted Stock Unit Agreement (this ? Restricted Stock Unit Agreement?) certifies that the Board of Directors of ARIAD Pharmaceuticals, Inc. (the ? Company ?) has granted an unvested right to receive shares of Common Stock, $

December 18, 2015 EX-10.3

FORM OF STOCK OPTION AGREEMENT GOVERNED BY THE TERMS, CONDITIONS AND LIMITATIONS OF THE ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN

Exhibit 10.3 FORM OF STOCK OPTION AGREEMENT GOVERNED BY THE TERMS, CONDITIONS AND LIMITATIONS OF THE ARIAD PHARMACEUTICALS, INC. 2014 LONG-TERM INCENTIVE PLAN This Stock Option Agreement (this ? Option Agreement?) certifies that the Board of Directors of ARIAD Pharmaceuticals, Inc. (the ? Company ?) has granted an option (the ? Option ?) to purchase shares of the Company ?s common stock, $.001 par

December 18, 2015 8-K

ARIAD Pharmaceuticals (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 16, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Comm

November 3, 2015 EX-99.1

ARIAD REPORTS THIRD QUARTER 2015 FINANCIAL RESULTS AND PROGRESS ON STRATEGIC OBJECTIVES Conference Call Scheduled Today at 8:30 a.m. ET

EX-99.1 Exhibit 99.1 News Release ARIAD REPORTS THIRD QUARTER 2015 FINANCIAL RESULTS AND PROGRESS ON STRATEGIC OBJECTIVES Conference Call Scheduled Today at 8:30 a.m. ET Cambridge, MA, November 3, 2015–- ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today reported financial results for the third quarter of 2015, including revenue from sales of Iclusig® (ponatinib). The Company also provided an update

November 3, 2015 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

8-K 1 d73398d8k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 3, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction

September 11, 2015 8-K

ARIAD Pharmaceuticals CURRENT REPORT (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 9, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Comm

August 21, 2015 8-K

ARIAD Pharmaceuticals 8-K (Current Report/Significant Event)

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 20, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Co

August 5, 2015 8-K

ARIAD Pharmaceuticals FORM 8-K (Current Report/Significant Event)

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 5, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation)

August 5, 2015 EX-99.1

ARIAD REPORTS SECOND QUARTER 2015 FINANCIAL RESULTS AND PROGRESS ON STRATEGIC OBJECTIVES Conference Call Scheduled Today at 8:30 a.m. ET

EX-99.1 Exhibit 99.1 News Release ARIAD REPORTS SECOND QUARTER 2015 FINANCIAL RESULTS AND PROGRESS ON STRATEGIC OBJECTIVES Conference Call Scheduled Today at 8:30 a.m. ET Cambridge, MA, August 5, 2015? ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today reported financial results for the second quarter of 2015, including revenue from sales of Iclusig? (ponatinib). The Company also provided an update

July 29, 2015 EX-99.1

ARIAD TO RECEIVE UP TO $200 MILLION THROUGH ICLUSIG NON-DILUTIVE SYNTHETIC-ROYALTY FINANCING WITH PDL BIOPHARMA Funding to support initiation of first-line study of brigatinib in ALK+ NSCLC and commercial launch readiness for brigatinib

EX-99.1 Exhibit 99.1 News Release ARIAD TO RECEIVE UP TO $200 MILLION THROUGH ICLUSIG NON-DILUTIVE SYNTHETIC-ROYALTY FINANCING WITH PDL BIOPHARMA Funding to support initiation of first-line study of brigatinib in ALK+ NSCLC and commercial launch readiness for brigatinib Cambridge, MA ? July 29, 2015 ? ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that it will receive $100 million in c

July 29, 2015 8-K

ARIAD Pharmaceuticals FORM 8-K (Current Report/Significant Event)

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 28, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation)

July 27, 2015 8-K

ARIAD Pharmaceuticals CURRENT REPORT (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 21 , 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commiss

July 24, 2015 8-K

Current Report

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 23, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation)

