Market Value259,631,000
Total Holdings452
File Date2020-10-26
Original Filing (Click here)

All hedge funds or institutions that manage over $100M are required by the SEC to file quarterly reports on their holdings. These reports are called 13F reports. However, the filings are required the following quarter from the reporting period, which means that by the time the filing is made (and we see them), the information could be five months old.

For funds with long term positions that make few trades, the holdings might closely resemble their current holdings, even after several months. However, for funds that have high turnover, the holdings data we see might differ significantly from their current holdings. Institutions are required to report CALL and PUT options, and those positions are identified in the table. However, they are not required to report short positions.

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Security Imputed
Share Price
Prev
Shares
Current
Shares
Change
(Percent)
Prev Value
(USD x1000)
Current Value
(USD x1000)
Change
(Percent)
LIT / Global X Funds - Global X Lithium & Battery Tech ETF
GDXJ / VanEck ETF Trust - VanEck Junior Gold Miners ETF
RSPH / Invesco Exchange-Traded Fund Trust - Invesco S&P 500 Equal Weight Health Care ETF
LEVI / Levi Strauss & Co.
TNDM / Tandem Diabetes Care, Inc.
QMCO / Quantum Corporation
D / Dominion Energy, Inc.
MRVL / Marvell Technology, Inc.
KEY / KeyCorp
C / Citigroup Inc.
WAB / Westinghouse Air Brake Technologies Corporation
ADBE / Adobe Inc.
A / Agilent Technologies, Inc.
BTT / Blackrock Municipal 2030 Target Term Trust
AYX / Alteryx, Inc.
WYNN / Wynn Resorts, Limited
GWP / GW Pharmaceuticals plc
VBR / Vanguard Index Funds - Vanguard Small-Cap Value ETF
VZ / Verizon Communications Inc.
LVS / Las Vegas Sands Corp.
RCL / Royal Caribbean Cruises Ltd.
SEIC / SEI Investments Company
CE / Celanese Corporation
BKNG / Booking Holdings Inc.
LRCX / Lam Research Corporation
TSLA / Tesla, Inc.
PFIS / Peoples Financial Services Corp.
FITB / Fifth Third Bancorp
AXP / American Express Company
KODK / Eastman Kodak Company
RPRX / Royalty Pharma plc
SMB / VanEck ETF Trust - VanEck Short Muni ETF
AAPL / Apple Inc.
904784709 / Unilever N.V.
US67061Q1076 / Nuveen Maryland Quality Muncpl Incm Fund
LARK / Landmark Bancorp, Inc.
FFIV / F5, Inc.
HAL / Halliburton Company
DG / Dollar General Corporation
ICUI / ICU Medical, Inc.
UA / Under Armour, Inc.
UAL / United Airlines Holdings, Inc.
HIG / The Hartford Insurance Group, Inc.
JMST / J.P. Morgan Exchange-Traded Fund Trust - JPMorgan Ultra-Short Municipal Income ETF
TWLO / Twilio Inc.
NLY / Annaly Capital Management, Inc.
MAIN / Main Street Capital Corporation
EXPE / Expedia Group, Inc.
COOP / Mr. Cooper Group Inc.
GPS / The Gap, Inc.
TWTR / Twitter Inc
LPX / Louisiana-Pacific Corporation
IP / International Paper Company
ALC / Alcon Inc.
QRVO / Qorvo, Inc.
T / AT&T Inc.
ADCT / ADC Therapeutics SA
FR / First Industrial Realty Trust, Inc.
BAX / Baxter International Inc.
SWAV / Shockwave Medical, Inc.
SRPT / Sarepta Therapeutics, Inc.
DUK / Duke Energy Corporation
TM / Toyota Motor Corporation - Depositary Receipt (Common Stock)
WY / Weyerhaeuser Company
EMLP / First Trust Exchange-Traded Fund IV - First Trust North American Energy Infrastructure Fund
ABMD / Abiomed Inc.
LMBS / First Trust Exchange-Traded Fund IV - First Trust Low Duration Opportunities ETF
/ Nuveen Pennsylvania Municipal Value Fund
BDX / Becton, Dickinson and Company
TEL / TE Connectivity plc
MUB / iShares Trust - iShares National Muni Bond ETF
FNX / First Trust Exchange-Traded AlphaDEX Fund - First Trust Mid Cap Core AlphaDEX Fund
XLE / The Select Sector SPDR Trust - The Energy Select Sector SPDR Fund
ACN / Accenture plc
MRK / Merck & Co., Inc.