June 25, 2015 DEF 14A

ARIAD Pharmaceuticals DEF 14A

DEF 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

May 7, 2015 EX-99.1

ARIAD REPORTS FIRST QUARTER 2015 FINANCIAL RESULTS AND PROGRESS ON STRATEGIC OBJECTIVES Conference Call Scheduled Today at 8:30 a.m. ET

EX-99.1 Exhibit 99.1 News Release ARIAD REPORTS FIRST QUARTER 2015 FINANCIAL RESULTS AND PROGRESS ON STRATEGIC OBJECTIVES Conference Call Scheduled Today at 8:30 a.m. ET Cambridge, MA, May 7, 2015? ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today reported financial results for the first quarter of 2015, including revenue from sales of Iclusig? (ponatinib). The Company also provided an update on co

May 7, 2015 8-K

ARIAD Pharmaceuticals 8-K (Current Report/Significant Event)

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commis

April 29, 2015 SC 13D/A

ARIA / ARIAD Pharmaceuticals, Inc. / Sarissa Capital Management LP - SCHEDULE 13D/A, #6 Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 6)* ARIAD Pharmaceuticals, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 04033A100 (CUSIP Number) Mark DiPaolo General Counsel Sarissa Capital Management LP 660 Steamboat Road, 3rd Floor Greenwich, CT 06830 203-302-2330

April 29, 2015 8-K

ARIAD Pharmaceuticals CURRENT REPORT (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 28, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commiss

April 29, 2015 EX-10.1

[Remainder of Page Intentionally Left Blank]

Exhibit 10.1 AGREEMENT This AGREEMENT (the ? Agreement?) is made as of April 28, 2015 by and among ARIAD Pharmaceuticals, Inc., a corporation organized and existing under the laws of the State of Delaware (the ? Company?), and the persons and entities listed on Schedule A hereto (collectively, the ? Sarissa Group?). In consideration of the covenants and promises set forth herein, and for other goo

April 29, 2015 DEFA14A

ARIAD Pharmaceuticals CURRENT REPORT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 28, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commiss

April 29, 2015 EX-10.2

[Remainder of page intentionally left blank.]

Exhibit 10.2 April 28, 2015 Harvey J. Berger, M.D. ARIAD Pharmaceuticals, Inc. 26 Landsdowne Street Cambridge, MA 02139-4234 Re: Retirement Agreement Dear Harvey: This retirement letter agreement (this ? Agreement?) is intended to amend the Amended and Restated Employment Agreement by and between you and ARIAD Pharmaceuticals, Inc. (the ? Company?), dated as of April 30, 2010 (the ? Employment Agr

April 29, 2015 EX-99.1

ARIAD Enters into Settlement Agreement with Sarissa Capital Management

Exhibit 99.1 ARIAD Enters into Settlement Agreement with Sarissa Capital Management CAMBRIDGE, Mass.-(BUSINESS WIRE)-Apr. 29, 2015 - ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that it has reached an agreement to settle its current proxy contest with Sarissa Capital Management. In addition, ARIAD’s founder, Harvey J. Berger, M.D., has informed the Board of Directors of his decision

April 29, 2015 EX-99.1

ARIAD Enters into Settlement Agreement with Sarissa Capital Management

Exhibit 99.1 ARIAD Enters into Settlement Agreement with Sarissa Capital Management CAMBRIDGE, Mass.-(BUSINESS WIRE)-Apr. 29, 2015 - ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that it has reached an agreement to settle its current proxy contest with Sarissa Capital Management. In addition, ARIAD?s founder, Harvey J. Berger, M.D., has informed the Board of Directors of his decision

April 29, 2015 EX-99.2

ARIAD Founder, Harvey J. Berger, M.D., to Retire as Chairman and Chief Executive Officer

Exhibit 99.2 ARIAD Founder, Harvey J. Berger, M.D., to Retire as Chairman and Chief Executive Officer CAMBRIDGE, Mass-(BUSINESS WIRE)-Apr. 29, 2015 - ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that its founder, Harvey J. Berger, M.D., has informed the Board of his decision to retire as chairman and chief executive officer (CEO) upon the appointment of his successor or December 31,

April 29, 2015 EX-99.2

ARIAD Founder, Harvey J. Berger, M.D., to Retire as Chairman and Chief Executive Officer

Exhibit 99.2 ARIAD Founder, Harvey J. Berger, M.D., to Retire as Chairman and Chief Executive Officer CAMBRIDGE, Mass-(BUSINESS WIRE)-Apr. 29, 2015 - ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that its founder, Harvey J. Berger, M.D., has informed the Board of his decision to retire as chairman and chief executive officer (CEO) upon the appointment of his successor or December 31,

April 29, 2015 EX-99.1

[Remainder of Page Intentionally Left Blank]

Exhibit 99.1 AGREEMENT This AGREEMENT (the “Agreement”) is made as of April 28, 2015 by and among ARIAD Pharmaceuticals, Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”), and the persons and entities listed on Schedule A hereto (collectively, the “Sarissa Group”). In consideration of the covenants and promises set forth herein, and for other good a

April 29, 2015 EX-10.2

[Remainder of page intentionally left blank.]

Exhibit 10.2 April 28, 2015 Harvey J. Berger, M.D. ARIAD Pharmaceuticals, Inc. 26 Landsdowne Street Cambridge, MA 02139-4234 Re: Retirement Agreement Dear Harvey: This retirement letter agreement (this ? Agreement?) is intended to amend the Amended and Restated Employment Agreement by and between you and ARIAD Pharmaceuticals, Inc. (the ? Company?), dated as of April 30, 2010 (the ? Employment Agr

April 29, 2015 EX-10.1

[Remainder of Page Intentionally Left Blank]

Exhibit 10.1 AGREEMENT This AGREEMENT (the ? Agreement?) is made as of April 28, 2015 by and among ARIAD Pharmaceuticals, Inc., a corporation organized and existing under the laws of the State of Delaware (the ? Company?), and the persons and entities listed on Schedule A hereto (collectively, the ? Sarissa Group?). In consideration of the covenants and promises set forth herein, and for other goo

March 25, 2015 EX-99.1

ARIAD ANNOUNCES DISMISSAL OF SHAREHOLDER CLASS ACTION LAWSUIT IN FEDERAL DISTRICT COURT

EX-99.1 Exhibit 99.1 News Release ARIAD ANNOUNCES DISMISSAL OF SHAREHOLDER CLASS ACTION LAWSUIT IN FEDERAL DISTRICT COURT Cambridge, MA. ? March 25, 2015 ? ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that the United States District Court for the District of Massachusetts dismissed the shareholder class action lawsuit filed in late 2013 against the Company and certain of its officers

March 25, 2015 8-K

ARIAD Pharmaceuticals FORM 8-K (Current Report/Significant Event)

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 25, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation)

March 13, 2015 EX-99.1

ARIAD Announces Dismissal of Shareholder Derivative Lawsuit in Federal District Court

Exhibit 99.1 ARIAD Announces Dismissal of Shareholder Derivative Lawsuit in Federal District Court CAMBRIDGE, Mass.-(BUSINESS WIRE)-March 10, 2015-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) announced today that the United States District Court for the District of Massachusetts dismissed the shareholder derivative lawsuit filed in late 2013 against the Company and certain of its officers and direct

March 13, 2015 8-K

ARIAD Pharmaceuticals ARIAD PHARMACEUTICALS, INC. 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commiss

February 26, 2015 DEFA14A

ARIA / ARIAD Pharmaceuticals, Inc. DEFA14A - - SCHEDULE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Defin

February 25, 2015 SC 13D/A

ARIA / ARIAD Pharmaceuticals, Inc. / Sarissa Capital Management LP - AMENDMENT NO. 5 Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 5)* ARIAD Pharmaceuticals, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 04033A100 (CUSIP Number) Mark DiPaolo General Counsel Sarissa Capital Management LP 660 Steamboat Road, 3rd Floor Greenwich, CT 06830 203-302-2330