IGIB / iShares Trust - iShares 5-10 Year Investment Grade Corporate Bond ETF
LUMN / Lumen Technologies, Inc.
MAR / Marriott International, Inc.
CRIS / Curis, Inc.
IWM / iShares Trust - iShares Russell 2000 ETF
MDT / Medtronic plc
C.WSA / Citigroup, Inc.
BOTZ / Global X Funds - Global X Robotics & Artificial Intelligence ETF
CREE / Cree, Inc.
FDN / First Trust Exchange-Traded Fund - First Trust Dow Jones Internet Index Fund
WRAP / Wrap Technologies, Inc.
RADA / Rada Electronic Industries
VanEck Vectors High-Yield Muni. Index ETF / ETF (92189F361)
MGA / Magna International Inc.
MET / MetLife, Inc.
SIRIUS XM Radio Inc. / (82966U103)
SVVC / Firsthand Technology Value Fund, Inc.
/ Weight Watchers International, Inc.
SMMU / PIMCO ETF Trust - PIMCO Short Term Municipal Bond Active Exchange-Traded Fund
NLOK / NortonLifeLock Inc
ROM / ProShares Trust - ProShares Ultra Technology
IFN / The India Fund, Inc.
RCS / PIMCO Strategic Income Fund, Inc.
MGRC / McGrath RentCorp
RGR / Sturm, Ruger & Company, Inc.
FIXD / First Trust Exchange-Traded Fund VIII - First Trust TCW Opportunistic Fixed Income ETF
PSK / SPDR Series Trust - SPDR ICE Preferred Securities ETF
GDP / Goodrich Petroleum Corp.
US2655041000 / Dunkin' Brands Group, Inc.
SHM / SPDR Series Trust - SPDR Nuveen ICE Short Term Municipal Bond ETF
VGR / Vector Group Ltd.
FNDX / Schwab Strategic Trust - Schwab Fundamental U.S. Large Company ETF
SCWX / SecureWorks Corp.
US5391831030 / Livongo Health, Inc.
CNC / Centene Corporation
DOCU / DocuSign, Inc.
INOD / Innodata Inc.
BAC.WS / Bank of America Corp. (Warrants)
Invesco QQQ ETF / ETF (631100104)
VPG / Vishay Precision Group, Inc.
SPMD / SPDR Series Trust - SPDR Portfolio S&P 400 Mid Cap ETF
BSV / Vanguard Bond Index Funds - Vanguard Short-Term Bond ETF
PFE / Pfizer Inc.
ETN / Eaton Corporation plc
PWR / Quanta Services, Inc.
SPY / SPDR S&P 500 ETF
AMZN / Amazon.com, Inc. Call
RTX / RTX Corporation
ABT / Abbott Laboratories
BND / Vanguard Bond Index Funds - Vanguard Total Bond Market ETF
TTD / The Trade Desk, Inc.
TJX / The TJX Companies, Inc.
KMB / Kimberly-Clark Corporation
MDLZ / Mondelez International, Inc.
HON / Honeywell International Inc.
SCHF / Schwab Strategic Trust - Schwab International Equity ETF
NFLX / Netflix, Inc.
IBM / International Business Machines Corporation
CVX / Chevron Corporation
DSI / iShares Trust - iShares ESG MSCI KLD 400 ETF
V / Visa Inc.
JPST / J.P. Morgan Exchange-Traded Fund Trust - JPMorgan Ultra-Short Income ETF
WM / Waste Management, Inc.
CATH / Global X Funds - Global X S&P 500 Catholic Values ETF
SHOP / Shopify Inc.
PEP / PepsiCo, Inc.
PPL / PPL Corporation
PM / Philip Morris International Inc.
DLR / Digital Realty Trust, Inc.
JPM / JPMorgan Chase & Co.
META / Meta Platforms, Inc.
SPYG / SPDR Series Trust - SPDR Portfolio S&P 500 Growth ETF
GLW / Corning Incorporated
CSCO / Cisco Systems, Inc.
CAT / Caterpillar Inc.