February 20, 2015 SC 13D/A

ARIA / ARIAD Pharmaceuticals, Inc. / Sarissa Capital Management LP - AMENDMENT NO. 4 Activist Investment

SC 13D/A 1 a021315.htm AMENDMENT NO. 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 4)* ARIAD Pharmaceuticals, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 04033A100 (CUSIP Number) Mark DiPaolo General Counsel Sarissa Capital Management LP 660 Steamboat Road, 3rd

February 19, 2015 8-K

Regulation FD Disclosure, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 19, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Comm

February 19, 2015 EX-99.1

ARIAD Reports 2014 Financial Results, Provides 2015 Financial Guidance and Outlines Strategic Objectives Iclusig Net Product Revenue Guidance for 2015 in the Range of $130 Million to $140 Million Three New Iclusig Clinical Trials Planned to Begin Thi

Exhibit 99.1 ARIAD Reports 2014 Financial Results, Provides 2015 Financial Guidance and Outlines Strategic Objectives Iclusig Net Product Revenue Guidance for 2015 in the Range of $130 Million to $140 Million Three New Iclusig Clinical Trials Planned to Begin This Year CAMBRIDGE, Mass.-(BUSINESS WIRE)-February 19, 2015-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today reported financial results for

February 17, 2015 SC 13G/A

ARIA / ARIAD Pharmaceuticals, Inc. / Adage Capital Partners GP LLC - ARIAD PHARMACEUTICALS, INC. Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1 )* ARIAD Pharmaceuticals, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 04033A100 (CUSIP Number) December 31, 2014 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule p

February 10, 2015 SC 13G/A

ARIA / ARIAD Pharmaceuticals, Inc. / VANGUARD GROUP INC Passive Investment

ariadpharmainc.htm - Generated by SEC Publisher for SEC Filing SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 2 )* Name of issuer: ARIAD Pharmaceuticals Inc Title of Class of Securities: Common Stock CUSIP Number: 04033A100 Date of Event Which Requires Filing of this Statement: December 31, 2014 Check the appropriate

January 14, 2015 EX-99.2

Path to Value and Profitability Elsa So Non-small cell lung cancer ARIAD clinical trial patient Harvey J. Berger M.D. Chairman and Chief Executive Officer ARIAD Pharmaceuticals, Inc.

Exhibit 99.2 Path to Value and Profitability Elsa So Non-small cell lung cancer ARIAD clinical trial patient Harvey J. Berger M.D. Chairman and Chief Executive Officer ARIAD Pharmaceuticals, Inc. 01.14.2015 J.P. Morgan Healthcare Conference Some of the statements in this presentation constitute “forward looking statements” under the Private Securities Litigation Reform Act of 1995. Such statements

January 14, 2015 EX-99.1

ARIAD Announces Key Strategic Objectives for 2015 Expected to Lead Company to Profitability in Three Years Iclusig Commercial Opportunity Expected to Expand -- Three New Clinical Trials to Begin in 2015, including a Global, Randomized Trial of Iclusi

Exhibit 99.1 ARIAD Announces Key Strategic Objectives for 2015 Expected to Lead Company to Profitability in Three Years Iclusig Commercial Opportunity Expected to Expand - Three New Clinical Trials to Begin in 2015, including a Global, Randomized Trial of Iclusig vs. Nilotinib in Second-Line CML CAMBRIDGE, Mass.-(BUSINESS WIRE)-January 13, 2015-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today anno

January 14, 2015 8-K

Regulation FD Disclosure, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commi

January 7, 2015 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 6, 2015 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commis

January 7, 2015 EX-99.1

ARIAD Announces Phase 2 Dose-Ranging Trial of Iclusig (Ponatinib) to Begin by Mid-2015 Randomized Global Trial to Evaluate Safety and Efficacy of Iclusig at Three Starting Doses

Exhibit 99.1 ARIAD Announces Phase 2 Dose-Ranging Trial of Iclusig (Ponatinib) to Begin by Mid-2015 Randomized Global Trial to Evaluate Safety and Efficacy of Iclusig at Three Starting Doses CAMBRIDGE, Mass.-(BUSINESS WIRE)-January 6, 2015-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that it has concluded consultations with U.S. and European health authorities regarding the design of

December 30, 2014 8-K

Current Report

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 22, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (

December 30, 2014 8-K

Current Report

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 29, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (

December 30, 2014 EX-99.1

ARIAD AND OTSUKA ANNOUNCE CO-DEVELOPMENT AND COMMERCIALIZATION AGREEMENT FOR ICLUSIG® TO TREAT LEUKEMIAS IN JAPAN AND NINE OTHER ASIAN COUNTRIES

EX-99.1 Exhibit 99.1 News Release ARIAD AND OTSUKA ANNOUNCE CO-DEVELOPMENT AND COMMERCIALIZATION AGREEMENT FOR ICLUSIG® TO TREAT LEUKEMIAS IN JAPAN AND NINE OTHER ASIAN COUNTRIES • ARIAD to receive upfront payment of USD 77.5 million and subsequent milestone-based payments • Otsuka to obtain rights in ten Asian countries to Iclusig, a newest-generation treatment for patients with refractory chroni

December 11, 2014 EX-99.1

ARIAD Announces Long-Term Safety and Efficacy Data of Ponatinib from Phase 2 Pace Clinical Trial

Exhibit 99.1 ARIAD Announces Long-Term Safety and Efficacy Data of Ponatinib from Phase 2 Pace Clinical Trial SAN FRANCISCO & CAMBRIDGE, Mass.-(BUSINESS WIRE)-December 8, 2014-ARIAD Pharmaceuticals, Inc. (NASDAQ:ARIA) today announced long-term follow up from its pivotal Phase 2 trial of Iclusig® (ponatinib), its approved BCR-ABL inhibitor, in heavily pretreated patients with resistant or intoleran

December 11, 2014 EX-99.2

ARIAD Announces Long-Term Safety and Efficacy Data of Ponatinib in Chronic-Phase Chronic Myeloid Leukemia from Phase 1 Clinical Trial ~ Median Follow-up in Trial Now Four Years

Exhibit 99.2 ARIAD Announces Long-Term Safety and Efficacy Data of Ponatinib in Chronic-Phase Chronic Myeloid Leukemia from Phase 1 Clinical Trial ~ Median Follow-up in Trial Now Four Years CAMBRIDGE, Mass. & SAN FRANCISCO-(BUSINESS WIRE)-December 9, 2014-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced long-term follow up data from the Phase 1 trial of Iclusig® (ponatinib), its approved

December 11, 2014 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 8, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commi

December 11, 2014 EX-99.3

ARIAD Announces Follow-up Data from Phase 1 and PACE Trials of Ponatinib in Patients with T315I Mutation in Chronic Myeloid Leukemia

Exhibit 99.3 ARIAD Announces Follow-up Data from Phase 1 and PACE Trials of Ponatinib in Patients with T315I Mutation in Chronic Myeloid Leukemia CAMBRIDGE, Mass. & SAN FRANCISCO-(BUSINESS WIRE)-December 9, 2014-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced safety and efficacy follow-up data on Iclusig® (ponatinib), its approved BCR-ABL inhibitor, in patients with a baseline T315I mut

November 6, 2014 CORRESP

ARIA / ARIAD Pharmaceuticals, Inc. CORRESP - -

CORRESP November 6, 2014 VIA EDGAR AND OVERNIGHT MAIL United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

November 5, 2014 8-K

Regulation FD Disclosure, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 5, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commi

November 5, 2014 EX-99.1

ARIAD Reports Third Quarter 2014 Financial Results and Development Progress Conference Call Scheduled Today at 8:30 a.m. ET

Exhibit 99.1 ARIAD Reports Third Quarter 2014 Financial Results and Development Progress Conference Call Scheduled Today at 8:30 a.m. ET CAMBRIDGE, Mass.-(BUSINESS WIRE)-November 5, 2014-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today reported financial results for the third quarter of 2014, including revenue from sales of Iclusig® (ponatinib). The Company also provided an update on corporate dev