MMM / 3M Company
ADP / Automatic Data Processing, Inc.
ORCL / Oracle Corporation
SCHX / Schwab Strategic Trust - Schwab U.S. Large-Cap ETF
EMR / Emerson Electric Co.
EEM / iShares, Inc. - iShares MSCI Emerging Markets ETF
LMT / Lockheed Martin Corporation
REGN / Regeneron Pharmaceuticals, Inc.
UTG / Reaves Utility Income Fund
VWO / Vanguard International Equity Index Funds - Vanguard FTSE Emerging Markets ETF
IJH / iShares Trust - iShares Core S&P Mid-Cap ETF
INTC / Intel Corporation
GOOG / Alphabet Inc. Call
PSX / Phillips 66
CI / The Cigna Group
UL / Unilever PLC - Depositary Receipt (Common Stock)
PG / The Procter & Gamble Company
MCD / McDonald's Corporation
GIS / General Mills, Inc.
JNJ / Johnson & Johnson
GMED / Globus Medical, Inc.
PSA / Public Storage
XAR / SPDR Series Trust - SPDR S&P Aerospace & Defense ETF
GDX / VanEck ETF Trust - VanEck Gold Miners ETF
MSFT / Microsoft Corporation
CWB / SPDR Series Trust - SPDR Bloomberg Convertible Securities ETF
VTV / Vanguard Index Funds - Vanguard Value ETF
FEX / First Trust Exchange-Traded AlphaDEX Fund - First Trust Large Cap Core AlphaDEX Fund
V / Visa Inc.
BSTZ / BlackRock Science and Technology Term Trust
US0153511094 / Alexion Pharmaceuticals, Inc.
COG / Cabot Oil & Gas Corp.
IWR / iShares Trust - iShares Russell Mid-Cap ETF
ROBO / Exchange Traded Concepts Trust - ROBO Global Robotics and Automation Index ETF
US21871D1037 / Corelogic Inc
TDC / Teradata Corporation
AMAT / Applied Materials, Inc.
DBX / Dropbox, Inc.
03765K104 / Aphria Inc.
US31816QAB77 / FireEye, Inc. Bond
US92220P1057 / Varian Medical Systems, Inc.
983793AA8 / XPO Logistics, Inc. Bond
ROKU / Roku, Inc.
US83088V1026 / Slack Technologies Inc
WSFS / WSFS Financial Corporation
QCOM / QUALCOMM Incorporated
ROST / Ross Stores, Inc.
AGX / Argan, Inc.
TSC / Tristate Capital Holdings Inc
JEF / Jefferies Financial Group Inc.
VYM / Vanguard Whitehall Funds - Vanguard High Dividend Yield ETF
NBB / Nuveen Taxable Municipal Income Fund
AOA / iShares Trust - iShares Core 80/20 Aggressive Allocation ETF
EEMV / iShares, Inc. - iShares MSCI Emerging Markets Min Vol Factor ETF
HRL / Hormel Foods Corporation
TSCO / Tractor Supply Company
NVTA / Invitae Corporation
DXCM / DexCom, Inc.
PFF / iShares Trust - iShares Preferred and Income Securities ETF
MRNA / Moderna, Inc.
O / Realty Income Corporation
LEU / Centrus Energy Corp.
ZBH / Zimmer Biomet Holdings, Inc.
BIP / Brookfield Infrastructure Partners L.P. - Limited Partnership
CUK / Carnival Corporation & plc - Depositary Receipt (Common Stock)
USAC / USA Compression Partners, LP - Limited Partnership
LBRDA / Liberty Broadband Corporation
KHC / The Kraft Heinz Company
VNQ / Vanguard Specialized Funds - Vanguard Real Estate ETF
FAST / Fastenal Company
ALK / Alaska Air Group, Inc.
BAH / Booz Allen Hamilton Holding Corporation
THO / THOR Industries, Inc.
ACLS / Axcelis Technologies, Inc.
BRK.B / Berkshire Hathaway Inc.
VPU / Vanguard World Fund - Vanguard Utilities ETF
KO / The Coca-Cola Company
EFA / iShares Trust - iShares MSCI EAFE ETF
WMT / Walmart Inc.
GOOG / Alphabet Inc.
DE / Deere & Company
AMD / Advanced Micro Devices, Inc.