October 28, 2014 CORRESP

ARIA / ARIAD Pharmaceuticals, Inc. CORRESP - -

Correspondence October 28, 2014 VIA EDGAR AND OVERNIGHT MAIL United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

October 24, 2014 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 24, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commi

October 24, 2014 EX-99.1

ARIAD Announces Adoption of Final Opinion for Iclusig by Committee for Medicinal Products for Human Use in Europe

Exhibit 99.1 ARIAD Announces Adoption of Final Opinion for Iclusig by Committee for Medicinal Products for Human Use in Europe CAMBRIDGE, Mass. & LAUSANNE, Switzerland-(BUSINESS WIRE)-October 24, 2014-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted its final opinion on Iclus

October 10, 2014 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 3, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 0-36172 22-3106987 (State or other jurisdiction of incorporation) (Commissi

October 10, 2014 EX-99.1

ARIAD and Bellicum Announce Revised License Agreement for ARIAD’s Cell-Signaling Technology

Exhibit 99.1 ARIAD and Bellicum Announce Revised License Agreement for ARIAD’s Cell-Signaling Technology CAMBRIDGE, Mass. & HOUSTON-(BUSINESS WIRE)-October 6, 2014-ARIAD Pharmaceuticals, Inc. (NASDAQ:ARIA) and Bellicum Pharmaceuticals, Inc. today announced a restructuring of their license agreement for ARIAD’s cell-signaling technology. ARIAD will receive $50 million in exchange for a fully paid u

September 29, 2014 EX-99.1

ARIAD Presents Updated Clinical Data on AP26113 in Patients with ALK+ Non-Small Cell Lung Cancer

Exhibit 99.1 ARIAD Presents Updated Clinical Data on AP26113 in Patients with ALK+ Non-Small Cell Lung Cancer MADRID & CAMBRIDGE, Mass.-(BUSINESS WIRE)-September 29, 2014-ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced updated clinical results on its investigational tyrosine kinase inhibitor (TKI), AP26113, in patients with advanced non-small cell lung cancer (NSCLC) from an ongoing Pha

September 29, 2014 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 27, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Com

September 18, 2014 8-K

Current Report

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 13, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporat

September 5, 2014 S-8 POS

ARIA / ARIAD Pharmaceuticals, Inc. S-8 POS - - S-8 POS

S-8 POS As filed with the Securities and Exchange Commission on September 5, 2014 REGISTRATION NO.

September 5, 2014 S-8

ARIA / ARIAD Pharmaceuticals, Inc. S-8 - - FORM S-8

Form S-8 As filed with the Securities and Exchange Commission on September 5, 2014 REGISTRATION NO.

September 2, 2014 SC 13D/A

ARIA / ARIAD Pharmaceuticals, Inc. / Sarissa Capital Management LP - AMENDMENT NO. 3 Activist Investment

SC 13D/A 1 a082814.htm AMENDMENT NO. 3 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 3)* ARIAD Pharmaceuticals, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 04033A100 (CUSIP Number) Mark DiPaolo General Counsel Sarissa Capital Management LP 660 Steamboat Road, 3rd

August 27, 2014 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 26, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction (Commission (I.R.S. Emplo

August 27, 2014 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 26, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction (Commission (I.R.S. Emplo

August 27, 2014 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 19, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commis

August 20, 2014 SC 13D/A

ARIA / ARIAD Pharmaceuticals, Inc. / Sarissa Capital Management LP - SCHEDULE 13D/A, AMENDMENT #2 Activist Investment

SC 13D/A 1 s13da2.htm SCHEDULE 13D/A, AMENDMENT #2 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 2)* ARIAD Pharmaceuticals, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 04033A100 (CUSIP Number) Mark DiPaolo General Counsel Sarissa Capital Management LP 660 Steamboa

August 8, 2014 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commiss

August 6, 2014 8-K

Regulation FD Disclosure, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 6, 2014 ARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36172 22-3106987 (State or other jurisdiction of incorporation) (Commiss

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