BX / Blackstone Inc.
GS / The Goldman Sachs Group, Inc.
CVS / CVS Health Corporation
MPC / Marathon Petroleum Corporation
XLC / The Select Sector SPDR Trust - The Communication Services Select Sector SPDR Fund
ARNC / Arconic Corporation
RLI / RLI Corp.
NKE / NIKE, Inc.
HPQ / HP Inc.
CERS / Cerus Corporation
SLB / Schlumberger Limited
LIN / Linde plc
WU / The Western Union Company
GENN / Genesis Healthcare, Inc.
PFPT / Proofpoint Inc
PENN / PENN Entertainment, Inc.
WBA / Walgreens Boots Alliance, Inc.
OUNZ / VanEck Merk Gold ETF
UGI / UGI Corporation
ZM / Zoom Communications Inc.
ROK / Rockwell Automation, Inc.
BCPC / Balchem Corporation
DOW / Dow Inc.
DOW / Dow Inc.
CARR / Carrier Global Corporation
CHRW / C.H. Robinson Worldwide, Inc.
APPS / Digital Turbine, Inc.
110122157 / Bristol Meyers Squibb CVR Exp. 12/31/2020
FIVN / Five9, Inc.
TEVA / Teva Pharmaceutical Industries Limited - Depositary Receipt (Common Stock)
MTCH / Match Group, Inc.
GOLF / Acushnet Holdings Corp.
NVS / Novartis AG - Depositary Receipt (Common Stock)
ARCC / Ares Capital Corporation
NID / Nuveen Intermediate Duration Municipal Term Fund
XYL / Xylem Inc.
WFC / Wells Fargo & Company
ORMP / Oramed Pharmaceuticals Inc.
SCU / Sculptor Capital Management Inc - Class A
NFG / National Fuel Gas Company
ETSY / Etsy, Inc.
ARGO / Argo Group International Holdings, Inc.
ALDX / Aldeyra Therapeutics, Inc.
PETS / PetMed Express, Inc.
TD / The Toronto-Dominion Bank
TDOC / Teladoc Health, Inc.
VGT / Vanguard World Fund - Vanguard Information Technology ETF
VICSX / Vanguard Scottsdale Funds - Vanguard IT Corporate Bond Index Fund Admiral
PTON / Peloton Interactive, Inc.
VEEV / Veeva Systems Inc.
GPC / Genuine Parts Company
IGSB / iShares Trust - iShares 1-5 Year Investment Grade Corporate Bond ETF
IBB / iShares Trust - iShares Biotechnology ETF
SMOG / VanEck ETF Trust - VanEck Low Carbon Energy ETF
UAA / Under Armour, Inc.
KR / The Kroger Co.
GSK / GSK plc - Depositary Receipt (Common Stock)
FSK / FS KKR Capital Corp.
CRM / Salesforce, Inc.
AAL / American Airlines Group Inc.
AAL / American Airlines Group Inc. Call
NYMX / Nymox Pharmaceutical Corp
NKTR / Nektar Therapeutics
PDM / Piedmont Realty Trust, Inc.
EMN / Eastman Chemical Company
AVGO / Broadcom Inc.
SO / The Southern Company
CGEN / Compugen Ltd.
HSY / The Hershey Company
SWBI / Smith & Wesson Brands, Inc.
LYFT / Lyft, Inc.
PPG / PPG Industries, Inc.
VSH / Vishay Intertechnology, Inc.
EA / Electronic Arts Inc.
PEG / Public Service Enterprise Group Incorporated
VIRT / Virtu Financial, Inc.
ESGD / iShares Trust - iShares ESG Aware MSCI EAFE ETF
XLF / The Select Sector SPDR Trust - The Financial Select Sector SPDR Fund
IYY / iShares Trust - iShares Dow Jones U.S. ETF
ORLY / O'Reilly Automotive, Inc.
MODG / Topgolf Callaway Brands Corp.
CME / CME Group Inc.
EPAM / EPAM Systems, Inc.
BBY / Best Buy Co., Inc.
GDEN / Golden Entertainment, Inc.
HTGC / Hercules Capital, Inc.
GSBD / Goldman Sachs BDC, Inc.
ACST / Grace Therapeutics, Inc.
EXC / Exelon Corporation
BYND / Beyond Meat, Inc.
SNA / Snap-on Incorporated
AVEO / AVEO Pharmaceuticals Inc
WEC / WEC Energy Group, Inc.
SPB / Spectrum Brands Holdings, Inc.
HRB / H&R Block, Inc.
BMY / Bristol-Myers Squibb Company
ITW / Illinois Tool Works Inc.
YUM / Yum! Brands, Inc.
AFL / Aflac Incorporated
GLD / SPDR Gold Trust
GOLD / Barrick Mining Corporation
CTSH / Cognizant Technology Solutions Corporation
NUV / Nuveen Municipal Value Fund, Inc.
HYG / iShares Trust - iShares iBoxx $ High Yield Corporate Bond ETF
IEFA / iShares Trust - iShares Core MSCI EAFE ETF
MBB / iShares Trust - iShares MBS ETF
ACWX / iShares Trust - iShares MSCI ACWI ex U.S. ETF
FNCB / FNCB Bancorp, Inc.
SNOW / Snowflake Inc.
MRBK / Meridian Corporation
SCHB / Schwab Strategic Trust - Schwab U.S. Broad Market ETF
WELL / Welltower Inc.
ABUS / Arbutus Biopharma Corporation
FSLY / Fastly, Inc.
WKHS / Workhorse Group Inc.
VTI / Vanguard Index Funds - Vanguard Total Stock Market ETF
SBUX / Starbucks Corporation
LDOS / Leidos Holdings, Inc.
CTVA / Corteva, Inc.
ABBV / AbbVie Inc.
FTNT / Fortinet, Inc.
ULTA / Ulta Beauty, Inc.
FLXN / Horizon Funds - Horizon Flexible Income ETF
BVXV / Biondvax Pharmaceuticals Ltd - ADR
SPOT / Spotify Technology S.A.
NEE / NextEra Energy, Inc.
ITEQ / Amplify ETF Trust - Amplify BlueStar Israel Technology ETF
DBEF / DBX ETF Trust - Xtrackers MSCI EAFE Hedged Equity ETF
WPS / iShares Trust - iShares International Developed Property ETF
SMG / The Scotts Miracle-Gro Company
IWS / iShares Trust - iShares Russell Mid-Cap Value ETF
PPHI / Positive Physicians Holdings, Inc.
EFAV / iShares Trust - iShares MSCI EAFE Min Vol Factor ETF
SUB / iShares Trust - iShares Short-Term National Muni Bond ETF
VCSH / Vanguard Scottsdale Funds - Vanguard Short-Term Corporate Bond ETF
SHY / iShares Trust - iShares 1-3 Year Treasury Bond ETF
FFTY / Innovator ETFs Trust - Innovator IBD 50 ETF
NOBL / ProShares Trust - ProShares S&P 500 Dividend Aristocrats ETF
SCHE / Schwab Strategic Trust - Schwab Emerging Markets Equity ETF
IGF / iShares Trust - iShares Global Infrastructure ETF
RWO / SPDR Index Shares Funds - SPDR Dow Jones Global Real Estate ETF
ET / Energy Transfer LP - Limited Partnership
IJJ / iShares Trust - iShares S&P Mid-Cap 400 Value ETF
LVHD / Legg Mason ETF Investment Trust - Franklin U.S. Low Volatility High Dividend Index ETF
PAWZ / ProShares Trust - ProShares Pet Care ETF
GAMR / Amplify ETF Trust - Amplify Video Game Leaders ETF
MA / Mastercard Incorporated
PINS / Pinterest, Inc.
FIBK / First Interstate BancSystem, Inc.
LQD / iShares Trust - iShares iBoxx $ Investment Grade Corporate Bond ETF
VXF / Vanguard Index Funds - Vanguard Extended Market ETF
EPD / Enterprise Products Partners L.P. - Limited Partnership
NAD / Nuveen Quality Municipal Income Fund
HIMX / Himax Technologies, Inc. - Depositary Receipt (Common Stock)
XLRE / The Select Sector SPDR Trust - The Real Estate Select Sector SPDR Fund
XLV / The Select Sector SPDR Trust - The Health Care Select Sector SPDR Fund
VNM / VanEck ETF Trust - VanEck Vietnam ETF
KSS / Kohl's Corporation
IJK / iShares Trust - iShares S&P Mid-Cap 400 Growth ETF
IEMG / iShares, Inc. - iShares Core MSCI Emerging Markets ETF
PFFD / Global X Funds - Global X U.S. Preferred ETF
QDF / FlexShares Trust - FlexShares Quality Dividend Index Fund
LH / Labcorp Holdings Inc.
IJS / iShares Trust - iShares S&P Small-Cap 600 Value ETF
VEU / Vanguard International Equity Index Funds - Vanguard FTSE All-World ex-US ETF
IJT / iShares Trust - iShares S&P Small-Cap 600 Growth ETF
VIS / Vanguard World Fund - Vanguard Industrials ETF
SCHM / Schwab Strategic Trust - Schwab U.S. Mid-Cap ETF
TIP / iShares Trust - iShares TIPS Bond ETF
IWP / iShares Trust - iShares Russell Mid-Cap Growth ETF
ITOT / iShares Trust - iShares Core S&P Total U.S. Stock Market ETF
BIGC / Commerce.com, Inc.
BLNK / Blink Charging Co.
RDS.A / Shell Plc - ADR (Representing Ordinary Shares - Class A)
GBTC / Grayscale Bitcoin Trust (BTC)
NZF / Nuveen Municipal Credit Income Fund
OTIS / Otis Worldwide Corporation
UBER / Uber Technologies, Inc.
BIDU / Baidu, Inc. - Depositary Receipt (Common Stock)
SPLK / Splunk Inc.
TRIP / Tripadvisor, Inc.
NBRV / Nabriva Therapeutics Plc
LUV / Southwest Airlines Co.
DAL / Delta Air Lines, Inc.
AKAM / Akamai Technologies, Inc.
GILD / Gilead Sciences, Inc.
PNC / The PNC Financial Services Group, Inc.
SNY / Sanofi - Depositary Receipt (Common Stock)
ISRA / VanEck ETF Trust - VanEck Israel ETF
DZSI / DZS Inc.
STX / Seagate Technology Holdings plc
MU / Micron Technology, Inc.
PKE / Park Aerospace Corp.
COST / Costco Wholesale Corporation
ICLN / iShares Trust - iShares Global Clean Energy ETF
CPT / Camden Property Trust
FSR / Fisker Inc.
NOC / Northrop Grumman Corporation
CGC / Canopy Growth Corporation
MMP / Magellan Midstream Partners L.P.
BABA / Alibaba Group Holding Limited - Depositary Receipt (Common Stock)
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock)
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Call
TGT / Target Corporation
PYPL / PayPal Holdings, Inc.
ACB / Aurora Cannabis Inc.
PD / PagerDuty, Inc.
FSLR / First Solar, Inc.
ILMN / Illumina, Inc.
MDXG / MiMedx Group, Inc.
WTRG / Essential Utilities, Inc.
AMLP / ALPS ETF Trust - Alerian MLP ETF
SYK / Stryker Corporation
CRWD / CrowdStrike Holdings, Inc.
LOW / Lowe's Companies, Inc.
MO / Altria Group, Inc.
CL / Colgate-Palmolive Company
NET / Cloudflare, Inc.
GE / General Electric Company
DEO / Diageo plc - Depositary Receipt (Common Stock)
AMZN / Amazon.com, Inc.
AMGN / Amgen Inc.
UNH / UnitedHealth Group Incorporated
GOOGL / Alphabet Inc.
PALI / Palisade Bio, Inc.
DIS / The Walt Disney Company
NVDA / NVIDIA Corporation
SQ / Block, Inc.
BA / The Boeing Company
HD / The Home Depot, Inc.
TFC / Truist Financial Corporation
TNXP / Tonix Pharmaceuticals Holding Corp.
CMCSA / Comcast Corporation
CMI / Cummins Inc.
XOM / Exxon Mobil Corporation
LLY / Eli Lilly and Company
RIO / Rio Tinto Group - Depositary Receipt (Common Stock)
VUG / Vanguard Index Funds - Vanguard Growth ETF
KMI / Kinder Morgan, Inc.
UPS / United Parcel Service, Inc.
AMT / American Tower Corporation
KKR / KKR & Co. Inc.
ALGN / Align Technology, Inc.
COP / ConocoPhillips
PAYX / Paychex, Inc.
ANVS / Annovis Bio, Inc.